RESUMEN
In this work, the influence of two different types of cations on the gel formation and structure of mixed gel networks comprised of semiconductor (namely CdSe/CdS nanorods NR) and Au nanoparticles (NP) as well as on the respective monocomponent gels is investigated. Heteroassemblies built from colloidal building blocks are usually prepared by ligand removal or cross-linking, thus, both the surface chemistry and the destabilising agent play an essential role in the gelation process. Due to the diversity of the composition, morphology, and optical properties of the nanoparticles, a versatile route to fabricate functional heteroassemblies is of great demand. In the present work, the optics, morphology, and gelation mechanism of pure semiconductor and noble metal as well as their mixed nanoparticle gel networks are revealed. The influence of the gelation agents (bivalent and trivalent cations) on the structure-property correlation is elucidated by photoluminescence, X-ray photoelectron spectroscopy, and electron microscopy measurements. The selection of cations drastically influences the nano- and microstructure of the prepared gel network structures driven by the affinity of the cations to the ligands and the nanoparticle surface. This gelation technique provides a new platform to control the formation of porous assemblies based on semiconductor and metal nanoparticles.
RESUMEN
The assembly of CdSe/CdS dot/rod nanocrystals (NCs) with variable length of ZnS tips into aerogel networks is presented. To this end, a partial region selective cation exchange procedure is performed replacing Cd by Zn starting at the NC tip. The produced aerogel networks are investigated structurally and optically. The networks of tip-to-tip connected NCs have an intricate band structure with holes confined to the CdSe cores while electrons are delocalized within the CdS also within connected building blocks. However, the ZnS tips act as a barrier of variable length and strength between the NC building blocks partly confining the electrons. This results in NC based aerogel networks with tunable strength of coupling between building blocks.
RESUMEN
A novel potentiometric solid contact (SC) sensor was developed to determine the anticancer drug gefitinib by employing a polyaniline nanofibers/carboxylated multi-walled carbon nanotube (PANI-NFs/c-MWCNT) nano-composite as an ion to electron transducer. The FDA approved gefitinib as the first line treatment of non-small cell lung cancer (NSCLC) that represents 90% of lung carcinomas. The PANI-NFs/C-MWCNT nano-composite was synthesized and characterized using Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM). Twenty-three polyvinyl chloride (PVC) based sensors were fabricated through a systematic approach using different plasticizers and cationic exchangers to investigate their effects on the performance of the developed sensors. The incorporation of calix[8]arene (CX-8) notably enhanced the sensitivity of the developed sensor, confirmed by the docking study. The optimized sensor attained a fast and stable Nernstian slope of 29.14 mV per decade over the concentration range from 1.0 × 10-2 to 1.5 × 10-6 M with a LOD of 1.0 × 10-6 M. The proposed method represents the first potentiometric sensor for GEF assay according to the authors' knowledge. It was validated as per the IUPAC guidelines and efficiently applied to determine GEF in its tablets and human plasma. This encourages quality control, bioavailability, and clinical centers to utilize the portable GEF sensor in its routine analysis.