[EFFECT OF LOW-INTENSITY RED LASER ON GROWTH OF STAPHYLOCOCCUS AUREUSAND SENSITIZING EFFECT OF PHOTODITAZIN].

AIM: Study the effect of laser emission in the red spectrum on growth of methicillin- sensitive. and methicillin-resistant strains of Staphylococcus aureus, as well as photodynamic effect of photosensitizer photoditazin. MATERIALS AND METHODS: Effect of light of semiconduc- tor red laser (X 660 nm, 100 mW/cm2) at 30,'60, 90 and 180 J/cm2 on growth of S. aureus colonies was determined. Time of exposure 5; 10, 15 and 30 minutes. In certain series of experiments bacterial cells were sensitized in advance by a Water. solution of photoditazin at a concentration of5xl0-6 M. RESULTS: Red laser emission was established to cause a pronounced suppression of bacterial growth. This effect on standard S. aureus strain only took place dur- ing use of relatively high exposure doses (180 J/cm2). Photosensitivity of methicillin-resistant strain turned out to be significantly higher: bacteriostatic effect of red light was noted already at the dose of 60 J/cm2. Treatment of bacterial cells with photoditazin in advance signifi- cantly enhanced growth-inhibiting effect of laser light.

STRUCTURAL CHARACTERISTICS OF HUMAN AND OTHER MAMMALIAN ENDOTHELIAL CELLS.

Endothelial cells perform a number of important functions in the organism, and their dysfunction plays an important role in pathogenesis of a wide range of diseases. This review deals with the current literature data on structural characteristics of endothelial cells. A special section is devoted to endothelial cells development and differentiation. Structural aspects of endothelial cells cytoplasm and transport structures organization are discussed. Particular attention is paid to the structural heterogeneity of endothelial cells. Data on planar and apical- basal polarity of endothelial cells are reviewed separately.

[Effect of Azospirillum brasilense lectin on the kinetics of lymph nodes cell populations and cytokine status in experimental animals]. / Vliianie lektina Azospirillum brasilense na kinetiku kletochnykh populiatsii mezenterial'nykh limfaticheskikh uzlov i dinamiku tsitokinovogo statusa éksperimental'nykh zhivotnykh.

The complex study of the influence of A. brasilense Sp 7 lectin with carbohydrate specificity to L-fucose and D-galactose on the dynamics of cell populations in different structural functional zones of the white mice mesentery, as well as on the capacity of immunocompetent cells of mesenterial lymph nodes for synthesizing cytokines (interleukin-1, interleukin-6 and tumor necrosis factor), was carried out. A single oral administration of bacterial lectin in a dose of 4.5 micrograms produced a pronounced immunostimulating effect.