RESUMEN
Glioblastoma multiforme (GBM) is an aggressive glioma that is infrequently diagnosed in the paediatric population. GBM and other primary brain tumours have rarely been associated with paraneoplastic syndromes. We report an unusual case of an 8-year-old boy presenting with an inability to abduct his left eye and almost complete ophthalmoplegia of his right eye, prior to any radiological evidence of GBM. This is the first documented case of paediatric GBM presenting with bilateral asymmetric ophthalmoplegia.
RESUMEN
A 32-year-old male presented to the emergency department for confusion, dyspnea, and a "white out" of his central vision over the preceding 24 hours. The patient had recently consumed a bottle of alcohol purchased overseas. Bloodwork revealed a severe metabolic acidosis (pH 6.90) and a critically high methanol level of 28.9 mmol/l. Shortly after presentation, the patient went into respiratory failure and became comatose. He was intubated and admitted to the ICU.
RESUMEN
OBJECTIVE: Research experience is one criterion of the selection process for applicants to residency training programs. We aim to quantify temporal trends in research productivity of medical students who matched into a canadian ophthalmology residency program. DESIGN: Retrospective database review. PARTICIPANTS: A total of 465 residents commencing ophthalmology training from 2010 to 2022 in 15 Canadian ophthalmology residency programs. METHODS: The names of all residents commencing training in ophthalmology in all Canadian programs from 2010 to 2022 were identified. Bibliometric data including publication count and type, authorship position, and H-index corresponding to the match year were extracted from the Scopus database. Descriptive and univariate statistics were used to characterize and assess trends in research productivity. RESULTS: A total of 461 ophthalmology residents (99% complete data set) from all 15 residency programs representing 1179 publications, including 679 ophthalmology-related publications, were identified. Most publications were original research (676; 58%), followed by case reports and letters (324; 27%) and reviews (162; 14%). Overall, 62% of residents had at least 1 publication at the time of the match, with a mean of 2.56 ± 3.49 publications and a mean H-index of 1.03 ± 1.48 publications. There was a significant increase (p < 0.001) in all research productivity metrics except senior authorship in the period 2019-2022 compared with 2010-2018. Notably, 91% of residents had ≥1 publication in 2022 compared with 38% in 2010. CONCLUSION: First-year ophthalmology resident publication productivity doubled from 2010-2016 to 2017-2022 suggesting a greater emphasis on scholarly work from medical trainees, a trend similar to that reported in other specialties.