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1.
Singapore Med J ; 46(2): 90-2, 2005 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-15678292

RESUMEN

Focal nodular hyperplasia (FNH) is a benign liver tumour with an asymptomatic course, rarely causing complications. When the diagnosis is certain, only watchful observation is necessary. We highlight an interesting case of a 42-year-old woman with a FNH that ruptured and became haemorrhagic, thus presenting as an acute surgical abdomen. The diagnosis was only established after surgical resection with histopathological confirmation. Although haemorrhage of hepatic FNH is extremely rare, this case highlights the small risk of rupture in large lesions.


Asunto(s)
Abdomen Agudo/etiología , Hiperplasia Nodular Focal/complicaciones , Abdomen Agudo/diagnóstico por imagen , Adulto , Femenino , Hiperplasia Nodular Focal/diagnóstico por imagen , Humanos , Rotura Espontánea/diagnóstico por imagen , Tomografía Computarizada por Rayos X
2.
Singapore Med J ; 45(1): 6-8, 2004 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-14976575

RESUMEN

Recurrent appendicitis is defined when patients with recurring similar right iliac fossa pain had acute appendicitis confirmed at the time of operation and the pain completely subsided after surgery. We conducted a retrospective study on our patients with appendicitis. There were 290 patients with appendicitis over a two-year period and 33 patients (11%) had reported recurring pain prior to the presentation. Majority had one prior episode but 15% had multiple episodes of right iliac fossa pain. Fifty-eight percent of the episode occur within six months of the presentation. We conclude that recurrent appendicitis should be considered as a differential diagnosis in patients with recurrent right iliac fossa pain.


Asunto(s)
Dolor Abdominal/epidemiología , Apendicitis/diagnóstico , Apendicitis/epidemiología , Dolor Abdominal/fisiopatología , Adulto , Comorbilidad , Femenino , Humanos , Íleon/fisiopatología , Incidencia , Masculino , Recurrencia , Estudios Retrospectivos , Distribución por Sexo , Singapur/epidemiología
3.
IEEE Trans Biomed Eng ; 59(6): 1593-7, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22410954

RESUMEN

Radio-frequency ablation (RFA) has been used in liver surgery to minimize blood loss during tissue division. However, the current RFA tissue division method lacks an effective way of determining the stoppage of blood flow. There is limitation on the current state-of-the-art laser Doppler flow sensor due to its small sensing area. A new technique was proposed to use bioimpedance for blood flow sensing. This paper discusses a new geometrical multiscale model of the liver bioimpedance incorporating blood flow impedance. This model establishes correlation between the physical tissue structure and bioimpedance measurement. The basic Debye structure within a multilevel framework is used in the model to account for bioimpedance dispersion. This dispersion is often explained by the Cole-Cole model that includes a constant phase element without physical explanation. Our model is able to account for reduced blood flow in its output with changes in permittivity in gamma dispersion that is mainly due to the polarization of water molecules. This study demonstrates the potential of a multiscale model in determining the stoppage of blood flow during surgery.


Asunto(s)
Hígado/fisiología , Modelos Biológicos , Pletismografía de Impedancia/métodos , Animales , Simulación por Computador , Humanos
4.
Singapore Med J ; 50(3): e100-1, 2009 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-19352550

RESUMEN

Carcinoid tumours of the gastrointestinal tract are uncommon, generally slow-growing and associated with a good prognosis. We present a 52-year-old Chinese woman with a carcinoid at the ampulla of Vater, a site far less common than other areas of the gastrointestinal tract. Preoperative imaging showed a pancreatic mass with displacement and possible invasion of the portal vein associated with peripancreatic nodal enlargement. A radical pancreaticoduodenectomy with portal vein wedge excision was performed. An intraoperative biopsy of the enlarged nodes was negative for malignancy and postoperative histology of the large pancreatic mass yielded a surprising finding of a carcinoid tumour at the ampulla of Vater with a large inflammatory pancreatic mass adherent to the portal vein. This is an uncommon case associated with "pseudotumour pancreatitis", causing biliary and pancreatic duct obstruction mimicking a large tumour in the head of the pancreas.


Asunto(s)
Ampolla Hepatopancreática/patología , Tumor Carcinoide/complicaciones , Neoplasias de la Vesícula Biliar/complicaciones , Granuloma de Células Plasmáticas/etiología , Tumor Carcinoide/fisiopatología , Tumor Carcinoide/cirugía , Femenino , Neoplasias de la Vesícula Biliar/fisiopatología , Neoplasias de la Vesícula Biliar/cirugía , Granuloma de Células Plasmáticas/patología , Granuloma de Células Plasmáticas/cirugía , Humanos , Persona de Mediana Edad , Pancreaticoduodenectomía , Pronóstico
5.
Singapore Med J ; 50(3): e102-4, 2009 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-19352551

RESUMEN

We present a 33-year-old Chinese woman with Wilson's disease in whom ultrasonography and computed tomography showed gallbladder features suggestive of acute cholecystitis. Incongruence in liver function prompted further investigations with the final diagnosis of Wilson's disease, complicated by oedema of the gallbladder mimicking acute cholecystitis. The patient was subsequently treated nonoperatively, and is well on follow-up.


Asunto(s)
Colecistitis Aguda/etiología , Degeneración Hepatolenticular/diagnóstico , Adulto , Colecistitis Aguda/diagnóstico , Colecistitis Aguda/diagnóstico por imagen , Colecistitis Aguda/tratamiento farmacológico , Diagnóstico Diferencial , Femenino , Vesícula Biliar/patología , Enfermedades de la Vesícula Biliar , Degeneración Hepatolenticular/complicaciones , Degeneración Hepatolenticular/diagnóstico por imagen , Degeneración Hepatolenticular/tratamiento farmacológico , Humanos , Penicilinas/uso terapéutico , Tomografía Computarizada por Rayos X , Ultrasonografía , Compuestos de Zinc/uso terapéutico
6.
Singapore Med J ; 48(8): e224-6, 2007 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-17657371

RESUMEN

We describe a 43-year-old man who had a difficult endoscopic retrograde cholangiopancreatography, allowing only placement of a stent without removal of the common bile duct stone. He subsequently underwent laparoscopic cholecystectomy with laparoscopic common bile duct exploration and primary closure after laparoscopic choledochotomy.


Asunto(s)
Colecistectomía Laparoscópica/métodos , Conducto Colédoco/cirugía , Cálculos Biliares/cirugía , Stents , Adulto , Humanos , Masculino
7.
Arch Dis Child ; 86(6): 407-10, 2002 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-12023168

RESUMEN

AIMS: To evaluate effects of a low energy diet, with or without strength training, on blood lipid profile in obese children. METHODS: Eighty two obese children were enrolled into a six week dietary programme, and were randomly allocated to a training group or a non-training group. The training group underwent regular exercise sessions with emphasis on strength training. RESULTS: Height increased significantly, with a non-significant reduction in body mass index. Fat free mass increased significantly in the training group. Serum total cholesterol was significantly reduced in both groups. The LDL:HDL ratio significantly decreased in the training group. CONCLUSION: Results support the potentially beneficial effects of both diet and physical training. Further and longer term evaluation of such programmes is required.


Asunto(s)
Terapia por Ejercicio/métodos , Lípidos/sangre , Obesidad/terapia , Adulto , Índice de Masa Corporal , Niño , Terapia Combinada/métodos , Ingestión de Energía , Femenino , Humanos , Masculino , Obesidad/sangre , Obesidad/dietoterapia , Aptitud Física
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