RESUMEN
During one year from July 1992 to July 1993, we performed usual hemostasis tests in a population or 3,700 patients. We found 12 patients with a lupus like anticoagulant (incidence: 1/1,000). Among these 12, four had unexplained polyneuropathy or myélopathy. Lupus like anticoagulant was either isolated (two cases), either associated with thrombosis (two cases). We report these four cases and we discuss the causal or uncasual nature of this association.
Asunto(s)
Enfermedades de la Médula Ósea/sangre , Inhibidor de Coagulación del Lupus/análisis , Enfermedades del Sistema Nervioso/sangre , Anciano , Síndrome Antifosfolípido/diagnóstico , Diagnóstico Diferencial , Humanos , Masculino , Estudios Prospectivos , Tromboflebitis/sangreRESUMEN
Streptococcus anginosus, the term suggested to cover a set of streptococci previously known under various names (milleri, MG, anginosus, intermedius, constellatus), is characterized by a propensity to create parenchymatous abscesses, essentially cerebral or hepatic, particularly within the terms of septicemia. These abscesses are sometimes difficult to detect due to a difficult or non-existent symptomatology. The authors report on four cases illustrating the necessity to search for them systematically by cerebral CT scan and abdominal echography or CT scan in all cases of septicemia caused by Streptococcus anginosus.
Asunto(s)
Bacteriemia/complicaciones , Absceso Encefálico/microbiología , Absceso Hepático/microbiología , Infecciones Estreptocócicas/complicaciones , Anciano , Absceso Encefálico/diagnóstico por imagen , Humanos , Absceso Hepático/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Tomografía Computarizada por Rayos X , UltrasonografíaRESUMEN
Emphysematous cystitis is a rare urinary infection which is characterized by gas collection within the bladder wall, with or without gas in the lumen itself. The diagnostic is radiologic. We report a new case, discovered with C.T. and we discuss the interest of this technique.
Asunto(s)
Cistitis , Enfisema , Anciano , Anciano de 80 o más Años , Cistitis/diagnóstico por imagen , Enfisema/diagnóstico por imagen , Femenino , Humanos , Tomografía Computarizada por Rayos XRESUMEN
OBJECTIVES: An abbreviated 2-1-1 schedule for post-exposure rabies vaccination would theoretically lead to more rapid production of specific antibodies than the classical schedule. We measured early serological response to the 2-1-1 schedule. METHODS: Patients consulting the antirabies centre of the Epinal hospital from June 1992 to June 1993 who had never been vaccinated and whose exposure history justified antirabies vaccination were included in this study. Fifty subjects were vaccinated with PVRV (purified vero rabies vaccine, Pasteur Institute) cultured on VERO (vervet monkey origin) cells using the abbreviated 2-1-1 schedule of 2 doses (0.5 ml = 2.5 IU/dose) on day 0 and 1 dose on days 7 and 21. Antirabies antibodies were assayed using the Platelia Rage immunoenzyme method (Diagnostic Pasteur) on day 21. Titres above 0.5 IU were considered to give protection and non-protected subjects were seen again on day 28 for a supplementary dose. RESULTS: Only 34 subjects (68%) had protective antibody titres on day 21, but by day 28, 48 (96%) had acquired immunity. In this study population, the age range was from 1 to 83 years and age over 30 years appeared to delay antibody formation. CONCLUSION: These findings emphasize the importance of initial antirabies immunoglobulins if short incubation in suspected and the need for serological follow-up if delayed antibody formation is suspected (subjects over 30).