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1.
AJNR Am J Neuroradiol ; 22(3): 564-70, 2001 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-11237985

RESUMEN

BACKGROUND AND PURPOSE: Macrocrania is a common pediatric clinical condition affecting up to 5% of the population. The purpose of this study was to determine clinical and imaging predictors that are useful in the differentiation of disorders requiring surgical treatment from those that can be treated medically in children with macrocrania. METHODS: In a 3-year 7-month retrospective study, 88 patients (median age, 8 months; interquartile range, 5--13 months) with macrocrania and no known underlying neurologic disorder underwent imaging of the brain (sonography, n = 36; CT, n = 31; MR imaging = 21). The study was conducted in a pediatric tertiary care referral center. Clinical and imaging data were correlated to final diagnosis by means of logistic regression and receiver operating characteristic curves. RESULTS: Sixteen (18%) of the patients had disorders requiring surgery: communicating hydrocephalus, n = 7; noncommunicating hydrocephalus, n = 3; hemorrhagic subdural collections, n = 3; neoplasm, n = 1; encysted cavum septi pellucidi, n = 1; and vein of Galen malformation, n = 1. Clinical predictors of disorders requiring surgery included vomiting (P =.007), labor instrumentation (P =.026), developmental delay (P =.008), and abnormal neurologic findings (P =.028). Imaging predictors of disorders requiring surgery included a focal space-occupying lesion (P <.0001) and moderate-to-severe ventriculomegaly (P <.0001). The diagnostic sensitivity of the combination of independent clinical and imaging predictors was higher than that of independent clinical predictors alone, being 100% (95% confidence interval = 96.9%, 100%) and 93.8% (95% confidence interval = 88.7%, 98.8%), respectively. A trend indicated that the area under the receiver operating characteristic curve for clinical plus imaging findings (0.95) was greater than that for clinical findings alone (0.85) (P =.09). An increase in the number of clinical and imaging predictors was highly correlated with an increased risk of a disorder requiring surgery (P <.0001). CONCLUSION: Baseline neuroimaging is indicated for children with macrocrania because the combination of clinical and imaging predictors has the best diagnostic performance in determining the need for surgical versus nonsurgical management.


Asunto(s)
Cráneo/patología , Encefalopatías/diagnóstico , Encefalopatías/patología , Encefalopatías/cirugía , Cefalometría , Hemorragia Cerebral/diagnóstico , Hemorragia Cerebral/patología , Hemorragia Cerebral/cirugía , Estudios de Cohortes , Diagnóstico por Imagen , Femenino , Predicción , Humanos , Hidrocefalia/diagnóstico , Hidrocefalia/patología , Hidrocefalia/cirugía , Lactante , Masculino , Análisis Multivariante , Estudios Retrospectivos
2.
AJNR Am J Neuroradiol ; 19(4): 791-5, 1998 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-9576676

RESUMEN

PURPOSE: We describe imaging features that are clues to the diagnosis of atretic cephaloceles and discuss clinical findings and a possible mechanism by which these lesions develop. METHODS: Eight children (five girls and three boys) ranging in age from 1 day to 3 years 4 months with midline subscalp lesions underwent radiologic examination with CT or MR imaging. In all cases, the lesions were surgically excised and subjected to pathologic examination. Imaging studies and medical records were reviewed retrospectively. RESULTS: Six of eight children had vertical embryonic positioning of the straight sinus with a prominent superior cerebellar cistern. A "spinning-top" configuration of the tentorial incisura, a "cigar-shaped" CSF tract within the interhemispheric fissure, fenestration of the superior sagittal sinus, and "peaking" of the tentorium were associated findings helpful in making this diagnosis. Two of the eight children had findings indistinguishable from focal dermoid, six were developmentally normal, one had mild motor delay, and one died at the age of 3 years. Pathologic examination revealed glial, meningeal (arachnoid), fibrous, and dermal elements. CONCLUSION: Characteristic findings on MR images and CT scans provide clues to the diagnosis of atretic cephalocele. However, even in the presence of abnormal imaging findings, these children may be developmentally normal.


Asunto(s)
Encefalocele/diagnóstico , Imagen por Resonancia Magnética , Lóbulo Parietal/diagnóstico por imagen , Lóbulo Parietal/patología , Tomografía Computarizada por Rayos X , Cerebelo/anomalías , Cerebelo/diagnóstico por imagen , Cerebelo/patología , Preescolar , Senos Craneales/embriología , Encefalocele/embriología , Encefalocele/cirugía , Femenino , Humanos , Lactante , Recién Nacido , Masculino , Lóbulo Parietal/cirugía , Estudios Retrospectivos
3.
Neurosurgery ; 34(3): 429-34; discussion 434, 1994 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-8190217

RESUMEN

The acquired descent of the cerebellar tonsils radiographically indistinguishable from Chiari I malformations has been previously reported. The relationship between lumbar shunting procedures for hydrocephalus and symptomatic Chiari malformations has been established. We report the cases of 10 children with lumboperitoneal shunts in whom previous radiographic studies had confirmed a normal hindbrain configuration. Seven of the 10 patients acquired tonsillar descent into the foramen magnum, detected by magnetic resonance imaging, whereas the others remained normal. Four of seven patients were symptomatic; two underwent the removal of the lumboperitoneal shunt and conversion to a ventriculoperitoneal shunt, and two underwent posterior fossa decompression. Further magnetic resonance imaging revealed that one of the two patients who underwent conversion shows ascent of the cerebellar tonsils. All four patients became asymptomatic less than 6 months after treatment. In this article, we discuss seven cases of acquired Chiari malformations and the complete reversal of an acquired Chiari malformation after surgical treatment, as documented by magnetic resonance imaging. Cases of asymptomatic acquired Chiari malformations are reported, including those resulting from shunting for intracranial hypertension without hydrocephalus. We conclude that a craniospinal pressure gradient creates a potential for cerebellar tonsil descent and recommend that ventriculoperitoneal shunting be performed in children with communicating hydrocephalus to avoid this potential complication. We also recommend annual surveillance of the cervicomedullary junction in children with lumboperitoneal shunting. Finally, if symptomatic tonsillar descent occurs from lumbar shunting, a trial conversion to ventriculoperitoneal shunting may eliminate the need for posterior fossa decompression.


Asunto(s)
Malformación de Arnold-Chiari/diagnóstico , Derivaciones del Líquido Cefalorraquídeo , Complicaciones Posoperatorias/diagnóstico , Adolescente , Adulto , Malformación de Arnold-Chiari/cirugía , Niño , Preescolar , Femenino , Humanos , Hidrocefalia/diagnóstico , Hidrocefalia/cirugía , Lactante , Presión Intracraneal/fisiología , Masculino , Complicaciones Posoperatorias/cirugía , Reoperación , Factores de Riesgo , Derivación Ventriculoperitoneal
4.
Neurosurgery ; 21(4): 532-6, 1987 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-3683787

RESUMEN

It has been suggested that concentrations of fibrin degradation products (FDPs) after head injury reflect the extent of brain tissue destruction. In addition, elevated FDP concentrations have been associated with the development of the adult respiratory distress syndrome (ARDS). Coagulation variables, including a FDP screen, were measured on the admission of 33 patients with severe closed head injury (Glasgow coma score 8 or less) to define the prognostic value of FDP concentrations. A Glasgow outcome score was assigned to each patient 6 months after injury, and those patients with higher FDP concentrations had poorer functional outcomes. This correlation of outcome with admission FDP concentration was statistically significant, as was the correlation between outcome and the admission Glasgow coma score. Of 22 patients with FDP concentrations of less than 64 micrograms/ml, only 1 developed early respiratory failure, whereas 9 of 11 patients with FDP concentrations of 64 micrograms/ml or more developed ARDS. These findings were not affected by the presence of multiple system trauma. FDP concentrations seem to have prognostic value similar to the Glasgow coma score and seem to identify those patients with head injury who are at high risk for ARDS.


Asunto(s)
Trastornos de la Coagulación Sanguínea/etiología , Traumatismos Craneocerebrales/complicaciones , Productos de Degradación de Fibrina-Fibrinógeno/metabolismo , Insuficiencia Respiratoria/etiología , Adulto , Trastornos de la Coagulación Sanguínea/metabolismo , Traumatismos Craneocerebrales/sangre , Traumatismos Craneocerebrales/fisiopatología , Femenino , Humanos , Masculino , Pronóstico , Estudios Prospectivos
5.
Neurosurgery ; 18(2): 180-5, 1986 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-3457288

RESUMEN

Upward projection of the cerebellar vermis through the tentorial hiatus is called upward vermal herniation (UVH). UVH is less common in clinical practice than uncal herniation. Even more uncommon is chronic vermal herniation and impaction in the tentorial hiatus. To illustrate this phenomenon, we present the clinical, radiological, and morphological features of vermal impaction in a patient with a postradiation osteosarcoma of the occipital bone. In spite of nearly total excision of the tumor pushing the cerebellum upward, his postoperative course was complicated by respiratory problems and an altered level of consciousness, finally resulting in death. His clinical status paralleled the computed tomographic (CT) demonstration of persistent obliteration of the supramesencephalic cistern. CT makes more reliable the detection and management of UVH, but a high index of suspicion is necessary for prevention of this complication.


Asunto(s)
Enfermedades Cerebelosas/etiología , Encefalocele/etiología , Hueso Occipital , Osteosarcoma/complicaciones , Neoplasias Craneales/complicaciones , Adulto , Enfermedades Cerebelosas/patología , Encefalocele/patología , Encefalocele/cirugía , Humanos , Masculino , Osteosarcoma/patología , Osteosarcoma/cirugía , Neoplasias Craneales/patología , Neoplasias Craneales/cirugía
6.
Neurosurgery ; 32(4): 541-5; discussion 545-6, 1993 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-8474644

RESUMEN

In the literature, clinical descriptions of sigmoid sinus thrombosis occurring after closed head injury in children are rare. One to 5 days after trauma to the back of the head, five children (aged 1 to 7 yr) presented with gait ataxia, vomiting, and headache. Trauma was mild in four children. Computed tomography of all the children, performed within 5 days after the injury, showed focal hyperdensity in the region of the left sigmoid sinus. Four children had extra-axial hyperdense collections along the left transverse sinus, and three had skull fractures adjacent to the left sigmoid sinus. Magnetic resonance imaging (MRI) of all the children, performed 2 to 6 days after injury, showed left sigmoid-sinus thrombosis and decreased flow or thrombosis within the lateral third of the left transverse sinus. All the children had MRI scans 4 to 6 weeks after their diagnosis and were followed up for 1 to 12 months. In four children whose symptoms subsided completely within 2 to 10 weeks, MRI showed recanalization of the sigmoid sinus within 4 to 6 weeks after injury. In one child whose symptoms resolved after 6 months, sigmoid-sinus thrombosis persisted with the formation of collateral flow. We conclude that traumatic sigmoid-sinus thrombosis should be suspected when a child has persistent or delayed gait ataxia and vomiting after injury to the back of the head. Computed tomography characteristically demonstrated focal hyperdensity within the sigmoid sinus that we term the dense sigmoid-sinus sign. Because the sinus recanalized and the symptoms subsided in most children within 6 weeks, we conclude that prophylactic medical or surgical intervention is not indicated.


Asunto(s)
Traumatismos Craneocerebrales/complicaciones , Trombosis de los Senos Intracraneales/etiología , Heridas no Penetrantes/complicaciones , Niño , Preescolar , Traumatismos Craneocerebrales/diagnóstico , Femenino , Humanos , Lactante , Imagen por Resonancia Magnética , Masculino , Enfermedades del Sistema Nervioso/etiología , Trombosis de los Senos Intracraneales/diagnóstico , Tomografía Computarizada por Rayos X , Heridas no Penetrantes/diagnóstico
7.
Neurosurgery ; 21(3): 347-51, 1987 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-3670580

RESUMEN

Syringomyelia, once regarded as a degenerative disease of adults, is now recognized to be a disorder usually associated with the Chiari malformation and occurring in patients of all ages. We have reviewed 47 patients with syringomyelia treated on the Neurosurgical Service at the Hospital for Sick Children during the years 1977 to 1985. Twelve of these patients had a Chiari I malformation, 30 had a Chiari II malformation, and 5 had an acquired Chiari malformation. Thirty-one of these patients were treated by decompression of the Chiari malformation and plugging of the obex, 5 were treated by a simple posterior fossa decompression, 9 were treated by shunting of the syringomyelic cavity, and 2 were treated by a combined decompression of the posterior fossa and shunting of the syrinx. The Gardner procedure (decompression of the Chiari malformation and plugging of the obex) was the procedure most commonly used in managing our group of patients and resulted in improvement in over 70% of patients.


Asunto(s)
Siringomielia/cirugía , Adolescente , Malformación de Arnold-Chiari/complicaciones , Malformación de Arnold-Chiari/diagnóstico , Malformación de Arnold-Chiari/cirugía , Derivaciones del Líquido Cefalorraquídeo , Niño , Preescolar , Femenino , Humanos , Hidrocefalia/complicaciones , Hidrocefalia/diagnóstico , Hidrocefalia/cirugía , Lactante , Masculino , Siringomielia/complicaciones , Siringomielia/diagnóstico
8.
Neurosurgery ; 23(6): 720-4, 1988 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-3216970

RESUMEN

Meningiomas have a wide range of biological potential and clinical behavior. Histological findings are helpful in recognizing the malignant potential of a given tumor, but often fail to correlate with gross features, liability of recurrence, and extent of associated cerebral edema. To find alternate approaches to improve the correlation between biological and clinical behavior, 20 meningiomas were studied by flow cytometry (FC), an assessment that has been applied to meningiomas previously. Such FC features as DNA index (DI) and proliferative index (PI, %G2 + %S) were correlated with size, location, brain invasion, associated edema, and recurrence. Tumors with severe edema had significantly higher PIs (19.5 +/- 4.1) than those with moderate (12.6 +/- 4.5) or minimal (8 +/- 0) edema (P less than 0.05). The PI was greater than 16 in those tumors that recurred (n = 3) or invaded the brain (n = 3). Six tumors were aneuploid (DI, 1.33 +/- 0.17; PI, 17.1 +/- 5.3). These were uniformly large when compared with the diploid tumors, which were more variable in size. All of the aneuploid tumors were associated with moderate to severe cerebral edema. Two partly psammomatous tumors with high PIs and foci of high cellularity suggesting recent growth were associated with severe edema. One of these exhibited brain invasion. These preliminary data indicate that FC may have a potential use in the clinical management of meningiomas.


Asunto(s)
Edema Encefálico/etiología , Neoplasias Encefálicas/patología , Meningioma/patología , Anciano , Anciano de 80 o más Años , Edema Encefálico/diagnóstico por imagen , Neoplasias Encefálicas/análisis , Neoplasias Encefálicas/diagnóstico por imagen , ADN de Neoplasias/análisis , Femenino , Citometría de Flujo , Humanos , Masculino , Meningioma/análisis , Meningioma/diagnóstico por imagen , Persona de Mediana Edad , Poliploidía , Radiografía
9.
Neurosurgery ; 22(2): 398-408, 1988 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-3281054

RESUMEN

Traumatic intracranial aneurysms in childhood are rare. To date, 67 well-documented cases in children have been reported. We present 2 additional cases and review the literature. Traumatic aneurysms can best be categorized based on mechanism of injury and location. Aneurysms secondary to penetrating trauma occur most commonly in teenage boys suffering gunshot wounds. Aneurysms secondary to nonpenetrating trauma occur at the skull base or in the periphery, with motor vehicle accidents and falls as the most common modes of injury. Skull base traumatic aneurysms most commonly involve the petrous, cavernous, or supraclinoid carotid artery and also show a predominance in teenage boys. Peripheral traumatic aneurysms can further be divided into distal anterior cerebral artery aneurysms secondary to trauma against the falcine edge and distal cortical artery aneurysms associated with an overlying skull fracture. Peripheral traumatic aneurysms tend to occur in younger patients with a less marked male predominance. Two-thirds of the patients suffered symptomatic aneurysmal hemorrhage, with an associated mortality rate of 31%. The clinical presentation, diagnosis, and treatment of traumatic intracranial aneurysms are discussed.


Asunto(s)
Traumatismos Craneocerebrales/complicaciones , Aneurisma Intracraneal/etiología , Adolescente , Enfermedades de las Arterias Carótidas/diagnóstico por imagen , Enfermedades de las Arterias Carótidas/etiología , Enfermedades de las Arterias Carótidas/cirugía , Angiografía Cerebral , Preescolar , Femenino , Humanos , Aneurisma Intracraneal/diagnóstico por imagen , Aneurisma Intracraneal/cirugía , Masculino
10.
J Neurosurg ; 82(5): 780-5, 1995 May.
Artículo en Inglés | MEDLINE | ID: mdl-7714602

RESUMEN

Loculated hydrocephalus remains a difficult neurosurgical problem and endoscopes designed to navigate through the ventricular system provide a new option for treatment. The authors review their experience, during the period March 1990 to June 1993, using a steerable fiberscope in 34 cases of loculated hydrocephalus to evaluate the efficacy of endoscopic cyst fenestration. The goals of treatment were to control hydrocephalus, simplify preexisting shunt systems, and reduce operative morbidity. Endoscopic cyst fenestrations reduced the shunt revision rate from 3.04 per year prior to endoscopy to 0.25 per year after the procedure, during a follow-up period ranging from 8 to 45 months, mean 26 months. However, eight patients (23.5%) required 14 repeat operations to control loculated hydrocephalus. After endoscopy, patients with multiloculated hydrocephalus had a nearly fivefold increased risk (relative risk 4.85) for shunt malfunction and more than a twofold increased risk (relative risk 2.43) for cyst recurrence versus patients with uniloculated hydrocephalus. Similarly, six (50%) of 12 patients shunted prior to endoscopy required a repeat endoscopic procedure (relative risk 5.56). Although repeat endoscopic procedures may be required to control hydrocephalus, endoscopic cyst fenestration avoided placement of a shunt in seven (33%) of 21 patients with uniloculated hydrocephalus. One patient, encountered early in the authors' experience, required a craniotomy for fenestration of multiple ventricular cysts. Endoscopic complications included cerebrospinal fluid leakage in one case and ventriculitis in another. The authors conclude that endoscopic treatment of loculated hydrocephalus is a safe, minimally invasive technique that should be considered as the initial treatment option.


Asunto(s)
Endoscopía/métodos , Hidrocefalia/terapia , Técnicas Estereotáxicas , Adolescente , Adulto , Anciano , Encefalopatías/complicaciones , Encefalopatías/cirugía , Ventrículos Cerebrales/cirugía , Derivaciones del Líquido Cefalorraquídeo , Niño , Preescolar , Quistes/complicaciones , Quistes/cirugía , Endoscopía/efectos adversos , Femenino , Estudios de Seguimiento , Humanos , Hidrocefalia/diagnóstico por imagen , Hidrocefalia/etiología , Lactante , Recién Nacido , Masculino , Persona de Mediana Edad , Reoperación , Tomografía Computarizada por Rayos X
11.
J Neurosurg ; 81(1): 37-42, 1994 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-7515955

RESUMEN

The role of hemispherectomy in treating holohemispheric hemimegaloencephaly, a unilateral brain malformation, is still not well defined. The authors describe the cases of five infants presenting with intractable seizures, progressive neurological deficits, and severe developmental delay. Electroencephalography (EEG) showed generalized polyspikes from the megaloencephalic hemisphere and progressive slowing on the opposite side in all children; contralateral seizure spikes occurred in three children. Three of the five children underwent hemispherectomy for intractable seizures before 2 years of age, after which the seizures subsided completely in two children and improved remarkably in the third. Preoperative Wada testing proved useful in evaluating pharmacologically the effect of hemispherectomy on contralateral polyspikes. Postoperative EEG revealed the absence of polyspikes in the operated hemisphere and decreased slowing on the contralateral side. Psychomotor development in the surgically treated infants exceeded that of the children not undergoing hemispherectomy. Of the two children treated medically, one died at 4 years of age in status epilepticus and the other (now 5 years old) has frequent seizures and severe developmental delay. Based on these results, hemispherectomy appears to be a useful procedure for controlling seizures and improving psychomotor development in children with hemimegaloencephaly involving the entire hemisphere. Surgery in infancy can prevent or minimize seizure foci and encephalopathic changes that may develop in the contralateral hemisphere. Staging the procedure and exercising meticulous hemostasis make surgery relatively safe in infants who otherwise may have significant blood loss associated with increased blood flow to the megaloencephalic hemisphere.


Asunto(s)
Encéfalo/anomalías , Encéfalo/cirugía , Anticonvulsivantes/uso terapéutico , Encéfalo/patología , Derivaciones del Líquido Cefalorraquídeo , Niño , Trastornos de la Conducta Infantil/etiología , Trastornos de la Conducta Infantil/cirugía , Desarrollo Infantil , Preescolar , Discapacidades del Desarrollo/etiología , Discapacidades del Desarrollo/cirugía , Electroencefalografía , Epilepsia Tónico-Clónica/tratamiento farmacológico , Epilepsia Tónico-Clónica/etiología , Epilepsia Tónico-Clónica/cirugía , Femenino , Estudios de Seguimiento , Humanos , Lactante , Recién Nacido , Masculino , Destreza Motora , Examen Neurológico , Desempeño Psicomotor , Convulsiones/tratamiento farmacológico , Convulsiones/etiología , Convulsiones/cirugía , Resultado del Tratamiento
12.
J Neurosurg ; 80(4): 732-5, 1994 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-8151354

RESUMEN

The case is reported of meningioangiomatosis of the brain stem in a 3 1/2-year-old girl who suffered from vomiting, left facial weakness, difficulty in swallowing, and ataxia. This is believed to be the first reported case of meningioangiomatosis in the brain stem. Computerized tomography showed an intensely enhancing hyperdense mass in the left restiform body. Magnetic resonance imaging revealed that the lesion was isointense to gray matter on the T1-weighted image and hypointense on the T2-weighted image, with a surrounding zone of high T2 signal and intense enhancement. Angiography was normal. Surgical exploration demonstrated an intramedullary firm mass that was partially resected. Histologically, the mass consisted of a low-grade lesion of meningeal origin with spindle cells in a whorling pattern that were occasionally focused around small vessels. On 2-year follow-up imaging, the lesion remains unchanged in size. Certain particularities of this lesion are discussed in the context of the literature.


Asunto(s)
Tronco Encefálico , Neoplasias Meníngeas , Meningioma , Preescolar , Femenino , Humanos , Imagen por Resonancia Magnética , Neoplasias Meníngeas/diagnóstico , Neoplasias Meníngeas/patología , Neoplasias Meníngeas/cirugía , Meningioma/diagnóstico , Meningioma/patología , Meningioma/cirugía , Tomografía Computarizada por Rayos X
13.
J Neurosurg ; 87(5): 677-81, 1997 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-9347974

RESUMEN

The surgical treatment of transsphenoidal cephaloceles in children is controversial. Reduction and repair via a transcranial approach are associated with high postoperative rates of morbidity, mortality, and hypothalamic dysfunction. In this study, four patients, aged 3 to 35 months at surgery, underwent successful transpalatal repair of two encephaloceles and two meningoceles. Two patients presented with nasal obstruction in infancy, one presented with unexplained meningitis, and in one patient the lesion was found incidentally during evaluation for seizures. Two children had median cleft face syndrome, another had an associated Arnold-Chiari type I malformation, and the fourth had no other cranial abnormalities. All patients underwent preoperative evaluation including magnetic resonance (MR) imaging. Auditory, ophthalmological, genetic, endocrinological, or other evaluation was undertaken as indicated. Lesions were approached through the median raphe of the hard and soft palates. All cephaloceles were easily visualized and dissected after division of the nasal palatal mucosa. The dural sac and its contents were reduced by surface coagulation after division and dissection of the overlying mucosa. Once reduced, the bone defect was obliterated in three of four patients. The dura was not opened and anomalous neural elements were not resected. At follow-up evaluation, all patients demonstrated resolution of preoperative symptoms without evidence of infection or lasting morbidity. Follow-up MR imaging showed reduction in all cases. The authors conclude that this transpalatal approach is safe and reliable for the treatment of transsphenoidal cephaloceles in young children.


Asunto(s)
Encefalocele/cirugía , Procedimientos Neuroquirúrgicos/métodos , Hueso Paladar/cirugía , Seno Esfenoidal/anomalías , Seno Esfenoidal/cirugía , Preescolar , Encefalocele/diagnóstico , Encefalocele/fisiopatología , Femenino , Humanos , Lactante , Recién Nacido , Imagen por Resonancia Magnética , Masculino , Resultado del Tratamiento
14.
J Neurosurg ; 88(1): 51-6, 1998 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-9420072

RESUMEN

OBJECT: Radiation is a common treatment modality for pediatric brain tumors. The authors present a retrospective review of six children who developed cerebral cavernous malformations after they underwent radiation treatment for central nervous system (CNS) neoplasia and propose two possible models to explain the formation of cavernous malformations. METHODS: Three boys, aged 13, 9, and 17 years, suffered intracerebral hemorrhages from cerebral cavernous malformations 87, 94, and 120 months, respectively, after they received whole-brain radiation therapy (WBRT) for acute lymphocytic leukemia. A 10-year-old girl and a 19-year-old man developed temporal lobe cavernous malformations 46 and 48 months, respectively, after they received radiation therapy for posterior fossa astrocytomas. A 12-year-old girl developed a temporal lobe cavernous malformation 45 months after WBRT was administered for a medulloblastoma. In all of these cases the cavernous malformation appeared in the irradiated field, was not known to be present prior to radiation therapy, and developed after a latency period following treatment. The incidence of cavernous malformations in these patients suggests that children who undergo radiation therapy of the brain may have an increased risk of hemorrhage. CONCLUSIONS: Two possible models may explain the formation of cavernous malformations following brain radiation in these patients. First, the cavernous malformations may form de novo in response to the radiation. Second, the cavernous malformations may have been present, but radiographically occult, at the time of radiation therapy and may have hemorrhaged in response to the radiation. The authors conclude that cavernous malformations may develop after brain radiation and propose a possible mechanism for this formation.


Asunto(s)
Neoplasias Encefálicas/radioterapia , Seno Cavernoso/efectos de la radiación , Malformaciones Arteriovenosas Intracraneales/etiología , Adolescente , Astrocitoma/radioterapia , Seno Cavernoso/patología , Niño , Preescolar , Femenino , Humanos , Malformaciones Arteriovenosas Intracraneales/patología , Imagen por Resonancia Magnética , Masculino , Meduloblastoma/radioterapia , Leucemia-Linfoma Linfoblástico de Células Precursoras/radioterapia , Radioterapia Adyuvante/efectos adversos
15.
J Neurosurg ; 81(2): 174-8, 1994 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-8027797

RESUMEN

It is still not determined which is the best surgical option for third ventricle colloid cysts. Since 1990, the authors have used a steerable fiberscope to remove colloid cysts in seven patients and have performed microsurgery via a transcallosal approach in eight patients. The two techniques were compared for operating time, length of hospital stay, incidence of complications, recurrence, and hydrocephalus, and days spent recuperating before return to work to determine if endoscopic removal of colloid cysts is a safe and effective alternative to microsurgery. Statistical analysis was adjusted for age, sex, and presenting symptoms. Microsurgical cases averaged 206 minutes of operating time whereas endoscopic cases averaged 127 minutes (p = 0.01). For combined days spent in the intensive care unit and on the ward, the patients averaged 9.5 days after microsurgery and 4 days after endoscopy (p = 0.05). Postoperative complications occurred in five of eight patients after microsurgery and in one of seven patients after endoscopy (p = 0.09); complications were transient and primarily related to short-term memory loss. In all patients, preoperative symptoms resolved and the cysts have not recurred. Postoperatively, one patient required a ventriculoperitoneal shunt after microsurgery but all patients were shunt-independent after endoscopy. Patients returned to work an average of 59 days after discharge following microsurgery compared with an average of 26 days after endoscopy (p = 0.05). Compared with transcallosal microsurgery for the removal of colloid cysts, these preliminary results show that a steerable endoscope reduced operating time and that patients spent fewer days in the hospital and returned to work sooner after endoscopy.


Asunto(s)
Ventrículos Cerebrales/cirugía , Cuerpo Calloso/cirugía , Quistes/cirugía , Endoscopía , Microcirugia , Adolescente , Adulto , Anciano , Encefalopatías/cirugía , Cuidados Críticos , Endoscopía/efectos adversos , Endoscopía/métodos , Femenino , Humanos , Hidrocefalia/etiología , Incidencia , Coagulación con Láser , Tiempo de Internación , Masculino , Trastornos de la Memoria/etiología , Memoria a Corto Plazo , Microcirugia/efectos adversos , Microcirugia/métodos , Persona de Mediana Edad , Alta del Paciente , Recurrencia , Factores de Tiempo
16.
Surg Neurol ; 24(6): 668-70, 1985 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-4060048

RESUMEN

A patient with adult-onset diabetes mellitus developed an oculomotor palsy with pupillary sparing. Five days after her initial evaluation, she presented in a confused state with a complete oculomotor palsy. Computed cranial tomography revealed a chronic subdural hematoma. We recommend that noninvasive radiographic intracranial investigation be considered in elderly patients with adult-onset diabetes mellitus who present with headache and pupil-sparing oculomotor palsy.


Asunto(s)
Hematoma Subdural/complicaciones , Oftalmoplejía/etiología , Anciano , Enfermedad Crónica , Complicaciones de la Diabetes , Femenino , Hematoma Subdural/diagnóstico , Humanos , Oftalmoplejía/diagnóstico , Pupila
17.
Surg Neurol ; 25(3): 276-8, 1986 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-3945909

RESUMEN

Intracranial air secondary to craniocerebral trauma is not uncommon. Computed tomography scanning may show the air within specific intracranial compartments. We report a case of air within the superior sagittal sinus visualized with computed tomography and documented at operation.


Asunto(s)
Lesiones Encefálicas/complicaciones , Senos Craneales , Traumatismos Craneocerebrales/complicaciones , Embolia Aérea/etiología , Heridas por Arma de Fuego/complicaciones , Adulto , Lesiones Encefálicas/cirugía , Senos Craneales/diagnóstico por imagen , Senos Craneales/cirugía , Traumatismos Craneocerebrales/cirugía , Embolia Aérea/diagnóstico por imagen , Embolia Aérea/cirugía , Humanos , Masculino , Tomografía Computarizada por Rayos X , Heridas por Arma de Fuego/cirugía
18.
Minim Invasive Neurosurg ; 50(6): 313-7, 2007 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-18210351

RESUMEN

OBJECTIVE: Questions of recurrence and inadequacy of follow-up length persist regarding endoscopic treatment of colloid cysts. In this retrospective review, we report our long-term follow-up during a 13-year period in 35 patients who underwent endoscopic resection of colloid cysts. METHODS: The 19 males and 16 females (age range 14 to 58 years, mean 35.9 years) who had symptomatic colloid cysts that ranged in size from 5 mm to 4 cm underwent endoscopic resection in the period from 1991 to 2004. RESULTS: Of 2 patients who developed recurrences at 5.9 years and 4.3 years (1 and 6 mm, respectively) both remain asymptomatic. The rate of late asymptomatic recurrence in this series is 6.3%. Three endoscopic resections were converted to an open craniotomy. Three operative complications occurred (i.e., introducer tract hemorrhage, thalamic stroke secondary to thermal injury, epidural hematoma that required evacuation). Four patients noted minimal short-term memory loss without interference in daily living. Of 3 patients with shunts preoperatively, all have no evidence of hydrocephalus after shunt removal. Two patients have asymptomatic ventriculomegaly. Prophylactic anticonvulsants were not prescribed and no seizures were reported. No infections were recorded with antibiotic administration preoperatively, and 24 hours postoperatively. CONCLUSIONS: Our series represents the longest follow-up (mean of 7.8 years) of colloid cysts after endoscopic resection. We now use this technique as the first line of treatment for colloid cysts. The risk of recurrence is minimal with gross total resection and/or coagulation of the cyst wall.


Asunto(s)
Quistes del Sistema Nervioso Central/cirugía , Neoplasias del Ventrículo Cerebral/cirugía , Endoscopía/estadística & datos numéricos , Procedimientos Neuroquirúrgicos/estadística & datos numéricos , Tercer Ventrículo/cirugía , Adolescente , Adulto , Quistes del Sistema Nervioso Central/patología , Quistes del Sistema Nervioso Central/fisiopatología , Neoplasias del Ventrículo Cerebral/patología , Neoplasias del Ventrículo Cerebral/fisiopatología , Craneotomía/normas , Craneotomía/estadística & datos numéricos , Endoscopía/efectos adversos , Endoscopía/métodos , Femenino , Hematoma Epidural Craneal/etiología , Hematoma Epidural Craneal/patología , Hematoma Epidural Craneal/fisiopatología , Humanos , Hidrocefalia/etiología , Hidrocefalia/prevención & control , Hidrocefalia/cirugía , Hemorragias Intracraneales/etiología , Hemorragias Intracraneales/patología , Hemorragias Intracraneales/fisiopatología , Masculino , Trastornos de la Memoria/etiología , Trastornos de la Memoria/fisiopatología , Persona de Mediana Edad , Procedimientos Neuroquirúrgicos/efectos adversos , Procedimientos Neuroquirúrgicos/métodos , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/patología , Complicaciones Posoperatorias/fisiopatología , Recurrencia , Estudios Retrospectivos , Enfermedades Talámicas/etiología , Enfermedades Talámicas/patología , Enfermedades Talámicas/fisiopatología , Tercer Ventrículo/patología , Tercer Ventrículo/fisiopatología , Tiempo , Factores de Tiempo , Resultado del Tratamiento
19.
Minim Invasive Neurosurg ; 49(5): 317-20, 2006 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-17163349

RESUMEN

BACKGROUND: Major sources of morbidity and mortality in patients with tuberous sclerosis who develop subependymal giant cell astrocytomas (SEGAs) relate to tumor growth and resultant hydrocephalus. We describe a modification of a specialized minimal access resection technique in which an operative corridor is formed with balloon dilation over the course of a week prior to tumor resection. METHODS: Three patients with tuberous sclerosis who had an enlarging SEGA and concomitant hydrocephalus underwent surgical resection with this modified technique. A frontal craniotomy was performed and the optimal trajectory for tumor resection was confirmed by image guidance. After initial insertion of the deflated balloon into the ventricle and removal of the peel-away sheath, inflation of the balloon with a 1-mL saline injection sealed the tract. Additional 1-mL saline injections were continued during the next week until the balloon reached a 15-mm diameter, thus creating the operative corridor. One week after the first operation, the balloon was deflated and removed, and the patient underwent tumor resection via the newly formed operative corridor. RESULTS: Three patients with tuberous sclerosis underwent gross total resections of SEGAs and experienced subsequent resolution of ventricular dilation. Postoperative imaging confirmed minimal cortical disruption. CONCLUSIONS: Use of balloon dilation for the gradual formation of an operative corridor eliminated the need for additional retraction during SEGA resection, potentially decreasing injury to the surrounding neural tissue. In our three patients, the dilation tract retained its integrity during the operation and had sealed completely on postoperative imaging.


Asunto(s)
Astrocitoma/cirugía , Neoplasias Encefálicas/cirugía , Cateterismo/métodos , Craneotomía/métodos , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Esclerosis Tuberosa/cirugía , Adolescente , Astrocitoma/etiología , Neoplasias Encefálicas/etiología , Niño , Preescolar , Femenino , Humanos , Hidrocefalia/prevención & control , Masculino , Procedimientos Neuroquirúrgicos/métodos , Tomografía Computarizada por Rayos X , Esclerosis Tuberosa/complicaciones
20.
Pediatr Neurosurg ; 27(6): 292-5, 1997 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-9655143

RESUMEN

Chronic hematomas are a common problem during infancy and usually occur as the consequence of trauma. They tend to enlarge and are often managed successfully with repeated subdural taps. In patients with collections that fail to respond to percutaneous drainage, the choice of operative management, including burr hole evacuation, shunting, or craniotomy, remains controversial. A new technique, called endoscopic washout, was successfully used in 7 children under the age of 2 years who presented with irritability, vomiting, seizures, and rapid head growth. Preoperative computerized tomography (CT) scans demonstrated enlarging, bilateral, chronic subdural collections; these failed to respond to repeated percutaneous taps over 10 days. With the patient positioned supine, bilateral linear incisions were made anterior to the coronal suture in the midpupillary lines and burr holes were placed. After the dura and outer membrane were opened and coagulated with bipolar cautery, a 4-mm steerable fiberscope was introduced into the subdural space to visualize the collections, evacuate any residual clot, and continuously irrigate the space with lactated Ringer's solution warmed to physiologic temperature. No bridging vessels or synechiae were violated; nitrous oxide and hyperventilation were discontinued before removing the fiberscope. The subdural space was irrigated again prior to closure. At follow-up (range 18 months to 8 years), CT scans showed reexpansion of the brain and no reaccumulation of the hematomas. We conclude that the endoscopic washout is a safe, uncomplicated treatment for chronic subdural hematomas in infants; is more effective than treatment with conventional burr holes alone, and eliminates the need for shunting or craniotomy.


Asunto(s)
Endoscopios , Hematoma Subdural/cirugía , Trepanación/instrumentación , Enfermedad Crónica , Hematoma Subdural/diagnóstico por imagen , Hematoma Subdural/etiología , Humanos , Lactante , Masculino , Recurrencia , Irrigación Terapéutica/instrumentación , Tomografía Computarizada por Rayos X , Resultado del Tratamiento
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