Detalles de la búsqueda
1.
Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability.
Pharmacogenet Genomics
; 34(4): 91-104, 2024 Jun 01.
Artículo
Inglés
| MEDLINE | ID: mdl-38682317
2.
LDLR and PCSK9 3´UTR variants and their putative effects on microRNA molecular interactions in familial hypercholesterolemia: a computational approach.
Mol Biol Rep
; 50(11): 9165-9177, 2023 Nov.
Artículo
Inglés
| MEDLINE | ID: mdl-37776414
3.
Population-scale predictions of DPD and TPMT phenotypes using a quantitative pharmacogene-specific ensemble classifier.
Br J Cancer
; 123(12): 1782-1789, 2020 12.
Artículo
Inglés
| MEDLINE | ID: mdl-32973300
4.
Single-nucleotide polymorphisms related to vitamin D metabolism and severity or mortality of COVID-19: A systematic review and meta-analysis.
Gene
; 906: 148236, 2024 May 15.
Artículo
Inglés
| MEDLINE | ID: mdl-38316264
5.
Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia.
Chem Phys Lipids
; 257: 105348, 2023 11.
Artículo
Inglés
| MEDLINE | ID: mdl-37827478
6.
Effects of PCSK9 missense variants on molecular conformation and biological activity in transfected HEK293FT cells.
Gene
; 851: 146979, 2023 Jan 30.
Artículo
Inglés
| MEDLINE | ID: mdl-36261084
7.
LDLR missense variants disturb structural conformation and LDLR activity in T-lymphocytes of Familial hypercholesterolemia patients.
Gene
; 853: 147084, 2023 Feb 15.
Artículo
Inglés
| MEDLINE | ID: mdl-36464169
8.
In silico analysis of upstream variants in Brazilian patients with Familial hypercholesterolemia.
Gene
; 849: 146908, 2023 Jan 15.
Artículo
Inglés
| MEDLINE | ID: mdl-36167182
9.
Identification of pathogenic variants in the Brazilian cohort with Familial hypercholesterolemia using exon-targeted gene sequencing.
Gene
; 875: 147501, 2023 Jul 30.
Artículo
Inglés
| MEDLINE | ID: mdl-37217153
10.
Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts.
Pharmacol Rep
; 74(1): 47-66, 2022 Feb.
Artículo
Inglés
| MEDLINE | ID: mdl-34403130
11.
Pharmacogenomics of Antihypertensive Drugs in Brazil: Recent Progress and Clinical Implications.
Endocr Metab Immune Disord Drug Targets
; 22(13): 1263-1275, 2022.
Artículo
Inglés
| MEDLINE | ID: mdl-34951375
12.
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.
Pharmaceutics
; 14(5)2022 Apr 27.
Artículo
Inglés
| MEDLINE | ID: mdl-35631530
13.
Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients.
Mol Diagn Ther
; 25(6): 735-755, 2021 11.
Artículo
Inglés
| MEDLINE | ID: mdl-34357562
14.
Functional analysis of PCSK9 3'UTR variants and mRNA-miRNA interactions in patients with familial hypercholesterolemia.
Epigenomics
; 13(10): 779-791, 2021 05.
Artículo
Inglés
| MEDLINE | ID: mdl-33899508
15.
Late response to rosuvastatin and statin-related myalgia due to SLCO1B1, SLCO1B3, ABCB11, and CYP3A5 variants in a patient with Familial Hypercholesterolemia: a case report.
Ann Transl Med
; 9(1): 76, 2021 Jan.
Artículo
Inglés
| MEDLINE | ID: mdl-33553369
16.
Genomics, epigenomics and pharmacogenomics of familial hypercholesterolemia (FHBGEP): A study protocol.
Res Social Adm Pharm
; 17(7): 1347-1355, 2021 07.
Artículo
Inglés
| MEDLINE | ID: mdl-33129683
17.
Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability
Pharmacogenet. genomics
; 34(4): 91-104, jun.2024.
Artículo
Inglés
| CONASS, SES-SP, SES SP - Instituto Dante Pazzanese de Cardiologia, SES-SP | ID: biblio-1552919
18.
Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia
Chem. Phys. lipids
; 257: 105348, nov.2023. ilus
Artículo
Inglés
| CONASS, SES-SP, SES SP - Instituto Dante Pazzanese de Cardiologia, SES-SP | ID: biblio-1524856
19.
LDLR and PCSK9 3´UTR variants and their putative effects on microRNA molecular interactions in familial hypercholesterolemia: a computational approach
Mol. Biol. reports
; 50: 9165-9177, set.2023. ilus
Artículo
Inglés
| CONASS, SES-SP, SES SP - Instituto Dante Pazzanese de Cardiologia, SES-SP | ID: biblio-1525357
20.
Confounding Variables and the Performance of Triggers in Detecting Unreported Adverse Drug Reactions.
Clin Ther
; 39(4): 686-696, 2017 Apr.
Artículo
Inglés
| MEDLINE | ID: mdl-27913030