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J Drugs Dermatol ; 18(10): 1002-1004, 2019 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-31584778

RESUMEN

Lanolin alcohol is a high cholesterol containing naturally derived material used as a skin protectant in wound healing petrolatum-based ointments. It is a highly purified fraction of lanolin wool wax that has been identified as a possible cause of allergic contact dermatitis. This 3-center study enrolled 499 subjects who underwent a variety of in-office surgical procedures followed by application of a wound healing ointment containing lanolin alcohol without antibiotics. No allergic contact dermatitis was identified in the 499 subjects who completed the study. The lack of allergic contact dermatitis observed may be due to the proprietary highly purified lanolin alcohol utilized in the study formulation. This is not the lanolin alcohol preparation found on the standard dermatology patch test tray. Not all lanolin alcohols are equal. This is an important consideration when examining the reported incidence of allergic contact dermatitis to lanolin alcohol and the absence of allergic contact dermatitis demonstrated in this research. J Drugs Dermatol. 2019;18(10):1002-1004.


Asunto(s)
Dermatitis Alérgica por Contacto/epidemiología , Lanolina/efectos adversos , Vaselina/efectos adversos , Herida Quirúrgica/tratamiento farmacológico , Adolescente , Adulto , Anciano , Estudios de Cohortes , Dermatitis Alérgica por Contacto/etiología , Femenino , Humanos , Lanolina/administración & dosificación , Masculino , Persona de Mediana Edad , Bases Oleosas , Pomadas , Vaselina/administración & dosificación , Prevalencia , Resultado del Tratamiento , Cicatrización de Heridas/efectos de los fármacos , Adulto Joven
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