RESUMEN
The paper shows the role of biliary dysfunction in the formation of biliary sludge. Found that among all motor dysfunction themost common is reduction of contractile function of the gallbladder (in 63.3% of cases), which is combined with 73.2% Oddi's sphincter hypertonus. T The combination of ursodeoxycholic acid (UDCA) with mebeverine has a better effect than monotherapy with UDCA, as increases the frequency of relief of biliary dyspepsia symptoms, normalizes the biliary tract functional status and 95% of cases leads to the elimination of biliary sludge.
Asunto(s)
Discinesia Biliar/complicaciones , Colagogos y Coleréticos/uso terapéutico , Cálculos Biliares/etiología , Fenetilaminas/uso terapéutico , Ácido Ursodesoxicólico/uso terapéutico , Adulto , Bilis , Discinesia Biliar/diagnóstico , Discinesia Biliar/tratamiento farmacológico , Colagogos y Coleréticos/administración & dosificación , Quimioterapia Combinada , Femenino , Cálculos Biliares/tratamiento farmacológico , Humanos , Masculino , Fenetilaminas/administración & dosificación , Disfunción del Esfínter de la Ampolla Hepatopancreática/complicaciones , Disfunción del Esfínter de la Ampolla Hepatopancreática/diagnóstico , Disfunción del Esfínter de la Ampolla Hepatopancreática/tratamiento farmacológico , Ácido Ursodesoxicólico/administración & dosificaciónRESUMEN
The article provides data of the pharmacoeconomic analysis (cost/effectiveness) of treatment of peptic ulcer, ulcerative colitis, Crohn's disease, gastroesophageal reflux disease, biliary sludge and cholelithiasis. It was shown that the most appropriate treatment scheme is one that characterized by lower costs per unit of effectiveness. Analysis of cost/effectiveness can give an economic assessment of clinical efficacy, compare alternative treatments and help to choose the method by which the efficiency increases faster than the level of costs.