Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Resultados 1 - 9 de 9
Filtrar
3.
Am J Hematol ; 21(4): 415-8, 1986 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-3953560

RESUMEN

The presence of teardrop-shaped red cells in peripheral blood has traditionally been felt to reflect altered marrow architecture, namely myelofibrosis. We evaluated two patients with splenomegaly, moderately severe hemolytic anemia due to warm-reactive IgG anti-red cell autoantibody, and bone marrow erythroid hyperplasia without myelofibrosis. A striking predominance of teardrop-shaped red cells was noted upon examination of their blood films. Removal of a spleen containing extramedullary hematopoiesis in one and resolution of splenomegaly in the other were accompanied by disappearance of these cells. Our observations support a role for the spleen and for extramedullary hematopoiesis in the pathogenesis of this distinctive red cell morphologic abnormality.


Asunto(s)
Anemia Hemolítica Autoinmune/sangre , Eritrocitos Anormales/patología , Bazo/fisiopatología , Anemia Hemolítica Autoinmune/diagnóstico , Anemia Hemolítica Autoinmune/fisiopatología , Médula Ósea/patología , Diagnóstico Diferencial , Femenino , Hematopoyesis , Humanos , Masculino , Persona de Mediana Edad , Mielofibrosis Primaria/diagnóstico , Bazo/patología , Esplenectomía
SELECCIÓN DE REFERENCIAS
Detalles de la búsqueda