Dirofilariasis of the breast in france.

Sections of a nongravid adult female Dirofilaria, probably D. repens, were found within a subcutaneous nodule excised from the breast of a 45-year-old Frenchwoman. This is the 29th case of D. repens in man in France and the first in which the parasite was located in the breast. The patient apparently acquired the infection while vacationing in the southeastern Mediterranean region of the country.

[Malignant histiocytosis simulating histiocytosis with massive sinusal lymphadenopathy, on the first lymph node biopsy (author's transl)]. / Histiocytose maligne, simulant une histiocytose sinusale massive hémophagocytaire, sur une biopsie ganglionnaire initiale.

The case of a 36 year old man who presented prominent bilateral cervical lymphadenopathies is reported. The diagnosis of sinus histiocytosis with massive lymphadenopathy (Rosai and Dorfman, 1969) was retained on account of a massive hyperplasia of foamy histiocytes with PAS + inclusions, lipidic storage and hemocytophagy in the sinuses and cords of the lymph nodes. The patient died after 34 months evolution. At the autopsy an important proliferation by large atypical sometimes multinucleated cells in the lymph nodes, liver, bone and spleen was found, as observed in malignant histiocytosis. The ultrastructural study confirmed the histiocytic nature of the cells. The interest of immunohistochemical studies on paraffin embedded material with characterization of tumor histiocytes with lysozyme and alpha 1 antichymotrypsin is discussed. This report described an unusual form of malignant histiocytosis simulating on his early phase sinus histiocytosis with massive lymphadenopathy.

[Thymic carcinoid tumors. A clinico-anatomic study of 3 cases]. / Carcinoïdes du thymus. Etude anatomo-clinique de 3 cas.

The carcinoid tumour of the thymus was first detailed by Rosai in 1972. The authors describe three cases of this tumour with particular reference to their histogenesis. It appears to be a tumour predominantly affecting males with an often unfavourable, though slow, progression. Some pathological associations are frequent and characteristic. In one third of cases there is an associated endocrine neoplasia. As a rule the tumour is sited in the anterior mediastinum. The precise diagnosis rests on histochemical criteria (specific granulations). These carcinoids are tumours of the APUD system of endodermal origin. The treatment is surgical.

[Multicentric granular cell tumor of the tracheobronchial tree]. / Tumeur à cellules granuleuses multicentrique de l'arbre tracheéo-bronchique.

The authors describe a case of multicentric endotracheobronchial myoblastoma with one endotracheal localization and two bronchial localizations. The patient underwent resection of the inferior lobe of the left lung. The tracheal tumor was not removed. Two years after surgery the patient is doing well. Several biopsy specimens have been removed from the tracheal tumor which has remained unchanged. Cases such as ours are very uncommon. Therapeutic decisions may be difficult.

[Bronchial granular cell tumor. Apropos of 2 cases]. / Tumeur à cellules granuleuses bronchique. A propos de deux cas.

The authors report two new cases of bronchial granular cell tumour, a site which remains relatively rare. One of these cases was studied from the point of view of histoenzymology and ultrastructure. The appearances seen were identical to those seen in the literature. They lead to the problem of the histogenetics of the lesion, various morphological factors favouring a Schwann cell origin, whilst the presence of "transitional" cells is more in favour of a mesenchymatous origin, or at least the role of mesenchymatous cells in the development of these lesions.