RESUMEN
Malnutrition leads to adverse effects and may worsen clinical outcome. Surgery as a stress factor activates pathological reactions changing metabolism structure. The aim of this study was to evaluate changes of protein metabolism in patients after elective neurosurgical operation. 24 patients were prepared for elective surgery and were enrolled in this study. Evaluation of each patient included: measurement of anthropometric indices--height, weight, arm circumference and the triceps skinfold thickness, the definition of protein loss by determining the loss of nitrogen in the urine, assessment of protein catabolism, determining the violations of nutritional status upon the base of laboratory parameters. During the course of the conducted investigation significant (p < 0.05) decrease in the indices of total protein, albumin, transferrin and the absolute numbers of lymphocytes in the postoperative period was revealed. All the patients developed severe protein catabolism. It became clear that uncomplicated elective surgical intervention, together with the adopted scheme of the nutritional therapy leads to severe protein catabolism in all patients.
Asunto(s)
Albúminas/metabolismo , Neoplasias Encefálicas/cirugía , Nitrógeno/orina , Complicaciones Posoperatorias , Desnutrición Proteico-Calórica , Transferrina/metabolismo , Adulto , Neoplasias Encefálicas/sangre , Neoplasias Encefálicas/orina , Femenino , Humanos , Recuento de Linfocitos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/sangre , Complicaciones Posoperatorias/tratamiento farmacológico , Complicaciones Posoperatorias/orina , Desnutrición Proteico-Calórica/sangre , Desnutrición Proteico-Calórica/dietoterapia , Desnutrición Proteico-Calórica/etiología , Desnutrición Proteico-Calórica/orinaRESUMEN
The effect of ataralgesia (diazepam and fentanyl anesthesia) on cerebral blood flow and metabolism has been studied in 9 patients with arterial aneurysms of cerebral vessels. The decrease of cerebral blood flow under anesthesia was observed in 8 out of 9 patients. The brain metabolism reaction varied showing a decrease in 6 patients and an increase in 3 patients.
Asunto(s)
Encéfalo/efectos de los fármacos , Circulación Cerebrovascular/efectos de los fármacos , Medicación Preanestésica , Adulto , Encéfalo/metabolismo , Diazepam , Fentanilo , Glucosa/metabolismo , Humanos , Aneurisma Intracraneal/fisiopatología , Aneurisma Intracraneal/cirugía , Lactatos/metabolismo , Ácido Láctico , Persona de Mediana Edad , Consumo de Oxígeno/efectos de los fármacos , SuccinilcolinaRESUMEN
OBJECTIVE: To study the brachiocephalic blood flow in patients after posterior fossa surgery in sitting position. MATERIAL AND METHODS: We examined 60 patients (44 women and 16 men, mean age from 46.45±13.2 years) after the surgery of neurinomas and meningiomas. The study of neurological symptoms and cerebral blood flow as well as computed tomography of the brain were performed. RESULTS AND CONCLUSION: No changes in the extracranial blood flow were found in patients without pneumocephalus or with a small amount of air in the intracranial cavity. Pneumocephalus decreased the linear velocity of the blood flow in the postoperative period. A trend towards the restoration of the blood flow along the inner carotid artery on both sides up to the preoperative level was found in patients with common pneumocephalus 24-48h after the surgery.