On the role of exploitation and exploration strategies in the maintenance of cognitive biases: Beyond the pursuit of instrumental rewards.

Why can initial biases persist in repeated choice tasks? Previous research has shown that frequent rewards can lure the decision maker into premature exploitation of a supposedly best option, which can result in the persistence of initial biases. Here, we demonstrate that even in the absence of rewards, initial biases can be perpetuated through a positive testing strategy. After eliciting a biased preference for one of two equally rewarding options, participants (N = 203) could sample freely from both options without the lure of any financial rewards. When participants were told to rule out alternatives in this phase, they explored the supposedly worse option and thereby managed to overcome their initial bias. When told to optimize their strategy, however, they exhibited a positive testing strategy resulting in the continued exploitation of the supposedly better option, a bias they maintained in an incentivized choice phase and later judgments. Across all participants, individual tendencies to exploit one option in earlier phases predicted biased behavior in subsequent phases. The findings highlight that not only the pursuit of instrumental rewards can lead to exploitation and the maintenance of initial biases. We discuss potential consequences for interventions.

Cognitive representations and the predictive brain depend heavily on the environment.

In their scholarly target article, Gilead et al. explain how abstract mental representations and the predictive brain enable prospection and time-traveling. However, their exclusive focus on intrapsychic capacities misses an important point, namely, the degree to which mind and brain are tuned by the environment. This neglected aspect of adaptive cognition is discussed and illustrated from a cognitive-ecological perspective.

The dynamics of choice in a changing world: Effects of full and partial feedback.

We explored the dynamics of choice behavior while the values of the options changed, unannounced, several times. In particular, choice dynamics were compared when the outcome values of all available options were known (full feedback) and when the outcome value of only the chosen option was known (partial feedback). The frequency of change, the values of the options, and the difference between them were also manipulated. In an experiment with N = 427, we found that the patterns of choices were different for the two levels of feedback. Whereas behavior in the full-feedback condition showed a tendency to switch choices following a missed opportunity-replicating previous findings-the behavior in the partial-feedback condition was different. It was sensitive to the outcome value of the chosen option in comparison to some memory of the last-experienced outcome value of the unchosen option. However, the comparison of these two values influenced choice behavior only when the outcome of the currently chosen option was satisfactory and the last outcome of the unchosen one was not. As expected, the other manipulated variables (change frequency, the options' values, and the difference between them) had no effect on the dynamics of behavior.

Higher order influences on evaluative priming: Processing styles moderate congruity effects.

A growing body of research challenges the automaticity of evaluative priming (EP). The present research adds to this literature by suggesting that EP is sensitive to processing styles. We relied on previous research showing that EP is determined by the extent to which the prime and the target events on a given trial are processed as a unified compound. Here, we further hypothesised that processing styles encouraging the inclusion of the prime to the target episode support congruity effects, whereas processing styles that enhance the exclusion of the prime from the target episode interrupt (or reverse) these effects. In Experiment 1, a preceding similarity search task produced a congruity effect, whereas a dissimilarity search task eliminated and (non-significantly) reversed this effect. In Experiments 2 and 3, we replicated and extended these findings using a global/local processing manipulation. Overall, these findings confirm that EP is flexible, open to top-down influences and strategic regulation.

Relational integrativity of prime-target pairs moderates congruity effects in evaluative priming.

In evaluative priming, positive or negative primes facilitate reactions to targets that share the same valence. While this effect is commonly explained as reflecting invariant structures in semantic long-term memory or in the sensorimotor system, the present research highlights the role of integrativity in evaluative priming. Integrativity refers to the ease of integrating two concepts into a new meaningful compound representation. In extended material tests using paired comparisons from two pools of positive and negative words, we show that evaluative congruity is highly correlated with integrativity. Therefore, in most priming studies, congruity and integrativity are strongly confounded. When both aspects are disentangled by manipulating congruity and integrativity orthogonally, three priming experiments show that evaluative-priming effects were confined to integrative prime-target pairs. No facilitation of prime-congruent targets was obtained for non-integrative stimuli. These findings are discussed from a broader perspective on priming conceived as flexible, context-dependent, and serving a generative adaptation function.

Anomalies in the detection of change: When changes in sample size are mistaken for changes in proportions.

Detecting changes, in performance, sales, markets, risks, social relations, or public opinions, constitutes an important adaptive function. In a sequential paradigm devised to investigate detection of change, every trial provides a sample of binary outcomes (e.g., correct vs. incorrect student responses). Participants have to decide whether the proportion of a focal feature (e.g., correct responses) in the population from which the sample is drawn has decreased, remained constant, or increased. Strong and persistent anomalies in change detection arise when changes in proportional quantities vary orthogonally to changes in absolute sample size. Proportional increases are readily detected and nonchanges are erroneously perceived as increases when absolute sample size increases. Conversely, decreasing sample size facilitates the correct detection of proportional decreases and the erroneous perception of nonchanges as decreases. These anomalies are however confined to experienced samples of elementary raw events from which proportions have to be inferred inductively. They disappear when sample proportions are described as percentages in a normalized probability format. To explain these challenging findings, it is essential to understand the inductive-learning constraints imposed on decisions from experience.

Functional research and cognitive-process research in behavioural science: An unequal but firmly connected pair.

Drawing on illustrative examples of the functional and cognitive psychology in contemporary research, the present article emphasizes the primacy of functional relationships, which provide the fundament for all attempts to uncover invisible cognitive processes. Cognitive research is not only inherently more difficult and much more ambitious than functional research. It also suffers from several home-made problems, such as unwarranted inferences from model fitting, the mediation-analysis cult and the failure to take environmental influences into account. However, despite the primacy of functional psychology and the problems associated with the ambitious goals of cognitive research, the two partners in this unequal pair are firmly connected and jointly responsible for the most impressive examples of progress in behavioural science.

Exploration of the neural correlates of ticklish laughter by functional magnetic resonance imaging.

The burst of laughter that is evoked by tickling is a primitive form of vocalization. It evolves during an early phase of postnatal life and appears to be independent of higher cortical circuits. Clinicopathological observations have led to suspicions that the hypothalamus is directly involved in the production of laughter. In this functional magnetic resonance imaging investigation, healthy participants were 1) tickled on the sole of the right foot with permission to laugh, 2) tickled but asked to stifle laughter, and 3) requested to laugh voluntarily. Tickling that was accompanied by involuntary laughter activated regions in the lateral hypothalamus, parietal operculum, amygdala, and right cerebellum to a consistently greater degree than did the 2 other conditions. Activation of the periaqueductal gray matter was observed during voluntary and involuntary laughter but not when laughter was inhibited. The present findings indicate that hypothalamic activity plays a crucial role in evoking ticklish laughter in healthy individuals. The hypothalamus promotes innate behavioral reactions to stimuli and sends projections to the periaqueductal gray matter, which is itself an important integrative center for the control of vocalization. A comparison of our findings with published data relating to humorous laughter revealed the involvement of a common set of subcortical centers.

Research practices that can prevent an inflation of false-positive rates.

Recent studies have indicated that research practices in psychology may be susceptible to factors that increase false-positive rates, raising concerns about the possible prevalence of false-positive findings. The present article discusses several practices that may run counter to the inflation of false-positive rates. Taking these practices into account would lead to a more balanced view on the false-positive issue. Specifically, we argue that an inflation of false-positive rates would diminish, sometimes to a substantial degree, when researchers (a) have explicit a priori theoretical hypotheses, (b) include multiple replication studies in a single paper, and (c) collect additional data based on observed results. We report findings from simulation studies and statistical evidence that support these arguments. Being aware of these preventive factors allows researchers not to overestimate the pervasiveness of false-positives in psychology and to gauge the susceptibility of a paper to possible false-positives in practical and fair ways.

Using theoretical constraints and the TASI taxonomy to delineate predictably replicable findings.

The focus of the present article is not on failures to replicate but on the more optimistically framed and more fruitful question: What stable findings can be reproduced reliably and can be trusted by decision makers, managers, health agents, or politicians? We propagate the working hypothesis that a twofold key to stable and replicable findings lies in the existence of theoretical constraints and, no less important, in researchers' sensitivity to metatheoretical, auxiliary assumptions. We introduce a hierarchy of four levels of theoretical constraints-a priori principles, psychophysical, empirical, and modelling constraints-combined with the TASI taxonomy of theoretical, auxiliary, statistical, and inferential assumptions Trafimow, Journal for the Theory of Social Behaviour, 52, 37-48, (2022). Although theoretical constraints clearly facilitate stable and replicable research findings, TASI reminds us of various reasons why even perfectly valid hypotheses need not always be borne out. The presented framework should help researchers to operationalize conditions under which theoretical constraints render empirical findings most predictable.

An exploration of physics envy with implications for desiderata of psychology theories.

There is a trepidation, anxiety, or intuition, which has persisted for more than a century, that psychology theories are less anchored in fundamental laws than physics theories. Rather than attempt to refute the concern, the present work accepts it and tries out candidate explanations. These pertain to empirical laws, parsimony, scope, reductionism, falsifiability, mathematical operations (multiplication vs. addition), internal coherence, ceteris paribus stipulations, and purposeful omission of relevant factors (idealization). The conceptions underlying these explanations are not strictly independent, but they point to different distinctive features that might account for the unequal status of physics and psychological science and to different means of improving contemporary psychology. Although the available evidence for or against these candidate explanations is scarce and relies mainly on a few telling examples, we conclude that the last of our candidate explanations-reliance on idealized universes-works best and leads to the most insights about what psychology might learn from physics and what research strategies might foster the ideal of theory-driven psychological science in the future. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Small Sample Size and Group Homogeneity: A Crucial Ingredient to Inter-Group Bias.

Applying a recently developed framework for the study of sample-based person impressions to the level of group impressions resulted in convergent evidence for a highly robust judgment process. How stimulus traits mapped on the resulting group impressions was subject to two distinct moderators, diagnosticity of traits, and the amplifying impact of early sample truncation. Three indices of diagnosticity-negative valence, extremity, and distance to other traits in a density framework-determined participants' decision to truncate trait sampling early and hence the final group judgments. When trait samples were negative and extreme and when the distance between high-density traits was small, early truncation of the trait samples fostered high group homogeneity and polarized impressions. Granting that mental representations of in-groups and out-groups rely on systematically different samples, our sampling approach can account for various inter-group biases: out-group homogeneity, out-group polarization and (because negative traits are more diagnostic) out-group derogation.

Dynamics of Endothelial Cell Diversity and Plasticity in Health and Disease.

Endothelial cells (ECs) are vital structural units of the cardiovascular system possessing two principal distinctive properties: heterogeneity and plasticity. Endothelial heterogeneity is defined by differences in tissue-specific endothelial phenotypes and their high predisposition to modification along the length of the vascular bed. This aspect of heterogeneity is closely associated with plasticity, the ability of ECs to adapt to environmental cues through the mobilization of genetic, molecular, and structural alterations. The specific endothelial cytoarchitectonics facilitate a quick structural cell reorganization and, furthermore, easy adaptation to the extrinsic and intrinsic environmental stimuli, known as the epigenetic landscape. ECs, as universally distributed and ubiquitous cells of the human body, play a role that extends far beyond their structural function in the cardiovascular system. They play a crucial role in terms of barrier function, cell-to-cell communication, and a myriad of physiological and pathologic processes. These include development, ontogenesis, disease initiation, and progression, as well as growth, regeneration, and repair. Despite substantial progress in the understanding of endothelial cell biology, the role of ECs in healthy conditions and pathologies remains a fascinating area of exploration. This review aims to summarize knowledge and concepts in endothelial biology. It focuses on the development and functional characteristics of endothelial cells in health and pathological conditions, with a particular emphasis on endothelial phenotypic and functional heterogeneity.

Pseudocontingencies derived from categorically organized memory representations.

Pseudocontingencies (PCs) allow for inferences about the contingency between two variables X and Y when the conditions for genuine contingency assessment are not met. Even when joint observations X i and Y i about the same reference objects i are not available or are detached in time or space, the correlation r(X i ,Y i ) is readily inferred from base rates. Inferred correlations are positive (negative) if X and Y base rates are skewed in the same (different) directions. Such PC inferences afford useful proxies for actually existing contingencies. While previous studies have focused on PCs due to environmental base rates, the present research highlights memory organization as a natural source of PC effects. When information about two attributes X and Y is represented in a hierarchically organized categorical memory code, as category-wise base rates p(X) and p(Y), the reconstruction of item-level information from category base rates will naturally produce PC effects. Three experiments support this contention. When the yes base rates of two respondents in four questionnaire subscales (categories) were correlated, recalled and predicted item-level responses were correlated in the same direction, even when the original responses to specific items within categories were correlated in the opposite direction.

Pragmatic, constructive, and reconstructive memory influences on the hindsight bias.

In hindsight, when the outcome of an uncertain scenario is already known, we typically feel that this outcome was always likely; hindsight judgments of outcome probabilities exceed foresight judgments of the same probabilities without outcome knowledge. We extend prior accounts of hindsight bias with the influence of pragmatic communication inherent in the task and the consolidation of self-generated responses across time. In a novel 3 × 2 within-participants design, with three sequential judgments of outcome probabilities in two scenarios, we replicated the within-participants hindsight bias observed in the classic memory design and the between-participants hindsight bias in a hypothetical design simultaneously. Moreover, we reversed the classic memory design and showed that subjective probabilities also decreased when participants encountered foresight instructions after hindsight instructions, demonstrating that previously induced outcome knowledge did not prevent unbiased judgments. The constructive impact of self-generated and communicated judgments ("saying is believing") was apparent after a 2-week consolidation period: Not outcome knowledge, but rather the last pragmatic response (either biased or unbiased) determined judgments at the third measurement. These findings highlight the short-term malleability of hindsight influences in response to task pragmatics and has major implications for debiasing.

Predicting and preventing ovarian hyperstimulation syndrome (OHSS): the need for individualized not standardized treatment.

Ovarian hyperstimulation syndrome (OHSS) is the most serious complication of controlled ovarian stimulation (COS) as part of assisted reproductive technologies (ART). While the safety and efficacy of ART is well established, physicians should always be aware of the risk of OHSS in patients undergoing COS, as it can be fatal. This article will briefly present the pathophysiology of OHSS, including the key role of vascular endothelial growth factor (VEGF), to provide the foundation for an overview of current techniques for the prevention of OHSS. Risk factors and predictive factors for OHSS will be presented, as recognizing these risk factors and individualizing the COS protocol appropriately is the key to the primary prevention of OHSS, as the benefits and risks of each COS strategy vary among individuals. Individualized COS (iCOS) could effectively eradicate OHSS, and the identification of hormonal, functional and genetic markers of ovarian response will facilitate iCOS. However, if iCOS is not properly applied, various preventive measures can be instituted once COS has begun, including cancelling the cycle, coasting, individualizing the human chorionic gonadotropin trigger dose or using a gonadotropin-releasing hormone (GnRH) agonist (for those using a GnRH antagonist protocol), the use of intravenous fluids at the time of oocyte retrieval, and cryopreserving/vitrifying all embryos for subsequent transfer in an unstimulated cycle. Some of these techniques have been widely adopted, despite the scarcity of data from randomized clinical trials to support their use.

The impact of open and closed mindsets on evaluative priming.

In the present research, we argue that open versus closed mindsets, accompanying ongoing versus completed mental jobs on the prime, determine the size of congruity effects in the evaluative priming paradigm. More specifically, we hypothesised that disfluent primes that resist an easily completed encoding process should induce an open mindset and thereby result in stronger congruity effects than fluent primes that induce closed mindsets. Across two experiments, we applied two different manipulations of prime fluency: gradual demasking (experiment 1) and colour contrast (experiment 2). As expected, in both experiments we found robust congruity effects, but only on trials with disfluent (vs. fluent) primes. Results of a follow-up experiment suggest that these effects are not due to attentional processes. We conclude that the mindsets resulting from individuals' activities during encoding are crucial in determining the outcome of evaluative priming effects.

On the adaptive flexibility of evaluative priming.

If priming effects serve an adaptive function, they have to be both robust and flexible. In four experiments, we demonstrated regular evaluative-priming effects for relatively long stimulus-onset asynchronies, which can, however, be eliminated or reversed strategically. When participants responded to both primes and targets, rather than only to targets, the standard congruity effect disappeared. In Experiments 1a-1c, this result was regularly obtained, independently of the prime response (valence or gender classification) and the response mode (pronunciation or keystroke). In Experiment 2, we showed that once the default congruity effect was eliminated, strategic-priming effects reflected the statistical contingency between prime valence and target valence. Positive contingencies produced congruity, whereas negative contingencies produced equally strong incongruity effects. Altogether, these findings are consistent with an adaptive-cognitive perspective, which highlights the role of flexible strategic processes in working memory as opposed to fixed structures in semantic long-term memory or in the sensorimotor system.

Evaluative conditioning depends on higher order encoding processes.

Evaluative conditioning (EC) is commonly conceived as stimulus-driven associative learning. Here, we show that internally generated encoding activities mediate EC effects: Neutral conditioned stimuli (CS) faces were paired with positive and negative unconditioned stimuli (US) faces. Depending on the encoding task (Is CS a friend vs. enemy of US?), Experiment 1 yielded either normal EC effects (CS adopting US valence) or a reversal. This pattern was conditional on the degree to which encoding judgements affirmed friend or enemy encoding schemes. Experiments 2a and 2b replicated these findings with more clearly valenced US faces and controlling for demand effects. Experiment 3 demonstrated unconditional encoding effects when participants generated friend or enemy relations between CS and US faces. Explicitly stated friend or enemy relations in Experiment 4 left EC effects unaffected. Together, these findings testify to the importance of higher order cognitive processes in conditioning, much in line with recent evidence on the crucial role of conditioning awareness.

An adaptive-learning approach to affect regulation: strategic influences on evaluative priming.

An adaptive cognition approach to evaluative priming is not compatible with the view that the entire process is automatically determined by prime stimulus valence alone. In addition to the evaluative congruity of individual prime-target pairs, an adaptive regulation function should be sensitive to the base rates of positive and negative stimuli as well as to the perceived contingency between prime and target valence. The present study was particularly concerned with pseudocontingent inferences that offer a proxy for the assessment of contingencies from degraded or incomplete stimulus input. As expected, response latencies were shorter for the more prevalent target valence and for evaluatively congruent trials. However, crucially, the congruity effect was eliminated and overridden by pseudocontingencies inferred from the stimulus environment. These strategic inferences were further enhanced when the task called for the evaluation of both prime stimuli and target stimuli.