Detalles de la búsqueda
1.
Molecular Design in Practice: A Review of Selected Projects in a French Research Institute That Illustrates the Link between Chemical Biology and Medicinal Chemistry.
Molecules
; 26(19)2021 Oct 08.
Artículo
Inglés
| MEDLINE | ID: mdl-34641626
2.
Unconventional surface plasmon resonance signals reveal quantitative inhibition of transcriptional repressor EthR by synthetic ligands.
Anal Biochem
; 452: 54-66, 2014 May 01.
Artículo
Inglés
| MEDLINE | ID: mdl-24561027
3.
Pyridylpiperazine efflux pump inhibitor boosts in vivo antibiotic efficacy against K. pneumoniae.
EMBO Mol Med
; 16(1): 93-111, 2024 Jan.
Artículo
Inglés
| MEDLINE | ID: mdl-38177534
4.
On the mechanism of degradation of oxytocin and its analogues in aqueous solution.
Biopolymers
; 100(4): 408-21, 2013 Jul.
Artículo
Inglés
| MEDLINE | ID: mdl-23868209
5.
Antibiotics with novel mode of action as new weapons to fight antimicrobial resistance.
Eur J Med Chem
; 256: 115413, 2023 Aug 05.
Artículo
Inglés
| MEDLINE | ID: mdl-37150058
6.
Update on the Discovery of Efflux Pump Inhibitors against Critical Priority Gram-Negative Bacteria.
Antibiotics (Basel)
; 12(1)2023 Jan 15.
Artículo
Inglés
| MEDLINE | ID: mdl-36671381
7.
Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers' Lactamization.
Pharmaceuticals (Basel)
; 16(3)2023 Mar 08.
Artículo
Inglés
| MEDLINE | ID: mdl-36986512
8.
Characterization of pyridylpiperazine-based efflux pump inhibitors for Acinetobacter baumannii.
JAC Antimicrob Resist
; 5(5): dlad112, 2023 Oct.
Artículo
Inglés
| MEDLINE | ID: mdl-37881353
9.
Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump.
Eur J Med Chem
; 259: 115630, 2023 Nov 05.
Artículo
Inglés
| MEDLINE | ID: mdl-37459793
10.
Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification.
Pharmaceuticals (Basel)
; 16(3)2023 Feb 22.
Artículo
Inglés
| MEDLINE | ID: mdl-36986435
11.
On the Hunt for Next-Generation Antimicrobial Agents: An Online Symposium Organized Jointly by the French Society for Medicinal Chemistry (Société de Chimie Thérapeutique) and the French Microbiology Society (Société Française de Microbiologie) on 9-10 December 2021.
Pharmaceuticals (Basel)
; 15(4)2022 Mar 23.
Artículo
Inglés
| MEDLINE | ID: mdl-35455385
12.
Tricyclic SpiroLactams Kill Mycobacteria In Vitro and In Vivo by Inhibiting Type II NADH Dehydrogenases.
J Med Chem
; 65(24): 16651-16664, 2022 12 22.
Artículo
Inglés
| MEDLINE | ID: mdl-36473699
13.
Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps.
Nat Commun
; 13(1): 115, 2022 01 10.
Artículo
Inglés
| MEDLINE | ID: mdl-35013254
14.
The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis.
Sci Transl Med
; 14(643): eaaz6280, 2022 05 04.
Artículo
Inglés
| MEDLINE | ID: mdl-35507672
15.
Fragment-Based Optimized EthR Inhibitors with in Vivo Ethionamide Boosting Activity.
ACS Infect Dis
; 6(3): 366-378, 2020 03 13.
Artículo
Inglés
| MEDLINE | ID: mdl-32011115
16.
Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening.
Eur J Med Chem
; 200: 112440, 2020 Aug 15.
Artículo
Inglés
| MEDLINE | ID: mdl-32505086
17.
A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.
Biochim Biophys Acta Proteins Proteom
; 1867(3): 248-258, 2019 03.
Artículo
Inglés
| MEDLINE | ID: mdl-30553830
18.
A fragment-based approach towards the discovery of N-substituted tropinones as inhibitors of Mycobacterium tuberculosis transcriptional regulator EthR2.
Eur J Med Chem
; 167: 426-438, 2019 Apr 01.
Artículo
Inglés
| MEDLINE | ID: mdl-30784877
19.
Intrinsic Antibacterial Activity of Nanoparticles Made of ß-Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis.
ACS Nano
; 13(4): 3992-4007, 2019 04 23.
Artículo
Inglés
| MEDLINE | ID: mdl-30822386
20.
Structural rearrangements occurring upon cofactor binding in the Mycobacterium smegmatis ß-ketoacyl-acyl carrier protein reductase MabA.
Acta Crystallogr D Struct Biol
; 74(Pt 5): 383-393, 2018 05 01.
Artículo
Inglés
| MEDLINE | ID: mdl-29717709