[Hematuria in children: retrospective study of 128 pediatric patients] / Hematúria na criança: estudo retrospectivo de 128 casos.

OBJECTIVE: To evaluate the diagnostic frequency of the various diseases associated with the development of hematuria in children, in a pediatric nephrology unit pertaining to a university hospital. METHODS: The clinical records of 128 children (70 male, 50 female) who presented intermittent/persistent macroscopic hematuria or persistent microscopic hematuria as the chief clinical complaint/finding, in the period of 1978-1995, were retrospectively analyzed. This evaluation was performed with special attention to the patientacute;s clinical history, physical examination, personal and family morbid history information. Patients whose investigation was not complete were not considered for analysis. The mean age on presentation was 8.2 years (5 months - 16 years) and the mean period of observation was 3.2 years (1 month-15 years). RESULTS: Macroscopic hematuria occurred in 104 patients and persistent microscopic hematuria was present in 24 patients. Urinary metabolic disturbances and urinary lithiasis, alone or in association, were diagnosed in the majority of the patients (65.5%). Hypercalciuria was the urinary metabolic disturbance (90.1%) mostly detected, either alone (73.2%) or in association with hyperuricosuria (16.9%). A positive family history of lithiasis was reported in 32.1% of the patients in which the diagnosis of lithiasis/urinary metabolic disturbance was confirmed. Glomerulopathies were diagnosed in 25% of the patients, with the predominance of post-infectious acute glomerulonephritis (11 patients, 34%). In 6 children, the etiology of hematuria was not elucidated, despite extensive investigation, including renal biopsy.CONCLUSION: The authors present an algorithm for the diagnosis of hematuria in children and suggest that in cases of isolated hematuria, presenting without clinical clues to the possible etiology, laboratory investigation should be started with the evaluation of urinary metabolic disturbances / lithiasis.

Sindrome nefrotica na lues secundaria.Apresentacao de um caso e revisao da literatura. / Nephrotic syndrome in secondary lues. Presentation of a case and review of the literature

Os autores apresentam um caso de sindrome nefrotica consequente a lues secundaria, em crianca de sexo feminino com seis anos de idade. Sao comentados os dados obtidos atraves da biopsia renal (microscopia optica e imunofluorescencia) e os aspectos clinicos sao revistos a luz da bibliografia

Osteodistrofia renal: achados radiologicos. / Renal osteodystrophy: radiologic findinds

Os autores apresentam um paciente com insuficiencia renal cronica e com sinais radiologicos de osteodistrofia renal avancada, caracterizada predominantemente por sinais de hiperparatiroidismo secundario, osteoesclerose, requitismo e atrazo do desenvolvimento osseo.Apos 3 meses de tratamento com calcitriol, observou-se melhora radiologica da reabsorcao ossea