Búsqueda | Biblioteca Virtual en Salud

1.

Sex-specific modulation of amyloid-ß on tau phosphorylation underlies faster tangle accumulation in females.

Wang, Yi-Ting; Therriault, Joseph; Servaes, Stijn; Tissot, Cécile; Rahmouni, Nesrine; Macedo, Arthur Cassa; Fernandez-Arias, Jaime; Mathotaarachchi, Sulantha S; Benedet, Andréa L; Stevenson, Jenna; Ashton, Nicholas J; Lussier, Firoza Z; Pascoal, Tharick A; Zetterberg, Henrik; Rajah, Maria Natasha; Blennow, Kaj; Gauthier, Serge; Rosa-Neto, Pedro.

Brain ; 147(4): 1497-1510, 2024 Apr 04.

Artículo Inglés | MEDLINE | ID: mdl-37988283

2.

Focusing on Earlier Management of Alzheimer Disease: Expert Opinion Based on a Modified Nominal Group Technique.

Frederiksen, Kristian Steen; Morató, Xavier; Zetterberg, Henrik; Gauthier, Serge; Boada, Mercè; Pytel, Vanesa; Mattke, Soeren.

Alzheimer Dis Assoc Disord ; 38(1): 1-7, 2024.

Artículo Inglés | MEDLINE | ID: mdl-38300883

3.

Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-ß positive individuals.

Woo, Marcel S; Tissot, Cécile; Lantero-Rodriguez, Juan; Snellman, Anniina; Therriault, Joseph; Rahmouni, Nesrine; Macedo, Arthur C; Servaes, Stijn; Wang, Yi-Ting; Arias, Jaime Fernandez; Hosseini, Seyyed Ali; Chamoun, Mira; Lussier, Firoza Z; Benedet, Andrea L; Ashton, Nicholas J; Karikari, Thomas K; Triana-Baltzer, Gallen; Kolb, Hartmuth C; Stevenson, Jenna; Mayer, Christina; Kobayashi, Eliane; Massarweh, Gassan; Friese, Manuel A; Pascoal, Tharick A; Gauthier, Serge; Zetterberg, Henrik; Blennow, Kaj; Rosa-Neto, Pedro.

Alzheimers Dement ; 20(2): 1166-1174, 2024 Feb.

Artículo Inglés | MEDLINE | ID: mdl-37920945

4.

Advanced brain imaging for the diagnosis of Alzheimer disease.

Wang, Yi-Ting Tina; Rosa-Neto, Pedro; Gauthier, Serge.

Curr Opin Neurol ; 36(5): 481-490, 2023 10 01.

Artículo Inglés | MEDLINE | ID: mdl-37639461

5.

14-3-3 [Formula: see text]-reported early synaptic injury in Alzheimer's disease is independently mediated by sTREM2.

Woo, Marcel S; Nilsson, Johanna; Therriault, Joseph; Rahmouni, Nesrine; Brinkmalm, Ann; Benedet, Andrea L; Ashton, Nicholas J; Macedo, Arthur C; Servaes, Stijn; Wang, Yi-Ting; Tissot, Cécile; Arias, Jaime Fernandez; Hosseini, Seyyed Ali; Chamoun, Mira; Lussier, Firoza Z; Karikari, Thomas K; Stevenson, Jenna; Mayer, Christina; Ferrari-Souza, João Pedro; Kobayashi, Eliane; Massarweh, Gassan; Friese, Manuel A; Pascoal, Tharick A; Gauthier, Serge; Zetterberg, Henrik; Blennow, Kaj; Rosa-Neto, Pedro.

J Neuroinflammation ; 20(1): 278, 2023 Nov 24.

Artículo Inglés | MEDLINE | ID: mdl-38001539

6.

Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease.

Joseph-Mathurin, Nelly; Llibre-Guerra, Jorge J; Li, Yan; McCullough, Austin A; Hofmann, Carsten; Wojtowicz, Jakub; Park, Ethan; Wang, Guoqiao; Preboske, Gregory M; Wang, Qing; Gordon, Brian A; Chen, Charles D; Flores, Shaney; Aggarwal, Neelum T; Berman, Sarah B; Bird, Thomas D; Black, Sandra E; Borowski, Bret; Brooks, William S; Chhatwal, Jasmeer P; Clarnette, Roger; Cruchaga, Carlos; Fagan, Anne M; Farlow, Martin; Fox, Nick C; Gauthier, Serge; Hassenstab, Jason; Hobbs, Diana A; Holdridge, Karen C; Honig, Lawrence S; Hornbeck, Russ C; Hsiung, Ging-Yuek R; Jack, Clifford R; Jimenez-Velazquez, Ivonne Z; Jucker, Mathias; Klein, Gregory; Levin, Johannes; Mancini, Michele; Masellis, Mario; McKay, Nicole S; Mummery, Catherine J; Ringman, John M; Shimada, Hiroyuki; Snider, B Joy; Suzuki, Kazushi; Wallon, David; Xiong, Chengjie; Yaari, Roy; McDade, Eric; Perrin, Richard J.

Ann Neurol ; 92(5): 729-744, 2022 11.

Artículo Inglés | MEDLINE | ID: mdl-36151869

7.

Longitudinal head-to-head comparison of ¹¹C-PiB and ¹⁸F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-ß monoclonal antibodies in dominantly inherited Alzheimer's disease.

Chen, Charles D; McCullough, Austin; Gordon, Brian; Joseph-Mathurin, Nelly; Flores, Shaney; McKay, Nicole S; Hobbs, Diana A; Hornbeck, Russ; Fagan, Anne M; Cruchaga, Carlos; Goate, Alison M; Perrin, Richard J; Wang, Guoqiao; Li, Yan; Shi, Xinyu; Xiong, Chengjie; Pontecorvo, Michael J; Klein, Gregory; Su, Yi; Klunk, William E; Jack, Clifford; Koeppe, Robert; Snider, B Joy; Berman, Sarah B; Roberson, Erik D; Brosch, Jared; Surti, Ghulam; Jiménez-Velázquez, Ivonne Z; Galasko, Douglas; Honig, Lawrence S; Brooks, William S; Clarnette, Roger; Wallon, David; Dubois, Bruno; Pariente, Jérémie; Pasquier, Florence; Sanchez-Valle, Raquel; Shcherbinin, Sergey; Higgins, Ixavier; Tunali, Ilke; Masters, Colin L; van Dyck, Christopher H; Masellis, Mario; Hsiung, Robin; Gauthier, Serge; Salloway, Steve; Clifford, David B; Mills, Susan; Supnet-Bell, Charlene; McDade, Eric.

Eur J Nucl Med Mol Imaging ; 50(9): 2669-2682, 2023 07.

Artículo Inglés | MEDLINE | ID: mdl-37017737

8.

Astrocyte biomarker signatures of amyloid-ß and tau pathologies in Alzheimer's disease.

Ferrari-Souza, João Pedro; Ferreira, Pâmela C L; Bellaver, Bruna; Tissot, Cécile; Wang, Yi-Ting; Leffa, Douglas T; Brum, Wagner S; Benedet, Andréa L; Ashton, Nicholas J; De Bastiani, Marco Antônio; Rocha, Andréia; Therriault, Joseph; Lussier, Firoza Z; Chamoun, Mira; Servaes, Stijn; Bezgin, Gleb; Kang, Min Su; Stevenson, Jenna; Rahmouni, Nesrine; Pallen, Vanessa; Poltronetti, Nina Margherita; Klunk, William E; Tudorascu, Dana L; Cohen, Ann D; Villemagne, Victor L; Gauthier, Serge; Blennow, Kaj; Zetterberg, Henrik; Souza, Diogo O; Karikari, Thomas K; Zimmer, Eduardo R; Rosa-Neto, Pedro; Pascoal, Tharick A.

Mol Psychiatry ; 27(11): 4781-4789, 2022 Nov.

Artículo Inglés | MEDLINE | ID: mdl-35948658

9.

18F-MK-6240 tau-PET in genetic frontotemporal dementia.

Levy, Jake P; Bezgin, Gleb; Savard, Melissa; Pascoal, Tharick A; Finger, Elizabeth; Laforce, Robert; Sonnen, Joshua A; Soucy, Jean-Paul; Gauthier, Serge; Rosa-Neto, Pedro; Ducharme, Simon.

Brain ; 145(5): 1763-1772, 2022 06 03.

Artículo Inglés | MEDLINE | ID: mdl-34664612

10.

Health System Change for Alzheimer's Disease-Modifying Therapies in Canada: Beginning the Discussion.

Frank, Andrew; Ismail, Zahinoor; Wilson, Melanie; Gauthier, Serge; Verret, Louis; Hsiung, Ging-Yuek Robin; Borrie, Michael.

Can J Neurol Sci ; : 1-9, 2023 Dec 06.

Artículo Inglés | MEDLINE | ID: mdl-38052729

11.

Feasibility of a standard cognitive assessment in European academic memory clinics.

Grazia, Alice; Altomare, Daniele; Preis, Lukas; Monsch, Andreas U; Cappa, Stefano F; Gauthier, Serge; Frölich, Lutz; Winblad, Bengt; Welsh-Bohmer, Kathleen A; Teipel, Stefan J; Boccardi, Marina.

Alzheimers Dement ; 19(6): 2276-2286, 2023 06.

Artículo Inglés | MEDLINE | ID: mdl-36453876

12.

Equivalence of plasma p-tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease.

Therriault, Joseph; Servaes, Stijn; Tissot, Cécile; Rahmouni, Nesrine; Ashton, Nicholas J; Benedet, Andréa Lessa; Karikari, Thomas K; Macedo, Arthur C; Lussier, Firoza Z; Stevenson, Jenna; Wang, Yi-Ting; Fernandez-Arias, Jaime; Stevenson, Alyssa; Socualaya, Kely Quispialaya; Haeger, Arlette; Nazneen, Tahnia; Aumont, Étienne; Hosseini, Ali; Rej, Soham; Vitali, Paolo; Triana-Baltzer, Gallen; Kolb, Hartmuth C; Soucy, Jean-Paul; Pascoal, Tharick A; Gauthier, Serge; Zetterberg, Henrik; Blennow, Kaj; Rosa-Neto, Pedro.

Alzheimers Dement ; 19(11): 4967-4977, 2023 Nov.

Artículo Inglés | MEDLINE | ID: mdl-37078495

13.

Blood-brain barrier integrity impacts the use of plasma amyloid-ß as a proxy of brain amyloid-ß pathology.

Bellaver, Bruna; Puig-Pijoan, Albert; Ferrari-Souza, João Pedro; Leffa, Douglas T; Lussier, Firoza Z; Ferreira, Pamela C L; Tissot, Cécile; Povala, Guilherme; Therriault, Joseph; Benedet, Andréa L; Ashton, Nicholas J; Servaes, Stijn; Chamoun, Mira; Stevenson, Jenna; Rahmouni, Nesrine; Vermeiren, Marie; Macedo, Arthur C; Fernández-Lebrero, Aida; García-Escobar, Greta; Navalpotro-Gómez, Irene; Lopez, Oscar; Tudorascu, Dana L; Cohen, Ann; Villemagne, Victor L; Klunk, William E; Gauthier, Serge; Zimmer, Eduardo R; Karikari, Thomas K; Blennow, Kaj; Zetterberg, Henrik; Suárez-Calvet, Marc; Rosa-Neto, Pedro; Pascoal, Tharick A.

Alzheimers Dement ; 19(9): 3815-3825, 2023 09.

Artículo Inglés | MEDLINE | ID: mdl-36919582

14.

Plasma p-tau231 and p-tau217 inform on tau tangles aggregation in cognitively impaired individuals.

Ferreira, Pamela C L; Therriault, Joseph; Tissot, Cécile; Ferrari-Souza, João Pedro; Benedet, Andréa L; Povala, Guilherme; Bellaver, Bruna; Leffa, Douglas T; Brum, Wagner S; Lussier, Firoza Z; Bezgin, Gleb; Servaes, Stijn; Vermeiren, Marie; Macedo, Arthur C; Cabrera, Arlec; Stevenson, Jenna; Triana-Baltzer, Gallen; Kolb, Hartmuth; Rahmouni, Nesrine; Klunk, William E; Lopez, Oscar L; Villemagne, Victor L; Cohen, Ann; Tudorascu, Dana L; Zimmer, Eduardo R; Karikari, Thomas K; Ashton, Nicholas J; Zetterberg, Henrik; Blennow, Kaj; Gauthier, Serge; Rosa-Neto, Pedro; Pascoal, Tharick A.

Alzheimers Dement ; 19(10): 4463-4474, 2023 10.

Artículo Inglés | MEDLINE | ID: mdl-37534889

15.

Amyloid processing in COVID-19-associated neurological syndromes.

Ziff, Oliver J; Ashton, Nicholas J; Mehta, Puja R; Brown, Rachel; Athauda, Dilan; Heaney, Judith; Heslegrave, Amanda J; Benedet, Andrea Lessa; Blennow, Kaj; Checkley, Anna M; Houlihan, Catherine F; Gauthier, Serge; Rosa-Neto, Pedro; Fox, Nick C; Schott, Jonathan M; Zetterberg, Henrik; Benjamin, Laura A; Paterson, Ross W.

J Neurochem ; 161(2): 146-157, 2022 04.

Artículo Inglés | MEDLINE | ID: mdl-35137414

16.

APOEÎµ4 potentiates the relationship between amyloid-ß and tau pathologies.

Therriault, Joseph; Benedet, Andrea L; Pascoal, Tharick A; Mathotaarachchi, Sulantha; Savard, Melissa; Chamoun, Mira; Thomas, Emilie; Kang, Min Su; Lussier, Firoza; Tissot, Cecile; Soucy, Jean-Paul; Massarweh, Gassan; Rej, Soham; Saha-Chaudhuri, Paramita; Poirier, Judes; Gauthier, Serge; Rosa-Neto, Pedro.

Mol Psychiatry ; 26(10): 5977-5988, 2021 10.

Artículo Inglés | MEDLINE | ID: mdl-32161362

17.

Amyloid-beta modulates the association between neurofilament light chain and brain atrophy in Alzheimer's disease.

Kang, Min Su; Aliaga, Arturo Aliaga; Shin, Monica; Mathotaarachchi, Sulantha; Benedet, Andrea L; Pascoal, Tharick A; Therriault, Joseph; Chamoun, Mira; Savard, Melissa; Devenyi, Gabriel A; Mathieu, Axel; Chakravarty, M Mallar; Sandelius, Åsa; Blennow, Kaj; Zetterberg, Henrik; Soucy, Jean-Paul; Cuello, A Claudio; Massarweh, Gassan; Gauthier, Serge; Rosa-Neto, Pedro.

Mol Psychiatry ; 26(10): 5989-6001, 2021 10.

Artículo Inglés | MEDLINE | ID: mdl-32591633

18.

Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid.

Gobom, Johan; Parnetti, Lucilla; Rosa-Neto, Pedro; Vyhnalek, Martin; Gauthier, Serge; Cataldi, Samuela; Lerch, Ondrej; Laczo, Jan; Cechova, Katerina; Clarin, Marcus; Benet, Andrea L; Pascoal, Tharick A; Rahmouni, Neserine; Vandijck, Manu; Huyck, Else; Le Bastard, Nathalie; Stevenson, Jenna; Chamoun, Mira; Alcolea, Daniel; Lleó, Alberto; Andreasson, Ulf; Verbeek, Marcel M; Bellomo, Giovanni; Rinaldi, Roberta; Ashton, Nicholas J; Zetterberg, Henrik; Sheardova, Katerina; Hort, Jakub; Blennow, Kaj.

Clin Chem Lab Med ; 60(2): 207-219, 2022 01 27.

Artículo Inglés | MEDLINE | ID: mdl-34773730

19.

Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages.

Pascoal, Tharick A; Benedet, Andrea L; Tudorascu, Dana L; Therriault, Joseph; Mathotaarachchi, Sulantha; Savard, Melissa; Lussier, Firoza Z; Tissot, Cécile; Chamoun, Mira; Kang, Min Su; Stevenson, Jenna; Massarweh, Gassan; Guiot, Marie-Christine; Soucy, Jean-Paul; Gauthier, Serge; Rosa-Neto, Pedro.

Brain ; 144(11): 3517-3528, 2021 12 16.

Artículo Inglés | MEDLINE | ID: mdl-34515754

20.

Plasma p-tau231: a new biomarker for incipient Alzheimer's disease pathology.

Ashton, Nicholas J; Pascoal, Tharick A; Karikari, Thomas K; Benedet, Andréa L; Lantero-Rodriguez, Juan; Brinkmalm, Gunnar; Snellman, Anniina; Schöll, Michael; Troakes, Claire; Hye, Abdul; Gauthier, Serge; Vanmechelen, Eugeen; Zetterberg, Henrik; Rosa-Neto, Pedro; Blennow, Kaj.

Acta Neuropathol ; 141(5): 709-724, 2021 05.

Artículo Inglés | MEDLINE | ID: mdl-33585983

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