A Current Review in the Orthopedic Management of Osteonecrosis of the knee Secondary to Treatment of Pediatric Hematologic Malignancy.

Acute Lymphoblastic Leukemia is the most prevalent pediatric hematologic malignancy. The treatment for this illness has advanced significantly, now touting a 90% cure rate. Although these patients often become disease free, treatment can leave devastating effects that last long after their disease burden is alleviated. A commonly experienced result of treatment is osteonecrosis (ON), often occurring in weight bearing joints. Uncertainty exists in the optimal treatment of this cohort of patients. In this review, we describe the etiology and suspected pathogenesis of ON, as well as treatment options described in the literature.

Intralaminar Screw Fixation of Spondylolysis.

Spondylolysis, defined as injury to the pars interarticularis, is the most common identifiable cause of back pain in children. Historically, treatment has primarily been nonoperative, including physical therapy, activity modification, and occasionally bracing1. In instances in which the condition is refractory to nonoperative management, however, surgical treatment may be an efficacious alternative. Persistent pain following nonoperative management is described as occurring in 6% of the general population, but is reported to be as high as 15% to 47% in the pediatric population who participate in sports2,3. There have been several proposed methods of surgical intervention, such as screws, hooks, wires, and combinations of the aforementioned, none of which have garnered unanimous support as being most effective. The report by Buck3 served to popularize the use of intralaminar screwing for fixation, and the 93% success rate reported in that study has since been corroborated, with several studies reporting rates from 82% to 100%1,3,4. This technique offers a low-profile solution that is motion-sparing with demonstrable stability and mechanical advantage compared with other techniques5 and has been shown to be a more stable method of fixation that can correct relatively large defects, showing efficacy with defects 4 mm and larger5. This procedure is performed by (1) placing the patient in a prone position with minimization of lordosis on the operating table and use of fluoroscopy to localize the defect. (2) A midline incision (approximately 5 cm) is made just lateral to the corresponding spinous process in order to expose the lamina and the defect. (3) A curet is used to clean the defect. (4) Under fluoroscopy, and alternating between anteroposterior and lateral views, a percutaneous stab is made if needed using a 4.5-mm cannulated screw guidewire, and the wire is drilled through the caudal laminar surface, bisecting the pedicle to the superior cortex of the pedicle. (5) A 3.2-mm cannulated drill is then used to drill over the guidewire. (6) The wire is removed, and a ball-tip probe is used to feel the cortices. The screw length is measured and tapped. (7) The lamina is distally overdrilled if it is large enough. (8) A solid (rather than cannulated) screw of appropriate size (usually 4.5-mm diameter) is inserted with compression as needed. (9) If necessary, autologous posterior iliac crest bone graft is obtained from the same incision, and cancellous graft is placed in the defect. (10) A corticocancellous strip is overlaid from the lamina to the transverse process.

Brachial Artery Pseudoaneurysm After Supracondylar Humerus Fracture: A Case Report.

CASE: A 9-year-old boy with a widely displaced Type-III supracondylar humerus fracture presented with a painful mass at the antecubital fossa after pin fixation. Exploration of the mass caused bleeding from a brachial artery pseudoaneurysm that necessitated repair with a saphenous vein graft. Six weeks later, the fracture had healed without complications. CONCLUSION: We describe an unusual presentation of a pediatric supracondylar humerus fracture that highlights the importance of including vascular injury in the differential diagnosis for similar presentations.

Radiographic assessments of pediatric supracondylar fractures and mid-term patient-reported outcomes.

Radiographic parameters are commonly used to determine the need for surgical supracondylar humeral (SCH) fracture reduction and the postoperative quality of reduction. We studied whether such parameters are correlated with mid-term patient-reported outcome (PRO) scores in pediatric patients.We retrospectively reviewed data from 213 patients (104 girls) treated surgically for Gartland type-II (n = 84) or type-III (n = 129) SCH fractures from 2008-2016. Mean (± standard deviation) age at surgery was 5.1 ±â€Š2.1 years. Mean time from initial treatment to outcome survey completion was 5.0 ±â€Š2.1 years (range, 2.0-10 years). We evaluated preoperative radiographs for coronal/sagittal fracture displacement, presence of impaction/comminution, Gartland classification, and rotation. Patients, parents were asked via telephone to complete the QuickDASH (Quick Disability of the Arm, Shoulder, and Hand) and PROMIS (Patient-Reported Outcomes Measurement Information System) Strength Impact, Upper Extremity, and Pain Interference questionnaires. Parents were also asked whether the previously fractured arm appeared normal or abnormal. We evaluated postoperative radiographs for coronal/sagittal deformity, Baumann angle, and rotation and classified reductions as near complete/complete or incomplete. Anterior humeral line through the capitellum, Baumann angle in the 7.5th to 92.5th percentile of the sample, or rotation ratio between 0.85 and 1.15 were considered near complete/complete reductions; all others were considered incomplete. Bivariate analysis was used to determine whether radiographic parameters and arm appearance were associated with QuickDASH and PROMIS scores.Patients with Gartland type-III fractures had significantly greater disability on the QuickDASH at follow-up compared with those with Gartland type-II fractures (P < .01). It is unknown if this statistical difference translates to clinical relevance. No other preoperative or postoperative radiographic parameter was significantly associated with PRO scores. There was no association between fractured arm appearance at follow-up and PRO scores.Radiographic parameters that are used to evaluate the need for and quality of pediatric SCH fracture reduction are not significantly associated with mid-term PROMIS and QuickDASH scores.LOE: Prognostic Level III.

Opioid prescribing practices after posterior spinal arthrodesis for adolescent idiopathic scoliosis.

STUDY DESIGN: Retrospective review. OBJECTIVE: To identify national trends in postoperative opioid prescribing practices after posterior spinal fusion (PSF) in patients with adolescent idiopathic scoliosis (AIS). Opioids are an important component of pain management after PSF for AIS. Given the national opioid crisis, it is important to understand opioid prescribing practices in these patients. METHODS: Using a commercial prescription drug claims database, we identified AIS patients who underwent PSF from 2010 to 2016 and who were prescribed opioids postoperatively. An initial prescription at hospital discharge of ≥ 90 morphine milligram equivalents daily (MMED) was used to identify patients at risk of overdose according to the US Centers for Disease Control and Prevention (CDC) guidelines. Prescriptions for skeletal muscle relaxants were also identified. α = 0.05. RESULTS: We included 3762 patients (75% female) with a mean (± standard deviation) age of 15 ± 2.1 years. 56% of patients filled only 1 opioid prescription after discharge, and 44% had ≥ 1 refills. 91% of opioid prescriptions were for hydrocodone (median strength, 43 MMED; mean strength, 65 ± 270 MMED) or oxycodone formulations (median strength, 60 MMED; mean strength, 79 ± 174 MMED). 82% of prescriptions complied with CDC guidelines (< 90 MMED). Overall, 612 patients (16%) filled ≥ 1 prescription for skeletal muscle relaxants, the most common being cyclobenzaprine (45%) and methocarbamol (29%). The percentage of patients filling > 1 prescription declined from 54% in 2010 to 31% in 2016 (p < 0.001). The proportion of patients receiving prescriptions for ≥ 90 MMED was highest in the West (29%) and lowest in the South (16%) (p < 0.001). CONCLUSION: Most opioid prescriptions after PSF in patients with AIS comply with CDC guidelines. Temporal and geographic variations show an opportunity for standardizing opioid prescribing practices in these patients. LEVEL OF EVIDENCE: III.

Correction to: Opioid prescribing practices after posterior spinal arthrodesis for adolescent idiopathic scoliosis.

The original version of this article unfortunately contained a mistake.