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1.
J Arthroplasty ; 39(5): 1341-1347, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38043744

RESUMEN

BACKGROUND: Femoral nerve (FN) injury is noted as a serious neurological complication following total hip arthroplasty performed via a direct anterior approach (DAA). Therefore, we aimed to clarify the anatomical course of the FN around the acetabular rim and in relation to retractor placement during DAA. METHODS: According to standard protocol, a DAA for total hip arthroplasty was performed on 69 hemipelves from formalin-preserved full-body donors. The surgery was halted after retractor placement at the anterior part of the acetabulum. Then dissection was performed to expose the FN and the iliopsoas muscle. Various measurements were taken using a reference line from the anterior superior iliac spine to the acetabulum's center. A total of 6 measurement points, one every 30° from 0° to 150° along the reference line were used to determine the association between the FN and the retractor tip (RT) and the anterior acetabular rim. RESULTS: The mean distance from the RT to the FN was 22.5 millimeters (mm). The distance from the FN to the anterior acetabular rim decreased from 0 to 90°, where it was 18.8 mm, before increasing again to 27.3 mm at 150°. CONCLUSIONS: In our cadaveric study, the FN was within 11 to 36 mm of the RT. Second, we found the FN to be closest to the anterior acetabular rim at 90° and 120°. Accordingly, special care should be taken during retractor placement, and if possible, placement at 90° and 120° avoided.

2.
J Arthroplasty ; 39(4): 1088-1092, 2024 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-37918488

RESUMEN

BACKGROUND: Iatrogenic vascular injury during total hip arthroplasty (THA) is rare, reported at rates of 0.05 to 0.3%, but a potentially limb-threatening and life-threatening complication. We aimed to describe safe and danger zones for the superior gluteal vessel bundle (SGV bundle) with reference to different THA approaches. METHODS: There were 27 formalin-fixed cadavers with 49 hemipelves dissected. The course and distribution of the SGV bundle were investigated with the help of anatomical landmarks like the greater trochanter, the iliac tubercle (IT), and the ischial tuberosity. RESULTS: We found and exposed the SGV bundle in all 49 specimens with no sex-specific differences. No SGV bundle was encountered up to 28 mm from the greater trochanter and up to 16 mm below the IT. The zone with the highest probability of finding the vessels was 25 to 65 mm below the IT in 39 (80%) cases - defining a danger zone (in relation to the skin incision) in the proximal fourth for the direct anterior approach, in the proximal half for the antero-lateral approach, in the proximal fifth for the direct lateral approach, and almost no danger zone for the posterior approach. CONCLUSIONS: Special care in proximal instrument placement should be taken during THA. When extending one of the surgical approaches, manipulations in the proximal, cranial surgical window should be performed with the utmost care to avoid SGV bundle injury.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Lesiones del Sistema Vascular , Humanos , Nalgas/cirugía , Cadáver , Fémur , Lesiones del Sistema Vascular/etiología , Lesiones del Sistema Vascular/prevención & control
3.
Semin Musculoskelet Radiol ; 27(2): 129-135, 2023 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-37011614

RESUMEN

Profound knowledge of nerve variations is essential for clinical practice. It is crucial for interpreting the large variability of a patient's clinical presentation and the different mechanisms of nerve injury. Awareness of nerve variations facilitates surgical safety and efficacy. Clinically significant anatomical variations can be classified into two main groups: variability in the course of the nerve and variability of structures surrounding the nerve. In this review article we focus on the most common nerve variants of the upper extremity and their clinical relevance.


Asunto(s)
Nervios Periféricos , Extremidad Superior , Humanos , Extremidad Superior/diagnóstico por imagen , Extremidad Superior/cirugía , Extremidad Superior/inervación , Nervios Periféricos/diagnóstico por imagen , Nervios Periféricos/cirugía , Variación Anatómica
4.
J Anat ; 240(2): 376-384, 2022 02.
Artículo en Inglés | MEDLINE | ID: mdl-34697796

RESUMEN

The functions of the subclavius muscle (SM) are described as stabilization of the sternoclavicular joint (SCJ) and resisting elevation of the lateral end of the clavicle. During systematic cadaveric dissections, we observed additional fibrous structures, previously described as variants of the anatomy, extending from the SM and inserting into the coracoid process (CP). Due to the high incidence of these structures in our dissections, we hypothesized that the attachment at the CP is more common than appreciated and that, as a corollary, the function of the SM was (or has been) more complex than simply depressing the clavicle and generating stability at the SCJ. For our investigation, fifty-two upper extremities of 26 human cadavers were dissected. The SM was demonstrated from costal to clavicular attachment. We documented additional fibrous structures apparently derived from the SM inserting into the CP. Measurements of the length of the SM, the length of its attachment, and the length of the clavicle were taken in situ, with the specimens supine and the upper extremity in the anatomical position. Variations in the anatomy of the SM and its coracoidal attachment were recorded, and potential correlations were investigated. For documentation purposes photographs and video sequences of passive motion of the shoulder girdle of the specimens were taken. In 49 of the 52 specimens we found additional fibrous structures passing from the SM to the CP. We differentiated three types: (1) a strong cord-like structure; (2) a small or thin cord-like structure or structures; and (3) a planar twisted sheet-like structure. The SM and its extension to the CP appears to contribute to a 'functional scapular suspension system' together with the other muscles enveloped by the clavipectoral fascia (pectoralis minor, coracobrachialis and the short head of the biceps brachii). This system assists in the control of the position of the scapula in relation to the thorax, particularly in elevated positions of the upper extremity. We speculate that the differentiation of the fibrous structure depends on the functional demands of the individual. Level of Evidence: Basic science study.


Asunto(s)
Músculos Pectorales , Hombro , Cadáver , Clavícula/fisiología , Apófisis Coracoides/anatomía & histología , Humanos , Escápula/anatomía & histología
5.
J Arthroplasty ; 36(3): 1138-1142, 2021 03.
Artículo en Inglés | MEDLINE | ID: mdl-33071031

RESUMEN

BACKGROUND: During primary and revision total hip arthroplasty (THA) lesions of the superior gluteal nerve (SGN) can substantially compromise patient outcome. For the primary direct anterior approach (DAA) and its proximal approach extensions, especially the muscular branch entering the tensor fasciae latae (TFL) muscle is at risk. SGN lesions can result in fatty atrophy and functional loss of the TFL. Therefore, the course and branching pattern of the SGN were examined and related to the DAA and its proximal approach extension. The aim of the study is to describe safe and danger zones for the SGN with regard to the DAA and its proximal extensions. METHODS: Twenty-five formalin-fixed cadavers with 48 hemipelves were dissected. The course, distribution, and branching pattern of the SGN and its muscular branch inserting into the TFL muscle were investigated with regard to the DAA with the help of anatomical landmarks like the greater trochanter and the iliac tubercle. RESULTS: In 72.9% of the specimens the SGN passed the greater sciatic foramen superior to the piriformis muscle with one main trunk. The muscular branch of the SGN supplying the TFL divided from the main branch in 89.6% of the specimens at the level of the greater sciatic foramen. Before entering the TFL muscle the muscular branch showed a variable branching pattern in the interval between the gluteus medius and minimus. A danger zone for the SGN with regard to the DAA was found in the proximal fourth of the skin incision. CONCLUSION: Special care in proximal instrument placement should be taken during the DAA. When extending the DAA proximally manipulations in the proximal, caudal surgical window should be performed with the utmost care.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Hepatitis C Crónica , Artroplastia de Reemplazo de Cadera/efectos adversos , Nalgas , Cadera , Humanos , Músculo Esquelético/cirugía , Reoperación
6.
J Arthroplasty ; 36(1): 368-373, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-32826147

RESUMEN

BACKGROUND: Although the direct anterior approach (DAA) has become a standard for primary and revision total hip arthroplasty, it involves a high risk of injuring the lateral femoral cutaneous nerve (LFCN). The aim of this study is to examine the course of the LFCN in relation to various skin incisions and approach extensions used for the DAA. METHODS: We obtained 44 limbs and hemipelves from 22 formalin-preserved cadavers, in which LFCN was identified. All nerve branches of the LFCN were carefully traced. The branching pattern and the distribution in the thigh were described in relation to the standard approach for primary total hip arthroplasty, the skin crease bikini incision, the longitudinal extension, and the lazy S extension of the DAA. RESULTS: We found 31 (70.5%) Sartorius-type, 6 (13.6%) posterior-type, and 7 (15.9%) fan-type branching patterns of the LFCN. We observed 2.02 branches per hemipelvis. All fan-type LFCNs had 3 or more than 3 branches. We found that the main branch of the LFCN was medial to the primary DAA approach as well as to the lazy S extended DAA approach. The bikini incision and the incision for the longitudinal extension of the DAA crosses the main branch of the LFCN in 100% of cases. CONCLUSION: The fan-type pattern of the LFCN might be harmed by all skin incisions. Chances are high that LFCN branches could be jeopardized with a bikini-type incision and the longitudinal extension of the DAA. The risk of jeopardizing the LFCN with a lazy S-type distal extension is reduced.


Asunto(s)
Artroplastia de Reemplazo de Cadera , Hepatitis C Crónica , Artroplastia de Reemplazo de Cadera/efectos adversos , Nervio Femoral , Humanos , Reoperación , Muslo
7.
Clin Anat ; 34(7): 1059-1067, 2021 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-33580897

RESUMEN

INTRODUCTION: One of the transitional zones of the human body is situated in the cervix uteri. The developmental differentiation of epithelial and stromal characteristics in such a region is of high clinical interest. However, few studies have focused on the development of this region, and information in anatomical and clinical textbooks is limited. We therefore examined the development of the human vaginal fornix and the cervix uteri during prenatal development. MATERIALS AND METHODS: We examined 29 female embryos and fetuses between 20 and 34 weeks and two newborns using histology and immunohistochemistry. RESULTS: The characteristic shape of the portiocervicis and the vaginal fornix first became visible in mid-term fetuses because of the different muscular coats and of an uncategorized Müllerian-derived epithelium, which was rapidly replaced by a multilayered squamous epithelium. Only thereafter, in older fetuses, were there organogenetic differentiation of the epithelia and the underlying stroma of the cervical canal. UGS-derived p63/CK17-positive cells could be identified as precursor cells for the squamous epithelium, and Müllerian-derived CK7-positive cells for the columnar-type epithelium. Both cell types and different stromal zones were already present in a prenatal transformation zone. Initial functional differentiation could be observed in perinatal stages. CONCLUSIONS: Our results on prenatal human development strongly support the view that two different cell lineages meet at the transitional zone of the cervix uteri and that these lineages depend on alternative signals from the underlying stromal compartment.


Asunto(s)
Cuello del Útero/embriología , Vagina/embriología , Diferenciación Celular , Células Epiteliales , Femenino , Feto , Humanos , Recién Nacido
8.
Arch Orthop Trauma Surg ; 140(10): 1395-1401, 2020 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-32108254

RESUMEN

PURPOSE: The aim of this study was to assess the biomechanical properties of intact vertebra augmented using a local osteo-enhancement procedure to inject a triphasic calcium sulfate/calcium phosphate implant material. METHODS: Twenty-one fresh frozen human cadaver vertebra (Th11-L2) were randomized into three groups: treatment, sham, and control (n = 7 each). Treatment included vertebral body access, saline lavage to displace soft tissue and marrow elements, and injection of the implant material to fill approximately 20% of the vertebral body by volume. The sham group included all treatment steps, but without injection of the implant material. The control group consisted of untreated intact osteoporotic vertebra. Load at failure and displacement at failure for each of the three groups were measured in axial compression loading. RESULTS: The mean failure load of treated vertebra (4118 N) was significantly higher than either control (2841 N) or sham (2186 N) vertebra (p < 0.05 for: treatment vs. control, treatment vs. sham). Treated vertebra (1.11 mm) showed a significantly higher mean displacement at failure than sham vertebra (0.80 mm) (p < 0.05 for: treatment vs. sham). In the control group, the mean displacement at failure was 0.99 mm. CONCLUSIONS: This biomechanical study shows that a local osteo-enhancement procedure using a triphasic implant material significantly increases the load at failure and displacement at failure in cadaveric osteoporotic vertebra.


Asunto(s)
Sustitutos de Huesos/farmacología , Osteoporosis/fisiopatología , Columna Vertebral , Fenómenos Biomecánicos , Fosfatos de Calcio/farmacología , Sulfato de Calcio/farmacología , Humanos , Columna Vertebral/efectos de los fármacos , Columna Vertebral/fisiopatología , Soporte de Peso
9.
Arch Orthop Trauma Surg ; 138(3): 419-425, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29177540

RESUMEN

INTRODUCTION: Gluteal insufficiency is of concern with lateral approaches to total hip arthroplasty. Damage to the branches of the superior gluteal nerve may cause degeneration of the innervated muscles. The direct anterior approach exploits the intermuscular and internerval interval between tensor fasciae latae laterally and sartorius and rectus femoris muscle medially. In this study, the distance of the superior gluteal nerve in relation to anatomical landmarks was determined. MATERIALS AND METHODS: Two experienced surgeons implanted trial components in 15 alcohol glycerol fixed cadavers with 30 hips. The trials were removed, and the main branch of the superior gluteal nerve and muscular branches of the nerve were exposed from lateral. RESULTS: No visual damage to the main nerve branches and the location of the nerve in relation to the greater trochanter were noted by an experienced surgeon. The superior gluteal nerve and its muscular branches crossed the muscular interval between the gluteus medius and tensor fasciae latae muscles at a mean distance of 39 mm from the tip of the greater trochanter. CONCLUSIONS: The direct anterior approach for total hip arthroplasty minimizes the risk of injuring the superior gluteal nerve, which may result in a gluteal insufficiency. Special care should be paid on avoiding overstretching the tensor fasciae latea muscle using minimum force on retractors during surgery and by taking care of the entrance point of the superior gluteal nerve to the tensor fasciae latae.


Asunto(s)
Nalgas/inervación , Plexo Lumbosacro/anatomía & histología , Puntos Anatómicos de Referencia , Artroplastia de Reemplazo de Cadera , Cadáver , Femenino , Humanos , Masculino , Traumatismos de los Nervios Periféricos/prevención & control
10.
Eur Radiol ; 27(5): 2225-2234, 2017 May.
Artículo en Inglés | MEDLINE | ID: mdl-27655306

RESUMEN

OBJECTIVES: Differences in noise and density values in MDCT images obtained using ultra-low doses with FBP, ASIR, and MBIR may possibly affect implant site density analysis. The aim of this study was to compare density and noise measurements recorded from dental implant sites using ultra-low doses combined with FBP, ASIR, and MBIR. METHODS: Cadavers were scanned using a standard protocol and four low-dose protocols. Scans were reconstructed using FBP, ASIR-50, ASIR-100, and MBIR, and either a bone or standard reconstruction kernel. Density (mean Hounsfield units [HUs]) of alveolar bone and noise levels (mean standard deviation of HUs) was recorded from all datasets and measurements were compared by paired t tests and two-way ANOVA with repeated measures. RESULTS: Significant differences in density and noise were found between the reference dose/FBP protocol and almost all test combinations. Maximum mean differences in HU were 178.35 (bone kernel) and 273.74 (standard kernel), and in noise, were 243.73 (bone kernel) and 153.88 (standard kernel). CONCLUSIONS: Decreasing radiation dose increased density and noise regardless of reconstruction technique and kernel. The effect of reconstruction technique on density and noise depends on the reconstruction kernel used. KEY POINTS: • Ultra-low-dose MDCT protocols allowed more than 90 % reductions in dose. • Decreasing the dose generally increased density and noise. • Effect of IRT on density and noise varies with reconstruction kernel. • Accuracy of low-dose protocols for interpretation of bony anatomy not known. • Effect of low doses on accuracy of computer-aided design models unknown.


Asunto(s)
Implantes Dentales , Tomografía Computarizada Multidetector/métodos , Algoritmos , Cadáver , Humanos , Modelos Teóricos , Dosis de Radiación , Interpretación de Imagen Radiográfica Asistida por Computador/métodos
11.
Neurourol Urodyn ; 36(4): 1069-1075, 2017 04.
Artículo en Inglés | MEDLINE | ID: mdl-27490402

RESUMEN

AIMS: The aim was to develop a new laparoscopic technique for placement of a pudendal lead. METHODS: Development of a direct, feasible and reliable minimal-invasive laparoscopic approach to the pudendal nerve (PN). Thirty-one embalmed human specimens were dissected for the relevant anatomic structures of the pelvis. Step-by-step documentation and analysis of the laparoscopic approach in order to locate the PN directly in its course around the medial part of the sacrospinous ligament and test this approach for feasibility. Landmarks for intraoperative navigation towards the PN as well as the possible position of an lead were selected and demonstrated. RESULTS: The visible medial umbilical fold, the intrapelvine part of the internal pudendal artery, the coccygeus muscle and the sacrospinous ligament are the main landmarks. The PN traverses the medial part of the sacrospinous ligament dorsally, medially to the internal pudendal artery. The medial part of the sacrospinous ligament has to be exposed in order to display the nerve. An lead can be placed ventrally on the nerve or around it, depending on the lead type or shape. CONCLUSIONS: A precise and reliable identification of the PN by means of laparoscopy is feasible with an easy four-step approach: (1) identification of the medial umbilical fold; (2) identification of the internal iliac artery; (3) identification of the internal pudendal artery and incision of the coccygeus muscle ('white line', arcuated line); and (4) exposition of the medial part of the sacrospinous ligament to display the PN.


Asunto(s)
Terapia por Estimulación Eléctrica , Electrodos Implantados , Laparoscopía , Implantación de Prótesis/métodos , Nervio Pudendo/cirugía , Cadáver , Estudios de Factibilidad , Humanos , Pelvis/anatomía & histología , Pelvis/cirugía , Nervio Pudendo/anatomía & histología
12.
Arch Orthop Trauma Surg ; 137(12): 1755-1760, 2017 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-29032422

RESUMEN

INTRODUCTION: Surgical approaches through smaller incisions reveal less of the underlying anatomy, and therefore, detailed knowledge of the local anatomy and its variations is important in minimally invasive surgery. The aim of this study was to determine the location, extension, and histomorphology of the deep layer of the iliotibial band during minimally invasive hip surgery using the direct anterior approach (DAA). MATERIALS AND METHODS: The morphology of the iliotibial tract was determined in this cadaver study on 40 hips with reference to the anterior superior iliac spine and the tibia. The deep layer of the tractus iliotibialis was exposed up to the hip-joint capsule and length and width measurements taken. Sections of the profound iliotibial tract were removed from the hips and the thickness of the sections was determined microscopically after staining. RESULTS: The superficial tractus iliotibialis had a length of 50.1 (SD 3.8) cm, while tensor fasciae latae total length was 18 (SD 2) cm [unattached 15 (SD 2.5) cm]. Length and width of the deep layer of the tractus iliotibialis were 10.4 (SD 1.3) × 3.3 (SD 0.6) cm. The deep iliotibial band always extended from the distal part of the tensor fascia latae (TFL) muscle to the lateral part of the hip capsule (mean maximum thickness 584 µm). Tractus iliotibialis deep layer morphology did not correlate to other measurements taken (body length, thigh length, and TFL length). CONCLUSIONS: The length of the deep layer is dependent on the TFL, since the profound part of the iliotibial band reaches from the TFL to the hip-joint capsule. The deep layer covers the hip-joint capsule, rectus, and lateral vastus muscles in the DAA interval. To access the precapsular fat pad and the hip-joint capsule, the deep layer has to be split in all approaches that use the direct anterior interval.


Asunto(s)
Artroplastia de Reemplazo de Cadera/métodos , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Músculo Esquelético/anatomía & histología , Anciano , Anciano de 80 o más Años , Cadáver , Fascia/anatomía & histología , Fasciotomía , Femenino , Articulación de la Cadera/cirugía , Humanos , Masculino , Persona de Mediana Edad , Músculo Esquelético/cirugía , Muslo
13.
Surg Radiol Anat ; 39(4): 455-459, 2017 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-27561741

RESUMEN

We describe the heart from a 79-year-old woman with no medical history of cardiac complaints. Her heart shows a regular right coronary artery (RCA) and a variant left coronary artery (LCA) arising from the right sinus of Valsalva. The common stem of the RCA and the LCA is extremely short. The LCA depicts a preinfundibular course with a cranial-anterior loop and reaches the intersection of the anterior interventricular sulcus and the left coronary sulcus, where it divides into the regular branches, the anterior interventricular branch (left anterior descending, LAD) and the circumflex branch (left circumflex, LCx). All further branching resembles a normal distribution with the posterior interventricular branch coming for the RCA. Such a variant LCA is extremely rare with a reported incidence of 0.17 %. However, recognition and angiographic demonstration of such a variation assume the highest priority in a patient undergoing, for instance, direct coronary artery surgery or prosthetic valve replacement.


Asunto(s)
Variación Anatómica , Anomalías de los Vasos Coronarios/diagnóstico , Vasos Coronarios/anatomía & histología , Anciano , Cadáver , Angiografía por Tomografía Computarizada/métodos , Angiografía Coronaria/métodos , Disección , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador
14.
Arch Orthop Trauma Surg ; 136(3): 345-51, 2016 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-26749332

RESUMEN

INTRODUCTION: Osteoporotic hip fractures are an increasing problem in an ageing population. They result in high morbidity, mortality and high socioeconomic costs. For patients with poor bone quality, prophylactic augmentation of the proximal femur might be an option for fracture prevention. METHODS: In two groups of paired human femora the potential of limited polymethyl-methacrylate (PMMA) augmentation (11-15 ml) in a V-shape pattern and the insertion of a proximal femur nail antirotation (PFNA) blade were investigated. The testing was carried out pair wise simulating the single leg stand. The untreated femur in each pair served as control. An axial load was applied until failure. Load displacement parameters and temperature increase during the augmentation process were recorded. RESULTS: In the PMMA group no significant difference was found between the augmented and non-augmented specimen concerning load to failure (p = 0.35) and energy to failure (p = 0.9). A median temperature increase of 9.5 °C was observed in the augmented specimen. A significant correlation was found between the amount of applied PMMA and the temperature increase (Cor. Coef. = 0.82, p = 0.042). In the PFNA group, a significant decrease of load to failure and a non-significant decrease of energy to failure were observed (p = 0.037 and p = 0.075). CONCLUSION: Limited V-shaped PMMA augmentation and PFNA blade insertion did not show any improvement in failure load or energy to failure. Volumes of up to 15 ml PMMA did not cause a critical surface temperature increase.


Asunto(s)
Cementos para Huesos/uso terapéutico , Clavos Ortopédicos , Fracturas del Cuello Femoral/cirugía , Cuello Femoral/cirugía , Fracturas Osteoporóticas/cirugía , Polimetil Metacrilato/uso terapéutico , Anciano , Anciano de 80 o más Años , Fenómenos Biomecánicos , Densidad Ósea , Cadáver , Femenino , Fracturas de Cadera/cirugía , Humanos , Masculino , Modelos Anatómicos
15.
Dentomaxillofac Radiol ; 52(3): 20220387, 2023 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-36688730

RESUMEN

OBJECTIVES: As-low-as-diagnostically-acceptable (ALADA) doses are substantially lower than current diagnostic reference levels. To improve dose management, a reference quality approach was tested in which phantom quality metrics of a clinical ALADA dose reference protocol were used to benchmark potential ALADA dose protocols for various scanner models. METHODS: Spatial resolution, contrast resolution, contrast-to-noise ratio (CNR) and subjective noise and sharpness were evaluated for a clinical ALADA dose reference protocol at 80 kV and 40 mA (CTDIvol 2.66 mGy) and compared with test protocols of two CT scanners at 100 kV and 35 mA (3.08-3.44 mGy), 80 kV and 54-61 mA (2.65 mGy), 80 kV and 40 mA (1.73-1.92 mGy), and 80 kV and 21-23 mA (1.00-1.03 mGy) using different kernels, filtered backprojection and iterative reconstructions. The test protocols with the lowest dose showing quality metrics non-inferior to the reference protocol were verified in a cadaver study by determining the diagnostic accuracy of detection of maxillofacial fractures and CNR of the optical nerve and rectus inferior muscle. RESULTS: 36 different image series were analysed in the phantom study. Based on the phantom quality metrics, potential ALADA dose protocols at 1.73-1.92 mGy were selected. Compared with the reference images, the selected protocols showed non-inferiority in the detection and classification of maxillofacial fractures and non-inferior CNR of orbital soft tissues in the cadaver study. CONCLUSIONS: Reference quality metrics from clinical ALADA dose protocols may be used to guide selection of potential ALADA dose protocols of different CT scanners.


Asunto(s)
Traumatismos Maxilofaciales , Tomografía Computarizada por Rayos X , Humanos , Dosis de Radiación , Tomografía Computarizada por Rayos X/métodos , Fantasmas de Imagen , Cadáver , Interpretación de Imagen Radiográfica Asistida por Computador/métodos
16.
Diagnostics (Basel) ; 13(7)2023 Mar 23.
Artículo en Inglés | MEDLINE | ID: mdl-37046438

RESUMEN

Ionizing radiation is necessary for diagnostic imaging and deciding the right radiation dose is extremely critical to obtain a decent quality image. However, increasing the dosage to improve the image quality has risks due to the potential harm from ionizing radiation. Thus, finding the optimal as low as diagnostically acceptable (ALADA) dosage is an open research problem that has yet to be tackled using artificial intelligence (AI) methods. This paper proposes a new multi-balancing 3D convolutional neural network methodology to build 3D multidetector computed tomography (MDCT) datasets and develop a 3D classifier model that can work properly with 3D CT scan images and balance itself over the heavy unbalanced multi-classes. The proposed models were exhaustively investigated through eighteen empirical experiments and three re-runs for clinical expert examination. As a result, it was possible to confirm that the proposed models improved the performance by an accuracy of 5% to 10% when compared to the baseline method. Furthermore, the resulting models were found to be consistent, and thus possibly applicable to different MDCT examinations and reconstruction techniques. The outcome of this paper can help radiologists to predict the suitability of CT dosages across different CT hardware devices and reconstruction algorithms. Moreover, the developed model is suitable for clinical application where the right dose needs to be predicted from numerous MDCT examinations using a certain MDCT device and reconstruction technique.

17.
Anat Sci Educ ; 16(5): 814-829, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37183973

RESUMEN

Hands-on courses utilizing preserved human tissues for educational training offer an important pathway to acquire basic anatomical knowledge. Owing to the reevaluation of formaldehyde limits by the European Commission, a joint approach was chosen by the German-speaking anatomies in Europe (Germany, Austria, Switzerland) to find commonalities among embalming protocols and infrastructure. A survey comprising 537 items was circulated to all anatomies in German-speaking Europe. Clusters were established for "ethanol"-, formaldehyde-based ("FA"), and "other" embalming procedures, depending on the chemicals considered the most relevant for each protocol. The logistical framework, volumes of chemicals, and infrastructure were found to be highly diverse between the groups and protocols. Formaldehyde quantities deployed per annum were three-fold higher in the "FA" (223 L/a) compared to the "ethanol" (71.0 L/a) group, but not for "other" (97.8 L/a), though the volumes injected per body were similar. "FA" was strongly related to table-borne air ventilation and total fixative volumes ≤1000 L. "Ethanol" was strongly related to total fixative volumes >1000 L, ceiling- and floor-borne air ventilation, and explosion-proof facilities. Air ventilation was found to be installed symmetrically in the mortuary and dissection facilities. Certain predictors exist for the interplay between the embalming used in a given infrastructure and technical measures. The here-established cluster analysis may serve as decision supportive tool when considering altering embalming protocols or establishing joint protocols between institutions, following a best practice approach to cater toward best-suited tissue characteristics for educational purposes, while simultaneously addressing future demands on exposure limits.


Asunto(s)
Anatomía , Humanos , Fijadores , Anatomía/educación , Embalsamiento/métodos , Cadáver , Formaldehído/química , Etanol
18.
Int J Comput Assist Radiol Surg ; 17(2): 261-270, 2022 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-34792744

RESUMEN

PURPOSE: An auditory brainstem implant (ABI) represents an alternative for patients with profound hearing loss who are constrained from receiving a cochlear implant. The positioning of the ABI electrode influences the patient's auditory capacity and, therefore, quality of life and is challenging even with available intraoperative electrophysiological monitoring. This work aims to provide and assess the feasibility of visual-spatial assistance for ABI positioning. METHODS: The pose of the forceps instrument that grasps the electrode was electromagnetically navigated and interactively projected in the eyepieces of a surgical microscope with respect to a target point. Intraoperative navigation was established with an experimental technique for automated nasopharyngeal patient registration. Two ABI procedures were completed in a human specimen head. RESULTS: An intraoperative usability study demonstrated lower localization error when using the proposed visual display versus standard cross-sectional views. The postoperative evaluations of the preclinical study showed that the center of the electrode was misplaced to the planned position by 1.58 mm and 3.16 mm for the left and the right ear procedure, respectively. CONCLUSION: The results indicate the potential to enhance intraoperative feedback during ABI positioning with the presented system. Further improvements consider estimating the pose of the electrode itself to allow for better orientation during placement.


Asunto(s)
Implantación Auditiva en el Tronco Encefálico , Estudios Transversales , Estudios de Factibilidad , Humanos , Calidad de Vida , Resultado del Tratamiento
19.
Diagnostics (Basel) ; 11(10)2021 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-34679601

RESUMEN

OBJECTIVE: Repeated computed tomography (CT) is essential for diagnosis, surgical planning and follow-up in patients with middle and inner ear pathology. Dose reduction to "as low as diagnostically acceptable" (ALADA) is preferable but challenging. We aimed to compare the diagnostic quality of images of subtle temporal bone structures produced with low doses (LD) and reference protocols (RP). METHODS: Two formalin-fixed human cadaver heads were scanned using a 64-slice CT scanner and cone-beam CT (CBCT). The protocols were: RP (120 kV, 250 mA, CTDIvol 83.72 mGy), LD1 (100 kV, 80 mA, CTDIvol 26.79 mGy), LD2 (100 kV, 35 mA, CTDIvol 7.66 mGy), LD3 (80 kV, 40 mA, CTDIvol 4.82 mGy), and CBCT standard protocol. Temporal bone structures were assessed using a 5-point scale. RESULTS: A median score of ≥2 was achieved with protocols such as the tendons of m. tensor tympani (RP/LD1/LD2/CBCT) and m. stapedius (CBCT), the incudostapedial joint (RP/LD1/CBCT), the incudomalleolar joint (RP/LD1/LD2/CBCT), the stapes feet (RP/LD1/CBCT), the stapes head (RP/LD1/LD2/CBCT), the tympanic membrane (RP/LD1/LD2/CBCT), the lamina spiralis ossea (none), the chorda tympani (RP/LD1/CBCT), and the modiolus (RP/LD1/LD2/CBCT). Adaptive statistical iterative reconstructions did not show advantages over the filtered back projection. CONCLUSIONS: LD protocols using a CTDIvol of 7.66 mGy may be sufficient for the identification of temporal bone structures.

20.
J Orofac Orthop ; 81(6): 427-439, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32897413

RESUMEN

PURPOSE: This study investigates the accuracy of abutment transfer with current impression materials and provides a concise overview, including other relevant factors, in order to enable clinicians to make an informed decision about the optimal impression for this treatment procedure. METHODS: In all, 96 impressions of a cadaver head with two orthodontic miniscrews in place were taken with four common impression materials by two observers and using two methods of application. After pouring with a standard type IV stone and abutment transfer, all models and the upper jaw (which had been separated from the head) were scanned in a standard model scanner (Zirkonzahn® [Zirkohnzahn GmbH, Gais, Italy] S600 ARTI) and evaluated using a computer-aided design (CAD) program (GOM-Inspect [Gesellschaft für optische Messtechnik m.b.H., Braunschweig, Germany]). The deviations were measured at six points per screw and statistically evaluated with SPSS® (IBM, Chicago, IL, USA). RESULTS: Optimal values were obtained with biphasic polyvinylsiloxane, while monophasic polyvinylsiloxane, alginate and polyether also resulted in acceptable accuracy. Observer experience showed no effect and the method of application had only a minor effect on accuracy. CONCLUSIONS: Within the limitations of this study, it seems that all impression materials are suitable for miniscrew abutment transfer, provided that methods of intraoral adaptation of the orthodontic appliance can be employed. If higher accuracy is needed or for clinicians with less experienced, a biphasic polyvinylsiloxane impression with the putty-wash technique should be used as this combination reduces setting time. The most cost-effective version, alginate, can be used if the consequences of greater deviations can be handled. Caution is advised with polyether if undercuts are present.


Asunto(s)
Técnica de Impresión Dental , Modelos Dentales , Materiales de Impresión Dental , Alemania , Italia
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