Búsqueda | Biblioteca Virtual en Salud

1.

Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity.

de Jong, Sanne E; van Unen, Vincent; Manurung, Mikhael D; Stam, Koen A; Goeman, Jelle J; Jochems, Simon P; Höllt, Thomas; Pezzotti, Nicola; Mouwenda, Yoanne D; Betouke Ongwe, Madeleine Eunice; Lorenz, Freia-Raphaella; Kruize, Yvonne C M; Azimi, Shohreh; König, Marion H; Vilanova, Anna; Eisemann, Elmar; Lelieveldt, Boudewijn P F; Roestenberg, Meta; Sim, B Kim Lee; Reinders, Marcel J T; Fendel, Rolf; Hoffman, Stephen L; Kremsner, Peter G; Koning, Frits; Mordmüller, Benjamin; Lell, Bertrand; Yazdanbakhsh, Maria.

Nat Immunol ; 22(5): 654-665, 2021 05.

Artículo Inglés | MEDLINE | ID: mdl-33888898

2.

In vitro production of infectious Plasmodium falciparum sporozoites.

Eappen, Abraham G; Li, Tao; Marquette, Meghan; Chakravarty, Sumana; Kc, Natasha; Zanghi, Gigliola; Hoffman, Benjamin U; Hettiarachchi, Hashani; Patil, Asha; Abebe, Yonas; Tran, Christiane; Yossef, Alemtaye A; McWilliams, Ian; Morrison, Robert D; Rathakrishnan, Ayyappan; Inbar, Ehud; Aly, Ahmed S I; De La Vega, Patricia; Belmonte, Maria; Sedegah, Martha; Wai, Tint; Campo, Joseph J; King, Harley; Kappe, Stefan H I; Li, MingLin; Billingsley, Peter F; Sim, B Kim Lee; Hoffman, Stephen L.

Nature ; 612(7940): 534-539, 2022 12.

Artículo Inglés | MEDLINE | ID: mdl-36477528

3.

Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity.

Mwakingwe-Omari, Agnes; Healy, Sara A; Lane, Jacquelyn; Cook, David M; Kalhori, Sahand; Wyatt, Charles; Kolluri, Aarti; Marte-Salcedo, Omely; Imeru, Alemush; Nason, Martha; Ding, Lei K; Decederfelt, Hope; Duan, Junhui; Neal, Jillian; Raiten, Jacob; Lee, Grace; Hume, Jen C C; Jeon, Jihyun E; Ikpeama, Ijeoma; Kc, Natasha; Chakravarty, Sumana; Murshedkar, Tooba; Church, L W Preston; Manoj, Anita; Gunasekera, Anusha; Anderson, Charles; Murphy, Sean C; March, Sandra; Bhatia, Sangeeta N; James, Eric R; Billingsley, Peter F; Sim, B Kim Lee; Richie, Thomas L; Zaidi, Irfan; Hoffman, Stephen L; Duffy, Patrick E.

Nature ; 595(7866): 289-294, 2021 07.

Artículo Inglés | MEDLINE | ID: mdl-34194041

4.

The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections.

Wichers-Misterek, Jan Stephan; Krumkamp, Ralf; Held, Jana; von Thien, Heidrun; Wittmann, Irene; Höppner, Yannick Daniel; Ruge, Julia M; Moser, Kara; Dara, Antoine; Strauss, Jan; Esen, Meral; Fendel, Rolf; Sulyok, Zita; Jeninga, Myriam D; Kremsner, Peter G; Sim, B Kim Lee; Hoffman, Stephen L; Duffy, Michael F; Otto, Thomas D; Gilberger, Tim-Wolf; Silva, Joana C; Mordmüller, Benjamin; Petter, Michaela; Bachmann, Anna.

PLoS Pathog ; 19(6): e1011468, 2023 06.

Artículo Inglés | MEDLINE | ID: mdl-37384799

5.

Machine learning prediction of malaria vaccine efficacy based on antibody profiles.

Wistuba-Hamprecht, Jacqueline; Reuter, Bernhard; Fendel, Rolf; Hoffman, Stephen L; Campo, Joseph J; Felgner, Philip L; Kremsner, Peter G; Mordmüller, Benjamin; Pfeifer, Nico.

PLoS Comput Biol ; 20(6): e1012131, 2024 Jun.

Artículo Inglés | MEDLINE | ID: mdl-38848436

6.

An efficient single-cell based method for linking human T cell phenotype to T cell receptor sequence and specificity.

Wahl, Ilka; Hoffmann, Sandro; Hundsdorfer, Rebecca; Puchan, Julia; Hoffman, Stephen L; Kremsner, Peter G; Mordmüller, Benjamin; Busse, Christian E; Wardemann, Hedda.

Eur J Immunol ; 52(2): 237-246, 2022 02.

Artículo Inglés | MEDLINE | ID: mdl-34710239

7.

Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence.

Inbar, Ehud; Eappen, Abraham G; Alford, Robert T; Reid, William; Harrell, Robert A; Hosseini, Maryam; Chakravarty, Sumana; Li, Tao; Sim, B Kim Lee; Billingsley, Peter F; Hoffman, Stephen L.

PLoS Pathog ; 17(11): e1009770, 2021 11.

Artículo Inglés | MEDLINE | ID: mdl-34784388

8.

PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controlled human malaria infection.

Murphy, Sean C; Deye, Gregory A; Sim, B Kim Lee; Galbiati, Shirley; Kennedy, Jessie K; Cohen, Kristen W; Chakravarty, Sumana; Kc, Natasha; Abebe, Yonas; James, Eric R; Kublin, James G; Hoffman, Stephen L; Richie, Thomas L; Jackson, Lisa A.

PLoS Pathog ; 17(5): e1009594, 2021 05.

Artículo Inglés | MEDLINE | ID: mdl-34048504

9.

Plasmodium knowlesi in pig-tailed macaques: a potential new model for malaria vaccine research.

Shears, Melanie J; Reynolds, Rebekah A; Duncombe, Caroline J; Watson, Felicia N; Staubus, Weston J; Chavtur, Chris; Seilie, Annette M; Tran, Tuan M; Chakravarty, Sumana; Hoffman, Stephen L; Murphy, Sean C.

Malar J ; 22(1): 379, 2023 Dec 13.

Artículo Inglés | MEDLINE | ID: mdl-38093306

10.

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine.

Mordmüller, Benjamin; Surat, Güzin; Lagler, Heimo; Chakravarty, Sumana; Ishizuka, Andrew S; Lalremruata, Albert; Gmeiner, Markus; Campo, Joseph J; Esen, Meral; Ruben, Adam J; Held, Jana; Calle, Carlos Lamsfus; Mengue, Juliana B; Gebru, Tamirat; Ibáñez, Javier; Sulyok, Mihály; James, Eric R; Billingsley, Peter F; Natasha, K C; Manoj, Anita; Murshedkar, Tooba; Gunasekera, Anusha; Eappen, Abraham G; Li, Tao; Stafford, Richard E; Li, Minglin; Felgner, Phil L; Seder, Robert A; Richie, Thomas L; Sim, B Kim Lee; Hoffman, Stephen L; Kremsner, Peter G.

Nature ; 542(7642): 445-449, 2017 02 23.

Artículo Inglés | MEDLINE | ID: mdl-28199305

11.

Ruth Nussenzweig (1928-2018).

Hoffman, Stephen L.

Immunity ; 48(6): 1061-1062, 2018 Jun 19.

Artículo Inglés | MEDLINE | ID: mdl-33245868

12.

Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites.

Chakravarty, Sumana; Shears, Melanie J; James, Eric R; Rai, Urvashi; Kc, Natasha; Conteh, Solomon; Lambert, Lynn E; Duffy, Patrick E; Murphy, Sean C; Hoffman, Stephen L.

Malar J ; 21(1): 247, 2022 Aug 27.

Artículo Inglés | MEDLINE | ID: mdl-36030292

13.

Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial.

Nouatin, Odilon; Ibáñez, Javier; Fendel, Rolf; Ngoa, Ulysse A; Lorenz, Freia-Raphaella; Dejon-Agobé, Jean-Claude; Edoa, Jean Ronald; Flügge, Judith; Brückner, Sina; Esen, Meral; Theisen, Michael; Hoffman, Stephen L; Moutairou, Kabirou; Luty, Adrian J F; Lell, Bertrand; Kremsner, Peter G; Adegnika, Ayola A; Mordmüller, Benjamin.

Malar J ; 21(1): 191, 2022 Jun 17.

Artículo Inglés | MEDLINE | ID: mdl-35715803

14.

Diagnostic performance and comparison of ultrasensitive and conventional rapid diagnostic test, thick blood smear and quantitative PCR for detection of low-density Plasmodium falciparum infections during a controlled human malaria infection study in Equatorial Guinea.

Mpina, Maxmillian; Stabler, Thomas C; Schindler, Tobias; Raso, Jose; Deal, Anna; Acuche Pupu, Ludmila; Nyakarungu, Elizabeth; Del Carmen Ovono Davis, Maria; Urbano, Vicente; Mtoro, Ali; Hamad, Ali; Lopez, Maria Silvia A; Pasialo, Beltran; Eyang, Marta Alene Owono; Rivas, Matilde Riloha; Falla, Carlos Cortes; García, Guillermo A; Momo, Juan Carlos; Chuquiyauri, Raul; Saverino, Elizabeth; Preston Church, L W; Kim Lee Sim, B; Manguire, Bonifacio; Tanner, Marcel; Maas, Carl; Abdulla, Salim; Billingsley, Peter F; Hoffman, Stephen L; Jongo, Said; Richie, Thomas L; Daubenberger, Claudia A.

Malar J ; 21(1): 99, 2022 Mar 24.

Artículo Inglés | MEDLINE | ID: mdl-35331251

15.

Activation of TCR VÎ´1⁺ and VÎ´1^-VÎ´2^- Î³Î´ T Cells upon Controlled Infection with Plasmodium falciparum in Tanzanian Volunteers.

Rutishauser, Tobias; Lepore, Marco; Di Blasi, Daniela; Dangy, Jean-Pierre; Abdulla, Salim; Jongo, Said; Ramadhani, Kamaka; Sim, B Kim Lee; Hoffman, Stephen L; Tanner, Marcel; Daubenberger, Claudia; De Libero, Gennaro.

J Immunol ; 204(1): 180-191, 2020 01 01.

Artículo Inglés | MEDLINE | ID: mdl-31801816

16.

Multidose Priming and Delayed Boosting Improve Plasmodium falciparum Sporozoite Vaccine Efficacy Against Heterologous P. falciparum Controlled Human Malaria Infection.

Lyke, Kirsten E; Singer, Alexandra; Berry, Andrea A; Reyes, Sharina; Chakravarty, Sumana; James, Eric R; Billingsley, Peter F; Gunasekera, Anusha; Manoj, Anita; Murshedkar, Tooba; Laurens, Matthew B; Church, W Preston; Garver Baldwin, Lindsey S; Sedegah, Martha; Banania, Glenna; Ganeshan, Harini; Guzman, Ivelese; Reyes, Anatalio; Wong, Mimi; Belmonte, Arnel; Ozemoya, Amelia; Belmonte, Maria; Huang, Jun; Villasante, Eileen; Sim, B Kim Lee; Hoffman, Stephen L; Richie, Thomas L; Epstein, Judith E.

Clin Infect Dis ; 73(7): e2424-e2435, 2021 10 05.

Artículo Inglés | MEDLINE | ID: mdl-32920641

17.

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression.

Bachmann, Anna; Bruske, Ellen; Krumkamp, Ralf; Turner, Louise; Wichers, J Stephan; Petter, Michaela; Held, Jana; Duffy, Michael F; Sim, B Kim Lee; Hoffman, Stephen L; Kremsner, Peter G; Lell, Bertrand; Lavstsen, Thomas; Frank, Matthias; Mordmüller, Benjamin; Tannich, Egbert.

PLoS Pathog ; 15(7): e1007906, 2019 07.

Artículo Inglés | MEDLINE | ID: mdl-31295334

18.

Role of human Pegivirus infections in whole Plasmodium falciparum sporozoite vaccination and controlled human malaria infection in African volunteers.

Tumbo, Anneth-Mwasi; Schindler, Tobias; Dangy, Jean-Pierre; Orlova-Fink, Nina; Bieri, Jose Raso; Mpina, Maximillian; Milando, Florence A; Juma, Omar; Hamad, Ali; Nyakarungu, Elizabeth; Chemba, Mwajuma; Mtoro, Ali; Ramadhan, Kamaka; Olotu, Ally; Makweba, Damas; Mgaya, Stephen; Stuart, Kenneth; Perreau, Matthieu; Stapleton, Jack T; Jongo, Said; Hoffman, Stephen L; Tanner, Marcel; Abdulla, Salim; Daubenberger, Claudia.

Virol J ; 18(1): 28, 2021 01 26.

Artículo Inglés | MEDLINE | ID: mdl-33499880

19.

Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections.

Billingsley, Peter F; George, Kasim I; Eappen, Abraham G; Harrell, Robert A; Alford, Robert; Li, Tao; Chakravarty, Sumana; Sim, B Kim Lee; Hoffman, Stephen L; O'Brochta, David A.

Malar J ; 20(1): 284, 2021 Jun 26.

Artículo Inglés | MEDLINE | ID: mdl-34174879

20.

Early whole blood transcriptional responses to radiation-attenuated Plasmodium falciparum sporozoite vaccination in malaria naïve and malaria pre-exposed adult volunteers.

Duffy, Fergal J; Du, Ying; Carnes, Jason; Epstein, Judith E; Hoffman, Stephen L; Abdulla, Salim; Jongo, Said; Mpina, Maxmillian; Daubenberger, Claudia; Aitchison, John D; Stuart, Ken.

Malar J ; 20(1): 308, 2021 Jul 09.

Artículo Inglés | MEDLINE | ID: mdl-34243763

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