[Analysis of disability due to ocular complications of diabetes in Tashkent over a ten-year period]. / Analiz invalidnosti vsledstvie oftal'mologicheskikh oslozhnenii sakharnogo diabeta v Tashkente za desyatiletnii period.

AIM: to study peculiarities of primary and recurrent disability due to ocular complications of diabetes in Tashkent over the years 2003-2012 and to assess the impact of risk factors on the effectiveness of laser photocoagulation of the retina. MATERIAL AND METHODS: A total of 347 disability examination reports of diabetic patients with ocular complications were copied and 48 case histories of patients with type II diabetes who underwent laser photocoagulation of the retina - retrospectively analyzed. Stabilization of visual function was used as the effectiveness criterion. RESULTS: The rate of new cases of disability over the studied decade averaged 0.55 per 100,000 population per year, while that of recurrent disability was 1.8 times higher - 0.97. The overall rate of disability was not high - 1.53; at that, severe disability (i.e. grade I and II) prevailed. Both recurrent and primary disability groups were made up by middle-aged patients and those in their retirement age; however, in the recurrent disability group the number of young disabled people was 4.5 times higher than in the primary disability group. Studies of the effectiveness of laser photocoagulation of the retina in relation to the compensation of diabetes and blood pressure level showed that unstable general condition was associated with not only significant deterioration of visual function, but also complications, including severe. CONCLUSION: The rate of disability due to ocular complications of diabetes is generally not high, however, grades I and II disabilities that require greater social support has been found to prevail in both groups. Most of disabled people are middle-aged (working-age population), which also causes economic damage. In cases of decompensated diabetes and unstable blood pressure, the effectiveness of laser photocoagulation of the retina is reduced.

[To the substantiation of the maximum allowable concentrations of the herbicide dalzlak-T in ambient air].

The paper presents the results of experimental studies of the reflectory and resorptive effects of different concentrations of the herbicide Dalzlak-T in ambient air. Hygienic regulations have been first developed and a hazard class for the agent has been defined to estimate ambient air pollution during its manufacture, storage, transportation, and agricultural application.

[Hygienic assessment of combined action of ambient air pollutions in the localities].

The paper describes the experimental studies dealing with the reflectory and resorptive effects of a gas-vapor-dust-like mixture comprising sulfur dioxide, nitrogen dioxide, hydrogen fluoride, and suspension particles. The combined effect of the mixture when inhaled by animals was ascertained to present as the incomplete summation effect type. In the combined presence in the ambient air, the sum of shares of sulfur dioxide, nitrogen dioxide, hydrogen fluoride, and suspension particles should not be greater than 0.4 MPC of the isolated effect of each agent alone.

[The hygienic standardization of 3-phenoxybenzyl alcohol in the atmospheric air of populated places]. / Gigienicheskoe normirovanie 3-fenoksibenzilovogo spirta v atmosfernom vozdukhe nasellennykh mest.

The threshold level of 3-phenoxybenzyl alcohol (3-PBA) in ambient air was set up at 0.48 mg/m3. Inhalation of 3-PBA in concentrations of 4.86 and 0.518 mg/m3 caused changes in the central nervous system, metabolic processes, liver function, reduced the nonspecific resistance of the organism, and had a gonadotoxic effect. The concentration of 0.518 m3 was the threshold one, causing changes in only few of the general toxic parameters, and the 0.059 mg/m3 concentration was noneffective. The maximum permissible concentration (MPC) for 3-PBA upon a single exposure is recommended to be set up at the level of 0.2 mg/m3, the mean daily MPC at 0.06 mg/m3. By its reflex and resorptive effects the agent was referred to hazard class IV.

[The hygienic regulation of 3-phenoxybenzaldehyde in the atmosphere]. / Gigienicheskoe reglamentirovanie 3-fenoksibenzal'degida V atmosfernom vozdukhe.

The probable odour threshold of 3-phenoxybenzaldehyde (3-PBA) in the ambient air was estimated at 0.225 mg/m3. The maximum permissible concentration (MPC) of 3-PBA on a single exposure was recommended to be 0.09 mg/m3. The mean daily MPC of 3-PBA was proposed to be 0.03 mg/m3. The substance is regarded to fall in hazard class III.

[Rationale for maximum permissible concentration of kuscide in the air of the work area in agriculture]. / K obosnovaniiu predelno dopustimoi kontsentratsii kustsida v vozdukhe rabochei zony pri primenenii v selskom khoziaistve.

Inhalation exposure to kuscide changed the function of the CNS, microcirculation, blood cholinesterase activity. Kuscide concentration 40 mg/m3 is toxic for rats, 4 mg/m3 is threshold, and 0.4 mg/m3 is nonactual. MAC of kuscide for working environment is 0.5 mg/m3.