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J Cutan Pathol ; 48(5): 694-700, 2021 May.
Artículo en Inglés | MEDLINE | ID: mdl-33533041

RESUMEN

Lymphomatoid papulosis (LyP) type E is a rare variant of the primary cutaneous CD30+ lymphoproliferative disorders, characterized clinically by large necrotic eschar-like lesions and histopathologically by angiodestructive and angioinvasive infiltrates of CD30+ lymphocytes. As in other forms of lymphomatoid papulosis, type E lesions may undergo spontaneous regression after weeks, with frequent recurrences. We report a 21-year old male with an angiodestructive infiltrate of CD30+ lymphocytes manifesting as a papular eruption rather than ulceration, and suggest that this clinical phenotype might be related to the presence of CD4+ lymphocytes in the inflammatory cell infiltrate.


Asunto(s)
Vasos Sanguíneos/patología , Linfocitos T CD4-Positivos/metabolismo , Papulosis Linfomatoide/patología , Neoplasias Cutáneas/patología , Negro o Afroamericano/etnología , Diagnóstico Diferencial , Foliculitis/diagnóstico , Foliculitis/etiología , Humanos , Antígeno Ki-1/metabolismo , Perdida de Seguimiento , Ganglios Linfáticos/patología , Linfoma Anaplásico Cutáneo Primario de Células Grandes/diagnóstico , Linfoma Anaplásico Cutáneo Primario de Células Grandes/patología , Papulosis Linfomatoide/clasificación , Papulosis Linfomatoide/diagnóstico , Masculino , Persona de Mediana Edad , Fenotipo , Pronóstico , Adulto Joven
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