1.
EMBO Rep
; 22(1): e51227, 2021 01 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-33369847
RESUMEN
Biosafety is a major challenge for developing for synthetic organisms. An early focus on application and their context could assist with the design of appropriate genetic safeguards.
Asunto(s)
Contención de Riesgos Biológicos , Biología Sintética , Tecnología
2.
Trends Biotechnol
; 38(12): 1308-1312, 2020 12.
Artículo
en Inglés
| MEDLINE
| ID: mdl-32402415
RESUMEN
Safety-by-design (SbD) is paramount for risk management in synthetic biology, with genetic safeguards being a key technology for its implementation. While attractive in theory, the integration of genetic safeguards into SbD strategies is rarely exercised in practice, despite technological advances. Here we question why and what might be done about it.