Detalles de la búsqueda
1.
Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability.
Int J Mol Sci
; 25(1)2023 Dec 21.
Artículo
Inglés
| MEDLINE | ID: mdl-38203326
2.
Potential of Vitamin B6 Dioxime Analogues to Act as Cholinesterase Ligands.
Int J Mol Sci
; 23(21)2022 Nov 02.
Artículo
Inglés
| MEDLINE | ID: mdl-36362178
3.
Activation of (un)regulated cell death as a new perspective for bispyridinium and imidazolium oximes.
Arch Toxicol
; 95(8): 2737-2754, 2021 08.
Artículo
Inglés
| MEDLINE | ID: mdl-34173857
4.
Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers.
Arch Toxicol
; 94(9): 3157-3171, 2020 09.
Artículo
Inglés
| MEDLINE | ID: mdl-32583098
5.
Vitamin B3-Based Biologically Active Compounds as Inhibitors of Human Cholinesterases.
Int J Mol Sci
; 21(21)2020 Oct 29.
Artículo
Inglés
| MEDLINE | ID: mdl-33138280
6.
Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase.
Toxicol Appl Pharmacol
; 372: 40-46, 2019 06 01.
Artículo
Inglés
| MEDLINE | ID: mdl-30978400
7.
Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase.
Chemistry
; 25(16): 4100-4114, 2019 Mar 15.
Artículo
Inglés
| MEDLINE | ID: mdl-30458057
8.
Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration.
Chemistry
; 24(38): 9675-9691, 2018 Jul 05.
Artículo
Inglés
| MEDLINE | ID: mdl-29672968
9.
New Cinchona Oximes Evaluated as Reactivators of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Organophosphorus Compounds.
Molecules
; 22(7)2017 Jul 22.
Artículo
Inglés
| MEDLINE | ID: mdl-28737687
10.
A comprehensive evaluation of novel oximes in creation of butyrylcholinesterase-based nerve agent bioscavengers.
Toxicol Appl Pharmacol
; 310: 195-204, 2016 Nov 01.
Artículo
Inglés
| MEDLINE | ID: mdl-27654152
11.
Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes.
Chem Res Toxicol
; 28(5): 1036-44, 2015 May 18.
Artículo
Inglés
| MEDLINE | ID: mdl-25835984
12.
The PNPLA family of enzymes: characterisation and biological role.
Arh Hig Rada Toksikol
; 74(2): 75-89, 2023 Jun 01.
Artículo
Inglés
| MEDLINE | ID: mdl-37357879
13.
Insulin, dibutyryl-cAMP, and glucose modulate expression of patatin-like domain containing protein 7 in cultured human myotubes.
Front Endocrinol (Lausanne)
; 14: 1139303, 2023.
Artículo
Inglés
| MEDLINE | ID: mdl-37033214
14.
Selected herbicides screened for toxicity and analysed as inhibitors of both cholinesterases.
Chem Biol Interact
; 379: 110506, 2023 Jul 01.
Artículo
Inglés
| MEDLINE | ID: mdl-37141932
15.
The effects of ketamine on viability, primary DNA damage, and oxidative stress parameters in HepG2 and SH-SY5Y cells.
Arh Hig Rada Toksikol
; 74(2): 106-114, 2023 Jun 01.
Artículo
Inglés
| MEDLINE | ID: mdl-37357882
16.
Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells.
Toxicology
; 494: 153588, 2023 08 01.
Artículo
Inglés
| MEDLINE | ID: mdl-37419273
17.
New structural scaffolds for centrally acting oxime reactivators of phosphylated cholinesterases.
J Biol Chem
; 286(22): 19422-30, 2011 Jun 03.
Artículo
Inglés
| MEDLINE | ID: mdl-21464125
18.
Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in SH-SY5Y cells.
Arh Hig Rada Toksikol
; 73(4): 277-284, 2022 Dec 01.
Artículo
Inglés
| MEDLINE | ID: mdl-36607726
19.
PBDEs Found in House Dust Impact Human Lung Epithelial Cell Homeostasis.
Toxics
; 10(2)2022 Feb 19.
Artículo
Inglés
| MEDLINE | ID: mdl-35202283
20.
Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents.
Eur J Med Chem
; 238: 114377, 2022 Aug 05.
Artículo
Inglés
| MEDLINE | ID: mdl-35526478