RESUMEN
The distribution of the fluorescent euchrysine-binding grains in the peripheral and bonmarrow stem cells was estimated in 28 cases of different types of acute leukemia verified according to Lòffler's cytochemical classification. The relationship between the pattern of fluorescent euchrysine-binding grains of human stem cells and the cytochemical type of acute leukemias has been established. Consequently, the authors suggest that the euchrysine-binding grains pattern of human stem cells may have a diagnostic value in distinguishing between various types of acute leukemia.
Asunto(s)
Aminoacridinas , Células Madre Hematopoyéticas/patología , Leucemia/diagnóstico , Naranja de Acridina , Enfermedad Aguda , Adolescente , Médula Ósea/patología , Niño , Preescolar , Histocitoquímica , Humanos , Lactante , Leucemia/patología , Coloración y EtiquetadoRESUMEN
Clinical symptoms and haematological disorders in patients suffering from lymphoplasmatic/lymphoplasmocytoidal lymphoma were presented, 82 patients were examined (median age of 63), all of the in clinical stage IV (ANN Arbor scale). In all of the patients bone marrow was invaded. The most common symptom was enlargement of peripheral lymph nodes (86%) less often abdominal ones (21%). Splenomegalia was found in 55% and hepatomegalia in 49% of patients 35% of patients had anaemia and 38% thrombocytopenia. Close to 1/3 of patients dermatoses were found, in most cases allergic ones. In 7% another cancer was found.
Asunto(s)
Leucemia Linfocítica Crónica de Células B/diagnóstico , Adulto , Anciano , Anciano de 80 o más Años , Anemia/diagnóstico , Femenino , Humanos , Ganglios Linfáticos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Trombocitopenia/diagnósticoAsunto(s)
Inmunoglobulinas/análisis , Rinitis Atrófica/inmunología , Linfocitos T/inmunología , Adolescente , Adulto , Anciano , Niño , Femenino , Humanos , Masculino , Persona de Mediana Edad , Formación de RosetaAsunto(s)
Inmunoglobulinas/análisis , Rinitis Alérgica Estacional/inmunología , Linfocitos T/inmunología , Adulto , Desensibilización Inmunológica , Femenino , Humanos , Inmunoglobulina A/análisis , Inmunoglobulina G/análisis , Inmunoglobulina M/análisis , Masculino , Persona de Mediana Edad , Rinitis Alérgica Estacional/terapia , Formación de RosetaRESUMEN
Among 82 patients with L-LP in clinical stage IV, 14% were found to have monoclonal gammapathy and 22% polyclonal gammapathy. The other classes of immunoglobulins were not affected. In 78%, cell immunity was impaired. Decrease in T cell count (CD2+ and CD3+) in blood was found. Particularly T helper cells (CD4+), to a lesser degree T suppressor cells (CD8+) were affected. The life time of patients varied from 3 to 120 months. 60% of deaths were caused by infection.