RESUMEN
Three patients who were on the periphery of the pyroclastic flow of the Mount St. Helens eruption on May 18, 1980 were treated for severe thermal and inhalation injuries. Although exposed in identical manner, two patients arrived with heavily colonized burn wounds and developed adult respiratory distress syndrome leading directly to their death, whereas the third patient, with a noncolonized burn wound and little evidence of adult respiratory distress syndrome, survived. Evidence of inhaled ash complicating various stages of adult respiratory distress syndrome was confirmed by energy dispersive roentgenographic analysis. In the Pacific Northwest, Alaska, and the Aleutian Islands, potential for further injuries of this type in even larger numbers exists. Should these occur, those who treat the victims should be aware of the potential for severe inhalation problems in addition to the obvious burns.
Asunto(s)
Quemaduras por Inhalación/patología , Quemaduras/terapia , Desastres , Adulto , Contaminantes Atmosféricos/aislamiento & purificación , Humanos , Pulmón/patología , Masculino , OregonRESUMEN
The unusual occurrence of epidermoid carcinoma within an inclusion cyst arising on the forehead of a patient is documented. The importance of any irregular change or clinically abnormal behavior in such a lesion is underscored and the necessity for routine histological examination of all tissue excised is reaffirmed.
Asunto(s)
Carcinoma de Células Escamosas/etiología , Quiste Epidérmico/complicaciones , Neoplasias Cutáneas/patología , Carcinoma de Células Escamosas/patología , Carcinoma de Células Escamosas/cirugía , Quiste Epidérmico/cirugía , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Cutáneas/cirugíaRESUMEN
Pulmonary disease has been associated with several chemotherapeutic agents but has not been reported in patients receiving the alkylating agent mitomycin (Mutamycin). We describe here the cases of three patients who developed interstitial pneumonia while receiving mitomycin therapy. Their clinical features including dyspnea, cough, and occasionally fever; reticular infiltrates were seen on chest roentgenogram. Histologically, diffuse alveolar septal edema, mononuclear-cell interstitial infiltrates, hypertrophy of alveolar lining cells, and alveolar septal collagen deposition were characteristic. Treatment with corticosteroids was associated with a rapid therapeutic response in all three patients.