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1.
J Pharm Bioallied Sci ; 16(Suppl 1): S215-S218, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38595612

RESUMEN

Antidepressants have anti-inflammatory effects and boost immunity, and dentists should be aware. This case-control study included only those patients who consented to take part and had a ham-d score of at least 16 and a diagnosis of moderate-to-severe depression. Inclusion criteria included adults, those experiencing moderate to severe depression, taking fluoxetine or venlafaxine, and those with twenty or more teeth. Exclusion criteria included tobacco chewers, smokers, women expecting or nursing, periodontal treatment, antibiotics, anti-inflammatory medication, or vitamin/nutritional supplements. Patients who had had surgery or other therapy were excluded from the study. Three groups of patients were created: Control, venlafaxine, and fluoxetine. A periodontist assisted in the dental examination, and indices were observed. The analysis was done using Statistical Package for the Social Sciences (SPSS) version 24.0. Number, percentage, mean, and standard deviation were used to present the values. Results showed that antidepressants may be a risk factor for periodontal health, with increased periodontal parameters, and concluded that It is crucial to frequently check the periodontal health of depressed people using fluoxetine or venlafaxine since these drugs put good periodontal tissues at risk.

2.
J Pharm Bioallied Sci ; 15(Suppl 1): S187-S191, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37654361

RESUMEN

Introduction: Recurrent abutment substitutions may physically irritate the mucosal (soft tissue) barrier, which may cause additional toxic irritants and germs to enter the mucosal implant barrier and weaken the tissues surrounding implant. The creation of a "definitive abutment" may lessen the likelihood of tissue losses around the implant. Determining the characters of the peri-implant tissue after the placement of the definitive abutments and multiple abutment replacement was the goal of this study. Materials and Procedures: Forty missing teeth were replaced with implants in matched subjects. Parameters assessed were "distance of cement enamel junction to alveolar crest and distance of CEJ to gingival margin; bleeding on probing, Sulcus probing depth, and peri-implant marginal bone loss." Subjects were randomly assigned for the two groups of intervention. All the measurements were documented at designated timelines and compared for the statistical variance where P < 0.05 was considered as significant. Results: In the control and test groups, the peri-implant marginal bone level rose from baseline to 3 months. There were no appreciable differences between the CEJ-AC and CEJ-GM groups when the clinical and radiographic parameters of each group were evaluated. Throughout all of the time points, the soft tissue borders in both groups remained comparably steady. Conclusion: The study's findings suggest that using implants with definite abutments is more advantageous for obtaining better maintenance in terms of the health of the tissues that surround the implants.

3.
J Pharm Bioallied Sci ; 15(Suppl 1): S183-S186, 2023 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-37654403

RESUMEN

Introduction: In many oral procedures that involve the implants, hair implantations, "Platelet-Rich Fibrin Membrane (PRF)" is commonly applied. The advantages are many. In this study, the mechanical resistance of PRF under resistance pull on a longitudinal axis was assessed and compared. Material and Methods: For the current in vitro study, 60 volunteers donated each 10 ml of their blood and hence a total volume of 600 ml of blood was procured that was analyzed for the current study. The total volume was grouped to three groups where they receive three resistance centrifugation forces of "F-200,600,800 m/s²." In each group, 20 samples were tested for each level of the G-resistance. Each group was further divided as two subgroups of different times of wait, where they were centrifuged at baseline time and after a stand of 30 minutes. On universal testing equipment, the PRF membranes were mechanically tensioned in order to determine each membrane's resistance force. These values were compared for any statistical variance using appropriate statistical tools keeping P < 0.05. Results: Any applied force had no statistically significant effect on the centrifugation duration for membrane resistance. When the resistance was applied for the PRP samples immediately after they were procured, no significant variation was seen at all the grades of the centrifugation forces; consequently, the T30 group showed a statistically significant variance for the centrifugation forces applied (P = 0.04), with the highest value when the greatest force was applied. According to the results, the centrifugation waiting period could be determined based on the application requirement. Conclusion: For immediate membrane usage, the centrifugation had no effect on resistance; however, after 30 minutes, a membrane with greater resistance was produced by applying more force.

4.
J Pharm Bioallied Sci ; 14(Suppl 1): S280-S282, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36110623

RESUMEN

Introduction: The human body goes through a roller coaster of hormonal changes during pregnancy. The periodontal pathologies may alter and may bring about different/altered responses to normal stimuli. Hence, in our study, we assessed the relation between the chronic periodontitis and its impact on the intrauterine growth of the fetus. Material and Method: We conducted a retrospective observational study, where the data was collected from the institutional records. We included 200 pregnant subjects and grouped them equally as those with and without periodontal pathologies. We compared the groups for various parameters of the subject and the new born, and measured the significance deliberating P < 0.05 as significant. Results: We observed that among the various clinical parameters, the female subjects were exponentially prone to "vulvo-vaginitis, premature rupture of membranes" and the new born had restricted growth. Conclusion: Oral health affects the general health. The periodontal disease specifically has an adverse impact among pregnant women. Hence care should be given to oral hygiene maintenance.

5.
J Pharm Bioallied Sci ; 14(Suppl 1): S273-S274, 2022 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-36110599

RESUMEN

Introduction: Various materials are used to improve the longevity of the dental implants. In our study, we assessed the marginal bone loss around dental implants after implantation with platelet-rich plasma. Materials and Methods: We conducted a prospective clinical study among 200 subjects who were grouped equally as those with and without the application of PRF in the implantation. The radiographic and clinical features for the marginal bone loss were assessed and compared keeping P < 0.05 as statistically significant. Results: We observed no significant variation between the groups for the mobility, bleeding on probing, plaque index, and marginal bone loss. Conclusion: We can conclude that the application of PRP concentrate did not significantly affect the marginal bone loss in the dental implantation.

6.
J Pharm Bioallied Sci ; 13(Suppl 2): S1713-S1716, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-35018061

RESUMEN

BACKGROUND: Patients around the world when attending the dental clinic are prone to undergo the feelings of fear and anxiety. This may impact the dental follow-up and prognosis. AIM: The aim of the study is to evaluate the dental anxiety in the patients attending for the dental treatment in a college, in India. MATERIALS AND METHODS: A sample of 500 adults with ages 15-60 years was considered for the study. Modified dental anxiety questionnaire was used in the present study to assess the anxiety faced by the patients attending for the dental treatment. ANOVA and Chi-square test were used to test for the significance between the variables, and the correlation between these variables was assessed using the Spearman's correlation. Likert scale was used to know the cutoff for the severity of the dental anxiety. RESULTS: Only in the 4% of the participants in the present study had dental anxiety. Gender, age, financial status, education impacted the dental anxiety and the regularity toward the appointments. CONCLUSION: It can be concluded from our study that there was a low anxiety in the dental patients toward the dental treatment and also anxiety decreased with the age. However, regular dental visits are advised to prevent the overall impact of the oral health on the general health.

7.
J Pharm Bioallied Sci ; 13(Suppl 2): S1275-S1279, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-35017970

RESUMEN

BACKGROUND: Periodontitis is a chronic inflammatory disease with conglomerate etiology making it difficult to diagnose at the early stages. Potential biomarkers in gingival crevicular fluid (GCF) would determine the presence of the current disease activity, predict sites vulnerable for future breakdown, and assess the response to periodontal interventions. Merely elevated levels of inflammatory soft-tissue markers do not indicate bone destruction. Since there is no single ideal biomarker established, bone-related biomarkers such as telopeptide of type I collagen, osteocalcin, calprotectin, osteopontin, and tartrate-resistant acid phosphatase (TRAP) seem to hold great promise as predictive markers to determine bone destruction and active phases in the disease progression. The present study is intended to explore the biologic plausibility of the levels of TRAP in health and chronic periodontitis. MATERIALS AND METHODS: The present cross-sectional clinico-biochemical study comprised 30 systemically healthy subjects with 15 periodontally healthy and 15 chronic periodontitis subjects who were age and gender matched. GCF and blood samples were collected from all the patients. TRAP estimation was done in both the samples using an enzyme-linked immunosorbent assay kit. The data were analyzed using independent t-test and Pearson correlation test. RESULTS: Serum and GCF TRAP levels in chronic periodontitis subjects were significantly higher when compared to the periodontally healthy group. There were no significant correlations found among serum and GCF TRAP levels with increasing age and gender in both the groups. An increase in disease severity, i.e., increase in probing pocket depth and clinical attachment level, did not show correlation with the GCF and serum TRAP levels in the chronic periodontitis group. CONCLUSION: Based on the findings of the present study, increased GCF TRAP levels in chronic periodontitis seem to be a potential marker for identifying ongoing periodontal destruction.

8.
J Oral Maxillofac Pathol ; 25(1): 189-192, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34349434

RESUMEN

BACKGROUND: To emphasize the role of odontometric parameters which may be used as a reliable forensic tool especially in cases with partial remains of the individual. AIM: To assess the reliability of odontometric parameters in stature analysis. MATERIALS AND METHODS: The study was conducted on 100 patients (50 male and 50 Female). Mesiodistal width of anterior teeth, inter-canine width, Inter-premolar width and maxillary arch length were the parameters included. The results were tabulated with a linear regression formula obtained for each parameter. STATISTICAL ANALYSIS: The data collected was statistically analysed using SPSS version 20 and a linear regression formula was obtained thereafter. RESULTS: Mesio-distal widths of individual maxillary canines, total mesiodistal width of maxillary anteriors and arch length showed a significant co-relation with stature. The combined linear regression formula was obtained for all parameters. CONCLUSION: Odontometric parameters of mesio - distal widths of individual maxillary canines, total mesiodistal width of maxillary anteriors and arch length can be used as reliable parameters for stature analysis.

9.
Indian J Dent Res ; 25(4): 541-3, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-25307925

RESUMEN

OBJECTIVES: The purpose of this paper is to develop a simple and cost-effective suturing training model. MATERIALS AND METHODS: A simplified suturing model is developed for preclinical training purpose. The training model requires only three easily available materials, which include synthetic foam sponge, elastomeric impression material and putty impression material. Construction of this model requires only 15 min. RESULTS: The training model thus developed resembles a realistic human tissue with a skin analog, deeper connective tissues and a bony base. This enables the students to practice various suturing technique at different tissue planes. Such practice helps the students to perform a live procedure in a more skilled and less traumatic way. CONCLUSION: The easy availability and cost-effective nature of the materials, in concert with fast construction time, makes this suturing model appropriate when an affordable alternative is desired.


Asunto(s)
Modelos Biológicos , Suturas , Humanos
10.
J Indian Soc Periodontol ; 16(4): 553-7, 2012 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-23493496

RESUMEN

AIMS AND OBJECTIVES: The aim of this study is to evaluate the effectiveness of a controlled-release chlorhexidine chip as an adjunctive therapy to scaling and root planing when compared with scaling and root planing alone in the treatment of chronic periodontitis. MATERIALS AND METHODS: 20 patients with a total number of 40 posterior sites were selected. These sites were divided into two groups in a split mouth design,: Group A (control site) had 20 sites treated with scaling and root planing alone and Group B (test site) had 20 sites treated with scaling and root planing and PerioCol™-CG. The clinical parameters (Plaque index, bleeding on probing, probing pocket depth, clinical attachment level) were recorded at baseline, 90(th) and 180(th) day for both the groups. RESULTS: When both groups were compared the change in Plaque index was significantly higher in Group B when compared to Group A on the 90(th) day and 180(th) day. However, there was no statistically significant difference in the mean percentage of gingival bleeding sites between the two groups on the 90(th) day, though Group B showed a statistically higher reduction in the mean percentage of gingival bleeding sites at the end of 180(th) day. There was no statistically significant difference in probing pocket depth between the two groups on both 90(th) and 180(th) day. Gain in clinical attachment level was significantly higher in Group B when compared to Group A on the 90(th) and 180(th) day. CONCLUSION: From the results observed in this study, it can be concluded that the adjunctive use of PerioCol™-CG was safe and provided significant improvement in both Plaque index and gingival bleeding index. It was also more favorable than scaling and root planing alone for gain in clinical attachment level.

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