1.
Org Lett
; 22(11): 4389-4394, 2020 06 05.
Artículo
en Inglés
| MEDLINE
| ID: mdl-32459499
RESUMEN
A method to activate sulfamoyl fluorides, fluorosulfates, and sulfonyl fluorides with calcium triflimide and DABCO for SuFEx with amines is described. The reaction was applied to a diverse set of sulfamides, sulfamates, and sulfonamides at room temperature under mild conditions. Additionally, we highlight this transformation to parallel medicinal chemistry to generate a broad array of nitrogen-based S(VI) compounds.
2.
Org Lett
; 20(13): 3943-3947, 2018 07 06.
Artículo
en Inglés
| MEDLINE
| ID: mdl-29888600
RESUMEN
A method using calcium triflimide [Ca(NTf2)2] as a Lewis acid to activate sulfonyl fluorides toward nucleophilic addition with amines is described. The reaction converts a wide array of sterically and electronically diverse sulfonyl fluorides and amines into the corresponding sulfonamides in good yield.