RESUMEN
An experimental model of acute and chronic ethanol poisoning is described. Electrocardiographic and morphologic changes in the hearts of white rats, exposed to alcoholic intoxication, have been assessed. Typical ECG features as well as muscle-cell and neuron ultrastructure have been identified, so that they could be used for morphologic and functional assessment of alcoholic poisoning.
Asunto(s)
Intoxicación Alcohólica/patología , Sistema de Conducción Cardíaco/fisiopatología , Miocardio/patología , Intoxicación Alcohólica/fisiopatología , Animales , Atrios Cardíacos/fisiopatología , Ventrículos Cardíacos/fisiopatología , Masculino , Microscopía Electrónica , Miocardio/ultraestructura , Ratas , Ratas EndogámicasRESUMEN
A study of the cavitary and membrane digestion of lipids, carbohydrates, proteins and data of the histological structure of the bioptate of the duodenal mucosa in 34 patients with chronic pancreatitis revealed the morphological picture of chronic duodenitis. This resulted in a reduction of the sorption properties of the intestinal epithelium that was manifested in a reduction of the rate of membranous digestion, mainly of lipids and lactose. Lesser degrees of protein, starch and saccharose hydrolysis were observed. Biopsy specimens of the duodenal mucosa showed a reduced activity of enterokinase and alkaline phosphatase. Antacids (almagel, phosphalugel), mineral waters ("Borzhomi", "Poliana Kvasova"), regeneration stimulators (Metacyl, retalil), agents stimulating the motor function (cerukal, reglan and oth.) are recommended for the complex treatment of concomitant duodenitis.