Clinically therapeutic study of intramuscular ketoprofen in rheumatic diseases.

We have studied the effect of ketoprofen (19583 R.P.) given intramuscularly in some painful rheumatic conditions, notably root pains of disc and spinal origin and inflammatory conditions, and it has proved to be an effective analgesic and anti-inflammatory product, and in our series of 30 patients was very well tolerated.

[Generalised cortical hyperostosis. One case (author's transl)]. / Hyperostose corticale généralisée. Une observation.

Generalised cortical hyperostosis, a case of which is reported here, was distinguished from other condensing osteopathies by Van Buchem in 1955. It is characterised by a fairly special facial dysmorphia, associated with osteocondensation of the skull, spine, flat bones and the cortex of the long bones of the limbs. There is a form with recessive transmission, which is usually associated with cranial nerve involvement by compression, and alkaline hyperphosphatasemia, whilst in the form with dominant transmission these abnormalities are not usually present. By contrast, there is often a palatal torus. A case appeared to share features of both forms. The prognosis is usually favourable, in contrast to that of osteopetrosis, a condition with which it is often confused.

[Injection of the sacrolumbar roots: a complementary method of staging sciatica. 18 cases]. / Injection des racines lombaires et sacrées. Une méthode complémentaire pour préciser l'étage d'une sciatique. A propos de 18 cas.

The injection of the sacrolumbar roots allows, in the first place, the root to be made opaque in order to determine its morphology and, in the second place and above all, causes the disappearance of the radicular pain after injection of a local anesthetic, which helps the degree of sciatica to be identified. This method, which should be limited to exceptional cases, seems to be useful in patients who have undergone lumbar surgery and for whom the interpretation of contrast x-ray exams poses a particularly delicate problem. It can also be advisable when these exams are not conclusive or when the results do not coincide with the clinical data. Since March, 1974, 18 patients have undergone this exam. In 14 cases the disappearance of the radicular syndrome, after injection of xylocain close to the root, has allowed the root in question to be identified. In 3 cases radicular injection has practically made it possible to rule out an organic lesion. This exam had no side effect and was always tolerated even by two patients allergic to iodine.