RESUMEN
More than ten years have eLapsed since highly active antiretroviral therapy [HAART] was introduced to treat people living with HIV. Unfortunately, there is still no light at the end of the road leading to complete eradication of the virus and full recovery, or to the development of immunization that will be safe and effective in the long run. Nevertheless, in recent years with the introduction of more effective and safer drugs, that also have a high genetic barrier, and a more comfortable pharmacological profile and better tolerance, HIV has become a manageable chronic disease and patients can live many years with a good quality of life. These developments have significantly influenced epidemiological, therapeutic, psychological and social aspects of the AIDS epidemic.