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Zhong Yao Cai ; 34(11): 1709-11, 2011 Nov.
Artículo en Zh | MEDLINE | ID: mdl-22506393

RESUMEN

OBJECTIVE: To research the chemical constituents from the aerial parts of Medicago sativa. METHODS: Various column chromatographies were emoployed to isolate and purify the constituents. Their structures were elucidated by spectral analysis (IR, UV, MS, 1H-NMR, 13C-NMR) and chemical evidence. RESULTS: Two constituents were obtained and identified as soysaponin I (I), azukisaponin V (II). CONCLUSION: These two compounds are isolated from the arial parts of Mesicago sativa for the first time. Moreover,the compounds are found to have hypolipidemic activity.


Asunto(s)
Hipolipemiantes/farmacología , Medicago sativa/química , Componentes Aéreos de las Plantas/química , Saponinas/aislamiento & purificación , Saponinas/farmacología , Animales , Colesterol/sangre , Modelos Animales de Enfermedad , Hiperlipidemias/sangre , Hiperlipidemias/tratamiento farmacológico , Hipolipemiantes/aislamiento & purificación , Masculino , Ratones , Estructura Molecular , Saponinas/química , Espectrofotometría Ultravioleta
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