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1.
J S Afr Vet Assoc ; 82(4): 242-3, 2011 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-22616440

RESUMEN

A 7-year-old female beagle was evaluated for symptomatic hypercalcaemia and primary hypothyroidism. Clinical findings were typical for hypothyroidism. Plasma parathyroid hormone was low and obvious causes for the hypercalcaemia were ruled out by means of abdominal ultrasonography, ultrasonography of the parathyroid glands, survey thoracic radiographs, and fine needle aspirate cytology of the spleen, liver, and peripheral lymph nodes. Treatment with thyroxine resulted in resolution of the hypercalcaemia after approximately 9 weeks of therapy. This is the 1st report of primary adult-onset hypothyroidism associated with symptomatic hypercalcaemia in a dog.


Asunto(s)
Enfermedades de los Perros/diagnóstico , Hipercalcemia/veterinaria , Hipotiroidismo/veterinaria , Tiroxina/uso terapéutico , Animales , Enfermedades de los Perros/tratamiento farmacológico , Perros , Femenino , Hipercalcemia/diagnóstico , Hipercalcemia/tratamiento farmacológico , Hipercalcemia/etiología , Hipotiroidismo/complicaciones , Hipotiroidismo/diagnóstico , Hipotiroidismo/tratamiento farmacológico , Resultado del Tratamiento
2.
Vet Med Int ; 2020: 4106435, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32148748

RESUMEN

The purpose of this study was to investigate in healthy adult dogs if there was a daily fluctuation in the FCNa, the role that dietary sodium intake played on the FCNa, and the role that feeding played on the obtained value for FCNa. Three different diets were used in a group of 8 healthy beagle dogs in a crossover design. The sodium content of the diets was normal (0.26%), low (0.18%), and ultralow (0.06%). Spot urine and blood samples were collected from which the urine and serum sodium and creatinine concentration were determined, and the FCNa was calculated. The median FCNa for the normal, low, and ultralow sodium diets was 0.5, 0.77, and 0.15, respectively. Individual dogs showed a daily variation in FCNa, and samples which were collected shortly after eating showed the greatest variation. This study showed that in a group of healthy beagle dogs without obvious renal disease, the FCNa could exceed 1 and that there was both an individual and daily variation in the FCNa. The greatest variation was seen whilst the dogs were fed the low and ultralow sodium diets and when the samples were collected shortly after eating. This study concluded that an FCNa > 1% may not be indicative of acute tubular dysfunction in young dogs, and use of the FCNa for assessing renal function in clinical cases should take into account the animal's diet, as well as the time the samples were taken in relation to feeding.

3.
J S Afr Vet Assoc ; 80(2): 103-5, 2009 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-19831272

RESUMEN

Over a period of approximately 1 year, 2 sibling Rottweilers and their dam in the same household developed stage IV and stage III lymphoma, respectively. All 3 initially responded to doxorubicin chemotherapy but relapsed after approximately 3 months and were subsequently euthanased. As no obvious environmental trigger could be identified in these dogs, it is speculated that an underlying genetic predisposition could have played a role in the development of lymphoma in these related dogs.


Asunto(s)
Antibióticos Antineoplásicos/uso terapéutico , Enfermedades de los Perros/genética , Doxorrubicina/uso terapéutico , Linfoma/veterinaria , Animales , Enfermedades de los Perros/tratamiento farmacológico , Perros , Resultado Fatal , Femenino , Predisposición Genética a la Enfermedad , Linfoma/tratamiento farmacológico , Linfoma/genética , Linaje
4.
J S Afr Vet Assoc ; 80(2): 106-7, 2009 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-19831273

RESUMEN

A 4-month-old male Jack Russell terrier was evaluated for non-painful muscle spasms and collapse associated with exercise and activity. Clinical examination revealed well-defined, non-painful hypertrophic muscles of the fore and hind limbs and exercise and excitement induced hindquarter bunny-hopping gait, which improved with activity but worsened with resting and with any sudden changes in direction of movement. Neurological examination and routine laboratory testing showed no abnormalities. DNA analysis for myotonia congenita showed the dog to have a gene mutation in the chloride ion channel, diagnostic for myotonia congenita, which has not been reported in the Jack Russell terrier breed.


Asunto(s)
Canales de Cloruro/genética , Enfermedades de los Perros/genética , Músculo Esquelético/metabolismo , Miotonía Congénita/veterinaria , Animales , Enfermedades de los Perros/diagnóstico , Perros , Predisposición Genética a la Enfermedad , Masculino , Mutación , Miotonía Congénita/diagnóstico , Miotonía Congénita/genética
5.
J S Afr Vet Assoc ; 80(4): 224-8, 2009 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-20458862

RESUMEN

Chronic nasal disease is a common problem in dogs. To determine the aetiology, a retrospective study in 75 dogs with persistent and chronic nasal disease was done. All dogs were evaluated by means of survey nasal radiographs, antegrade and retrograde rhinoscopy, bacterial and fungal cultures, and histopathology. A definitive diagnosis was made in 74/75 cases (98.6%). Nasal neoplasia was the most common diagnosis (46.7%), median age 108 months, followed by lympho-plasmacytic rhinitis (20%), median age 112 months, and fungal rhinitis (10.7%), median age 53.5 months. Other diagnoses included nasal foreign body (5.3%), median age 51 months, and primary bacterial rhinitis (6.7%), median age 116.5 months. Rare aetiologies identified were nasal polyps, granulomatous rhinitis, oro-nasal fistula and naso-pharyngeal stenosis. This study showed that by using a structured combination of survey radiography, rhinoscopy, cultures and histopathology, a diagnosis could be made in dogs with chronic nasal disease.


Asunto(s)
Enfermedades de los Perros/diagnóstico , Enfermedades de los Perros/etiología , Cavidad Nasal/patología , Enfermedades Nasales/veterinaria , Factores de Edad , Animales , Enfermedad Crónica , Diagnóstico Diferencial , Enfermedades de los Perros/epidemiología , Perros , Femenino , Cuerpos Extraños/diagnóstico , Cuerpos Extraños/epidemiología , Cuerpos Extraños/etiología , Cuerpos Extraños/veterinaria , Masculino , Cavidad Nasal/microbiología , Pólipos Nasales/diagnóstico , Pólipos Nasales/epidemiología , Pólipos Nasales/etiología , Pólipos Nasales/veterinaria , Enfermedades Nasales/diagnóstico , Enfermedades Nasales/epidemiología , Enfermedades Nasales/etiología , Neoplasias Nasales/diagnóstico , Neoplasias Nasales/epidemiología , Neoplasias Nasales/etiología , Neoplasias Nasales/veterinaria , Estudios Retrospectivos , Rinitis/diagnóstico , Rinitis/epidemiología , Rinitis/etiología , Rinitis/veterinaria , Sudáfrica/epidemiología
6.
J S Afr Vet Assoc ; 78(3): 175-7, 2007 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-18237044

RESUMEN

A 9-year-old male cat was presented for evaluation of chronic weight loss and was subsequently diagnosed with pericardial effusion. The effusion was quantified as a septic exudate caused by the anaerobic bacterium Peptostreptococcus. Antibiotic therapy resulted in complete resolution of the pericardial effusion. As Peptostreptococcus is a common oral bacterium and the cat had a previous dental procedure, it is speculated that the pericardial effusion was secondary to bacteraemia from the dental procedure.


Asunto(s)
Enfermedades de los Gatos/diagnóstico , Atención Odontológica/veterinaria , Infecciones por Bacterias Grampositivas/veterinaria , Peptostreptococcus/aislamiento & purificación , Derrame Pericárdico/veterinaria , Animales , Antibacterianos/uso terapéutico , Enfermedades de los Gatos/etiología , Gatos , Atención Odontológica/efectos adversos , Infecciones por Bacterias Grampositivas/diagnóstico , Infecciones por Bacterias Grampositivas/etiología , Masculino , Derrame Pericárdico/diagnóstico , Derrame Pericárdico/etiología , Resultado del Tratamiento
7.
J S Afr Vet Assoc ; 77(3): 150-4, 2006 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-17137057

RESUMEN

Canine osteosarcoma is the most commonly diagnosed primary bone tumour in the dog, affecting mainly large and giant breed dogs with the predilection site being the metaphysis of long bones, specifically the distal radius, proximal humerus, distal femur and proximal tibia and fibula. Treatment options are either palliative or curative intent therapy, the latter limb amputation or limb-sparing surgery together with chemotherapy. This article describes the use of an ipsilateral vascularised ulnar transposition autograft as well as chemotherapy in 2 dogs with osteosarcoma of the distal radius. Both dogs showed minimal complications with the technique and both survived over 381 days following the surgery. Complications seen were loosening of the screws and osteomyelitis. The procedure was well tolerated with excellent limb use. This technique is indicated for use in cases with small tumour size that have not broken through the bone cortex.


Asunto(s)
Neoplasias Óseas/veterinaria , Trasplante Óseo/veterinaria , Enfermedades de los Perros/cirugía , Osteosarcoma/veterinaria , Radio (Anatomía)/trasplante , Cúbito/trasplante , Animales , Antineoplásicos/uso terapéutico , Neoplasias Óseas/tratamiento farmacológico , Neoplasias Óseas/cirugía , Terapia Combinada/veterinaria , Enfermedades de los Perros/tratamiento farmacológico , Perros , Masculino , Osteosarcoma/tratamiento farmacológico , Osteosarcoma/cirugía , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/veterinaria , Radio (Anatomía)/irrigación sanguínea , Radio (Anatomía)/cirugía , Flujo Sanguíneo Regional , Resultado del Tratamiento , Cúbito/irrigación sanguínea , Cúbito/cirugía
8.
J S Afr Vet Assoc ; 77(1): 40-1, 2006 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-16700475

RESUMEN

Nephro-cutaneous fistula, although reported in humans, has not been reported in the dog. In humans the majority of cases develop in patients with a history of previous renal surgery, renal trauma, renal tumours, or chronic urinary tract infection with abscess formation. The dog in this report developed a nephro-cutaneous fistula secondary to a traumatic induced renal abscess with formation of a draining sinus tract to the exterior of the body. The animal underwent simple nephrectomy, which resulted in complete resolution of the fistula.


Asunto(s)
Fístula Cutánea/veterinaria , Enfermedades de los Perros/cirugía , Enfermedades Renales/veterinaria , Enfermedades de la Piel/veterinaria , Animales , Fístula Cutánea/etiología , Fístula Cutánea/cirugía , Enfermedades de los Perros/etiología , Perros , Enfermedades Renales/complicaciones , Enfermedades Renales/cirugía , Masculino , Piel/patología , Enfermedades de la Piel/etiología , Enfermedades de la Piel/cirugía , Resultado del Tratamiento
9.
J S Afr Vet Assoc ; 77(4): 175-8, 2006 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-17458340

RESUMEN

Pigmented serum, usually due to free haemoglobin and/or bilirubin, is a common finding in dogs with babesiosis, resulting in interference with all biochemical tests that rely on photochemistry. This is particularly true of urea and creatinine determinations, complicating the diagnosis of acute renal failure, which is a serious complication of babesiosis. A disproportionately raised serum urea concentration of unknown origin occurs in severely anaemic canine babesiosis patients and gives rise to an increased serum urea:creatinine ratio. The assay for cystatin-C, an excellent measure of glomerular filtration rate, is unaffected by free serum haemoglobin, and due to its different intrinsic origins, is free of influence by the metabolic derangements and organ pathology, other than renal disease, encountered in canine babesiosis. Serum cystatin-C was used to compare the concentrations of serum urea and serum creatinine in dogs with the severely anaemic form of canine babesiosis as well as a canine babesiosis-free reference group. Mean serum urea and mean serum urea:creatinine ratio were significantly elevated in the babesia-infected group relative to the reference population in this study. Mean serum creatinine and mean serum cystatin-C were within the reference ranges. Therefore an elevated urea:creatinine ratio in canine babesiosis in the presence of a normal serum creatinine concentration is considered to be caused by an elevated serum urea concentration and is most likely of non-renal origin. Serum creatinine was therefore as specific a measure of renal function as serum cystatin-C in canine babesiosis in this study. The sensitivity of serum creatinine as a measure of renal function was not established by this study. Serum urea, however, proved to be of little use compared to serum cystatin-C and serum creatinine. Serum urea should therefore not be used to diagnose renal failure in canine babesiosis.


Asunto(s)
Babesiosis/veterinaria , Creatinina/sangre , Enfermedades de los Perros/sangre , Urea/sangre , Animales , Babesiosis/sangre , Babesiosis/complicaciones , Babesiosis/diagnóstico , Estudios de Casos y Controles , Cistatina C , Cistatinas/sangre , Diagnóstico Diferencial , Enfermedades de los Perros/diagnóstico , Perros , Enfermedades Renales/diagnóstico , Enfermedades Renales/etiología , Enfermedades Renales/veterinaria , Estudios Prospectivos , Valores de Referencia
10.
J S Afr Vet Assoc ; 76(1): 4-8, 2005 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-15900893

RESUMEN

Cardiac dysfunction in canine babesiosis has traditionally been regarded as a rare complication, with the majority of lesions reported as incidental findings at post-mortem examination. Recent studies have, however, demonstrated cardiac lesions in canine babesiosis. Cardiac troponins, especially troponin I, are sensitive markers of myocardial injury in canine babesiosis, and the magnitude of elevation of plasma troponin I concentrations appears to be proportional to the severity of the disease. ECG changes in babesiosis are similar to the pattern described for myocarditis and myocardial ischaemia and together with histopathological findings indicate that the heart suffers from the same pathological processes described in other organs in canine babesiosis, namely inflammation and hypoxia. The clinical application of the ECG appears to be limited and thus cardiovascular assessment should be based on functional monitoring rather than an ECG tracing. On cardiac histopathology from dogs that succumbed to babesiosis, haemorrhage, necrosis, inflammation and fibrin microthrombi in the myocardium were documented, all of which would have resulted in ECG changes and elevations in cardiac troponin. Myocardial damage causes left ventricular failure, which will result in hypotension and an expansion of the plasma volume due to homeostatic mechanisms.


Asunto(s)
Babesiosis/veterinaria , Enfermedades de los Perros/patología , Cardiopatías/veterinaria , Troponina I/sangre , Animales , Babesiosis/complicaciones , Babesiosis/patología , Enfermedades de los Perros/sangre , Enfermedades de los Perros/parasitología , Perros , Electrocardiografía , Cardiopatías/sangre , Cardiopatías/parasitología , Cardiopatías/patología , Índice de Severidad de la Enfermedad
11.
J S Afr Vet Assoc ; 76(3): 146-50, 2005 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-16300182

RESUMEN

The pharmacokinetics of diminazene aceturate following intramuscular (i.m.) administration at 4.2 mg/kg was evaluated in 8 healthy German Shepherd dogs. Blood samples were collected at 19 intervals over a period of 21 days. Diminazene plasma concentrations were measured using a validated HPLC method with UV detection and a sensitivity of 25 ng/ml. The in vitro and in vivo binding of diminazene to blood elements was additionally determined. Diminazene pharmacokinetics showed a large inter-individual variation after i.m. administration. It had a short absorption half-life (K01-HL of 0.11 +/- 0.18 h), resulting in a C(max) of 1849 +/- 268.7 ng/ml at T(max) of 0.37 h and a mean overall elimination half-life (T1/2beta) of 5.31 +/- 3.89 h. A terminal half-life of 27.5 +/- 25.0 h was measured. At 1 h after i.m. injection, 75% of the diminazene in whole blood was in the plasma fraction. The results of this study indicate that diminazene is rapidly distributed and sequestered into the liver, followed by a slower terminal phase during which diminazene is both redistributed to the peripheral tissues and/or renally excreted. It is recommended that diminazene administered i.m. at 4.2 mg/kg should not be repeated within a 21-day period.


Asunto(s)
Diminazeno/farmacocinética , Perros/metabolismo , Tripanocidas/farmacocinética , Absorción , Animales , Cromatografía Líquida de Alta Presión/métodos , Cromatografía Líquida de Alta Presión/veterinaria , Diminazeno/sangre , Semivida , Inyecciones Intramusculares/veterinaria , Riñón/metabolismo , Hígado/metabolismo , Masculino , Distribución Tisular , Tripanocidas/sangre
12.
Am J Vet Res ; 61(12): 1501-7, 2000 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-11131588

RESUMEN

OBJECTIVES: To investigate renal function in clinically normal dogs undergoing general anesthesia for ovariohysterectomies that received nonsteriodal antiinflammatory drugs (NSAID) before surgery. ANIMALS: 40 clinically normal dogs. PROCEDURE: After induction of anesthesia, dogs were given an analgesic. Renal function was assessed before surgery and 24 and 48 hours after surgery by means of serum urea and creatinine concentrations, fractional clearance of sodium (FC(Na)), urine gamma-glutamyltransferase (GGT) and alkaline phosphatase (ALP) activities, and urine analysis. Ten dogs in each of 4 groups received ketorolac tromethamine (0.5 mg/kg of body weight), ketoprofen (1 mg/kg), carprofen (4 mg/kg), or morphine (0.1 mg/kg; control group). RESULTS: Duration of general anesthesia ranged from 1.75 to 5 hours, with a mean of 3 hours. Two ketorolac- and 2 ketoprofen-treated dogs had transient azotemia. A significant decrease in the FC(Na) between before surgery and 24 hours after surgery, and between before surgery and 48 hours after surgery, was found in ketoprofen- and carprofen-treated dogs. Ketorolac-, ketoprofen-, and morphine-treated dogs had a decrease in urine specific gravity. Two ketorolac, 1 ketoprofen-, 1 carprofen-, and 4 morphine-treated dogs had increases in renal tubular epithelial cells on urine sediment examination 24 hours after surgery. CONCLUSIONS AND CLINICAL RELEVANCE: In clinically normal dogs undergoing general anesthesia and elective surgery, the use of NSAID as analgesics is not contraindicated. Compared with ketorolac or ketoprofen, carprofen had the least effect on renal function and integrity.


Asunto(s)
Antiinflamatorios no Esteroideos/farmacología , Histerectomía/veterinaria , Riñón/fisiología , Ovariectomía/veterinaria , Fosfatasa Alcalina/orina , Animales , Creatinina/sangre , Perros , Femenino , Riñón/efectos de los fármacos , Pruebas de Función Renal/veterinaria , Periodo Posoperatorio , Valores de Referencia , Sodio/metabolismo , Urea/sangre , gamma-Glutamiltransferasa/orina
13.
Vet Rec ; 150(6): 171-6, 2002 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-11888110

RESUMEN

Lead II electrocardiograms (ECGs) were recorded in 88 dogs ranging in weight from 3 to 50 kg. A commercial direct-writing electrocardiograph was used to record the ECGs, first with manual HUM filter (notch filter at 50/60 Hz) and EMG filter (cut-off frequency of -3 dB at 35 Hz) on, immediately followed by a recording with both filters off. The mean (sd) reduction in R-amplitude with the filters on was 53(18) per cent with a range from 22 to 100 per cent and a median value of 51 per cent. The R-amplitude with the filters off was related to the R-amplitude with the filters on, making it possible to correct for the effect of the filters. The reduction in R-amplitude was inversely correlated with the weight of the dog and with the duration of the QRS-complex. Other known changes induced by filters, such as the elimination of notches and the slurring of the junction between the QRS-complex and the ST-interval were also observed. The inverse relationship between the weight of the dog and the magnitude of the reduction in R-amplitude by the filters indicates that ECG machines with different characteristics should ideally be used to record ECGs in dogs of different sizes.


Asunto(s)
Electrocardiografía/instrumentación , Animales , Perros , Diseño de Equipo , Femenino , Masculino
14.
J Small Anim Pract ; 37(6): 286-91, 1996 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-8965483

RESUMEN

Rhabdomyolysis was diagnosed in two dogs with babesiosis. The first animal presented with muscle pain and caramel-coloured urine, and had markedly elevated serum myoglobin and muscle enzymes. Acute renal failure complicated the clinical picture. The second dog exhibited muscle pain and tremors, together with neurological signs and pulmonary oedema, and died soon after admission. Muscle necrosis and haemorrhage were found at necropsy. In human malaria, a disease clinically similar to canine babesiosis, rhabdomyolysis is unusual, but clinically silent muscle damage appears to be common. Likewise, biochemical evidence of muscle damage is readily found in experimental bovine babesiosis. Muscle enzymes were mildly elevated in three dogs with severe babesiosis and pigmenturia but there was no obvious muscle damage, indicating that this might also apply to canine babesiosis. The pathogenesis of infection-associated rhabdomyolysis and acute renal failure remains unclear, but inflammatory cytokines and nitric oxide could play an important role.


Asunto(s)
Babesiosis/complicaciones , Enfermedades de los Perros/etiología , Rabdomiólisis/veterinaria , Animales , Babesiosis/parasitología , Babesiosis/orina , Enfermedades de los Perros/parasitología , Enfermedades de los Perros/orina , Perros , Masculino , Rabdomiólisis/etiología
15.
J Small Anim Pract ; 39(3): 144-7, 1998 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-9551384

RESUMEN

A 14-month-old, male German shepherd dog was evaluated for chronic, recurrent Escherichia coli urinary tract infection. An initial diagnosis of emphysematous cystitis was made, which resolved with appropriate antibacterial therapy. The urinary tract infection, however, did not resolve and on further investigation a bladder trigone diverticulum was evident, thought to be congenital in origin. This report describes the apparent ultrasonographic and radiological changes, and surgical repair of the diverticulum, and reviews the literature with regard to both congenital bladder trigone diverticulum and emphysematous cystitis. The former has never been documented in the dog and the latter is an unusual finding in a non-diabetic dog.


Asunto(s)
Cistitis/veterinaria , Divertículo/veterinaria , Enfermedades de los Perros/diagnóstico por imagen , Enfermedades de la Vejiga Urinaria/veterinaria , Combinación Amoxicilina-Clavulanato de Potasio/uso terapéutico , Animales , Antibacterianos/uso terapéutico , Cistitis/tratamiento farmacológico , Divertículo/diagnóstico por imagen , Divertículo/cirugía , Enfermedades de los Perros/cirugía , Perros , Masculino , Ultrasonografía , Enfermedades de la Vejiga Urinaria/diagnóstico por imagen , Enfermedades de la Vejiga Urinaria/cirugía
16.
J Small Anim Pract ; 37(11): 552-5, 1996 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-8934429

RESUMEN

A six-month-old Rhodesian ridgeback dog was presented for evaluation of facial swelling. Chronic renal failure was clinically diagnosed based on urinalysis, biochemical changes and ultrasonography. The facial swelling was due to fibrous osteodystrophy, which was evident on survey radiographs of the skull. On post mortem examination, chronic renal failure as a result of renal dysplasia was confirmed. This is the first reported case of renal dysplasia in this breed of dog.


Asunto(s)
Enfermedades de los Perros/diagnóstico , Enfermedades Renales/veterinaria , Animales , Cruzamiento , Diagnóstico Diferencial , Enfermedades de los Perros/etiología , Enfermedades de los Perros/genética , Perros , Riñón/diagnóstico por imagen , Riñón/patología , Enfermedades Renales/complicaciones , Enfermedades Renales/diagnóstico , Fallo Renal Crónico/etiología , Fallo Renal Crónico/veterinaria , Masculino , Radiografía , Cráneo/diagnóstico por imagen , Cráneo/patología , Ultrasonografía
17.
J Small Anim Pract ; 44(8): 359-62, 2003 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-12934810

RESUMEN

A one-year-old, male, smooth-haired standard dachshund was presented with a history of chronic hypersalivation, dysphagia, puffing of the cheeks on expiration, and inspiratory stridor. Oral examination revealed a moderately thickened tongue radix and that the normal intrapharyngeal opening was obliterated. A 7 mm long, midline palatal slit was the only communication between the naso- and oropharynx. The soft palate was fused to the caudal pharyngeal wall. A concurrent hiatal hernia was diagnosed on thoracic radiographs. The soft palate abnormality was surgically corrected and the hiatal hernia was managed medically. On follow-up evaluations, the clinical signs had markedly improved, and the hiatal hernia was no longer visible on survey thoracic radiographs.


Asunto(s)
Enfermedades de los Perros/congénito , Hernia Hiatal/veterinaria , Paladar Blando/anomalías , Faringe/anomalías , Procedimientos de Cirugía Plástica/veterinaria , Animales , Perros , Hernia Hiatal/congénito , Hernia Hiatal/cirugía , Masculino , Paladar Blando/cirugía , Linaje , Faringe/cirugía , Procedimientos de Cirugía Plástica/métodos , Resultado del Tratamiento
18.
J Small Anim Pract ; 37(6): 280-5, 1996 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-8965482

RESUMEN

This article reviews Pneumocystis carinii and presents four cases in the miniature dachshund. The cases presented with hyperpnoea, tachypnoea and exercise intolerance. There were also clinical signs suggestive of immune incompetence in all the dogs. P carinii pneumonia was diagnosed in all four cases on transtracheal aspirate cytology. Immunological studies showed low globulin levels on serum electrophoresis, decreased lymphoblast transformation response (in the two cases that were tested) and a deficiency of immunoglobulins A, G and M. Light and electron microscopy as well as anti-canine immunoglobulin G immunoperoxidase staining studies were performed on one case which had died because of the disease. From these four cases, it appears that P carinii pneumonia in the miniature dachshund may be the result of an immunodeficiency. It does not, however, appear to be a classic primary severe combined immunodeficiency syndrome as the dogs appeared to respond to treatment, did not show growth failure and did not manifest overwhelming commensurate bacterial infections.


Asunto(s)
Enfermedades de los Perros/microbiología , Neumonía por Pneumocystis/veterinaria , Animales , Enfermedades de los Perros/inmunología , Perros , Femenino , Inmunoglobulinas/deficiencia , Neumonía por Pneumocystis/complicaciones , Neumonía por Pneumocystis/inmunología , Neumonía por Pneumocystis/microbiología
19.
J S Afr Vet Assoc ; 73(3): 133-4, 2002 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-12515302

RESUMEN

A young Donge de Bordeaux dog was presented with chronic intermittent antibiotic responsive gastrointestinal and respiratory disease. Further evaluation showed bacterial lymphadenitis, bacterial tracheitis, normal white cell and differential cell counts, hypogammaglobulinaemia, and the absence of B-lymphocytes but the presence of T-lymphocytes in the lymphoid tissue stained with lymphocyte markers. As the dog came from a narrow genetic base, with related dogs showing similar clinical signs, possible B-cell congenital immune deficiency was suspected.


Asunto(s)
Enfermedades de los Perros/inmunología , Perros/inmunología , Síndromes de Inmunodeficiencia/veterinaria , Animales , Enfermedades de los Perros/congénito , Perros/genética , Enfermedades Gastrointestinales/etiología , Enfermedades Gastrointestinales/inmunología , Enfermedades Gastrointestinales/veterinaria , Inmunidad Celular/fisiología , Síndromes de Inmunodeficiencia/congénito , Síndromes de Inmunodeficiencia/inmunología , Masculino , Infecciones del Sistema Respiratorio/etiología , Infecciones del Sistema Respiratorio/inmunología , Infecciones del Sistema Respiratorio/veterinaria
20.
J S Afr Vet Assoc ; 71(1): 43-6, 2000 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-10949517

RESUMEN

A questionnaire survey of 716 veterinary practices was undertaken to determine the incidence of Spirocerca lupi in dogs in South Africa. In total, 49% of the questionnaires were returned, indicating a possible incidence of 28%. Fewer than 4 cases per year were recorded by 82% of the respondents; 4-12 by 14%; 12-24 by 3%; and more than 48 by only 1%. No seasonal incidence was reported by 48% of the respondents. Large breeds were considered to be at greater risk by 43% of respondents. No specific age or sex was identified to be at higher risk. The most common complaints by owners and clinical findings were vomiting (46%), weight loss (27%), coughing (21%) or regurgitation (20%), although 14% of respondents reported no abnormal clinical findings. Diagnostic methods used were radiology (74%), endoscopy (27%), post mortem examination (34%) and faecal flotation (4%). Complications associated with S. lupi were reported by 76% of respondents, which included oesophageal neoplasia (41%), hypertrophic osteopathy (38%) and acute haemothorax (30%). Specific treatments were used by 58% of the respondents, whereas 42% of the respondents either used no treatment (72%) or recommended euthanasia (28%). Of the treatment group, 52% used ivermectin, 27% doramectin, 13% other deworming drugs (benzimidazoles, nitroscanate), and 8% used disophenol. Sixty-three percent of the respondents considered their treatment ineffective, whereas 31% considered it effective, and 6% were unsure. The overall mortality rate was high.


Asunto(s)
Enfermedades de los Perros/epidemiología , Infecciones por Spirurida/veterinaria , Thelazioidea , Animales , Antinematodos/uso terapéutico , Cruzamiento , Enfermedades de los Perros/diagnóstico , Enfermedades de los Perros/terapia , Perros , Incidencia , Estaciones del Año , Sudáfrica/epidemiología , Infecciones por Spirurida/diagnóstico , Infecciones por Spirurida/epidemiología , Infecciones por Spirurida/terapia , Encuestas y Cuestionarios
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