Time to retire 'New daily persistent headache': Mode of onset of chronic migraine and tension-type headache.

New daily persistent headache is described as an enigmatic condition with daily headache from onset. It has posed challenges diagnostically and therapeutically.Methods: We conducted a study of patients referred to headache services based in Central and North-East London, United Kingdom, meeting the International Classificaiton of Headache Disorders - 3 criteria for New daily persistent headache. Information on demographics, phenotype and treatment responses were collected. The syndrome of the daily headache was also classified according any other ICHD-3-defined syndrome.Results: Of 162 patients, females comprised 68.5% with median age of onset 35 years. The daily headache experienced was chronic migraine in 89.7% and tension-type headache in 8.8%. Thunderclap-onset New daily persistent headache occurred in 14.8%. More than one headache syndrome was experienced in 15.4%, including cough, hypnic, sexual and stabbing headache. All aura types were experienced, most commonly brainstem aura in 39%. Prior headache was reported 53.7%. A persisting sub-form was present in 51.2%, relapsing remitting in 12.3% and 14.0% reported improvement; 19.8% were lost to follow-up. Only 11.1% reported an antecedent trigger. The most common premorbid disorders were psychiatric in 35.7%. A fifth improved on preventative medication, most commonly amitriptyline, propranolol and topiramate.Conclusion: Our cohort of New daily persistent headache is consistent with a mode of onset of migraine and tension-type headache which occurs in predisposed individuals.

The 50 most cited articles in ankle surgery.

This paper aims to establish a ranking of the 50 most cited research articles pertaining to ankle surgery in the field of orthopaedics. In addition, the demographic features such as the date of publications, location of primary author and country of the publisher were all analysed. Studies similar to these have been completed in other subspecialties, however we were not able to find studies relevant to ankle surgery. The Web of Science Cor Collection Database was utilised to identify the target articles. The most cited article was cited 394 times and the least was cited 120 times, and the majority of articles were published in the United States of America. This research will benefit the scientific community in identifying popular research topics, identifying lacking fields and identifying key hubs in the field of ankle surgery.

Knee surgery: Trends and the 50 most cited articles.

Knee Surgery is one of the most commonly performed orthopedic procedures, and a rapidly evolving area of research. A bibliographic analysis was conducted to explore the characteristics of the top 50 most cited articles in knee surgery. The Web of Science Core Collection Database was used to search for Knee AND Surgery, further refined for orthopedic surgery, yielding 1,660 articles. After inclusion and exclusion criteria were applied, the top 50 cited articles were statistically and thematically analyzed. Year of publication ranged from 1982 to 2014. The highest volume of research came from USA, with the Journal of Bone and Joint Surgery having the highest number of papers in the top 50. The most common theme of research was Knee Arthroplasty Outcomes. Our study elucidates trends and popular areas of research in the field of knee surgery, and provides researchers with an overview of areas to focus, where there is scope for high-impact original research.