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Clin Otolaryngol ; 42(3): 673-680, 2017 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-27882653

RESUMEN

OBJECTIVES: To study the development of synkinesis in Bell's palsy. Frequency, severity, gender aspects and predictors were analysed. DESIGN: Data from the randomised controlled Scandinavian Bell's palsy trial including 829 patients. MAIN OUTCOME MEASURES: Frequency and severity of synkinesis at 12 months were the main outcome measures. Mean Sunnybrook synkinesis scores, voluntary movement scores and composite scores between 6 and 12 months were compared. RESULTS: In 743 patients with a 12-month follow-up, synkinesis frequency was 21.3%. There was no gender difference. Synkinesis was moderate to severe in 6.6% of patients. Those with synkinesis at 6 months had a synkinesis score of 4.1 (±2.8 sd), which increased to 4.7 (±3.2) (P = 0.047) at 12 months (n = 93). Sunnybrook composite score at 1 month was the best predictor for synkinesis development with receiver operating characteristics and area under the curve (AUC) 0.87. Risk for synkinesis increased with a lower Sunnybrook composite score. Furthermore, at 1 month, symmetry of voluntary movement had higher predictive value for synkinesis than resting symmetry with AUC 0.87 and 0.77, respectively. Gentle eye closure and open-mouth smile were the only independent significant predictive items (AUC 0.86). CONCLUSIONS: Moderate-to-severe synkinesis was present in 6.6% of patients. The mean synkinesis score increased between 6 and 12 months, and outcome should therefore be evaluated after at least 12 months. Sunnybrook composite score and symmetry of voluntary movement at 1 month were good predictors for synkinesis.


Asunto(s)
Aciclovir/análogos & derivados , Parálisis de Bell/complicaciones , Prednisolona/administración & dosificación , Sincinesia/etiología , Valina/análogos & derivados , Aciclovir/administración & dosificación , Adolescente , Adulto , Anciano , Antivirales/administración & dosificación , Parálisis de Bell/diagnóstico , Parálisis de Bell/tratamiento farmacológico , Relación Dosis-Respuesta a Droga , Método Doble Ciego , Quimioterapia Combinada , Femenino , Estudios de Seguimiento , Glucocorticoides/administración & dosificación , Humanos , Masculino , Persona de Mediana Edad , Sincinesia/diagnóstico , Sincinesia/tratamiento farmacológico , Factores de Tiempo , Resultado del Tratamiento , Valaciclovir , Valina/administración & dosificación , Adulto Joven
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