[Clinico-immunologic parallels in atherosclerotic discirculatory encephalopathy]. / Kliniko-immunologicheskie paralleli pri ateroskleroticheskoi distsirkuliatornoi éntsefalopatii.

For disclosing the character of the immunological reactivity disturbances in atherosclerotic discirculatory encephalopathy the humoral and tissue immunity was examined in 160 patients. Signs of an increase of the hypersensitivity (both immediate and delayed) to local antigens were revealed, these signs correlating with the stage of the encephalopathy development. The changes discovered may be of a diagnostic and prognostic value in chronic forms of vascular encephalopathies.

[Differentiation of the epithelium of the pronephros and the primary kidney in frogs]. / Differentsirovka épiteliev predpochki i pervichnoi pochki u liagushki

The kidneys of tadpoles of different developmental stages were examined in preparations processed histologically and histochemically. It was found that differentiation of the provisory excretory organ tubules in frogs was "shortened" or "accelerated" after P. P. Ivanov's terminology, and developed differently as compared with differentiation of tubules of the definitive organ of excretion -- the primary kidney. When differentiating the epithelium of the proximal portion of the primary kidney nephron passes the stage of the high prismatic false-stratified epithelium. The pronephros tubules do not pass this stage and the epithelium becomes a strict monolayer from the very beginning. No mitoses are observed in the pronephros tubule epithelium even at the earliest differentiation stages. Later on, the beginning of tubule functioning, and with the reduction, and later disappearance of yolk granules in the epithelium solitary mitoses make their appearance. The mitotic activity of the primary kidney tubule epithelium is very high (70%) at the early stage of differentiation. Then its mitotic activity decreases (30%), and after the beginning of the tubule functioning mitoses in its epithelium become solitary.

[Correlation of the differentiation of the epithelium of provisory and definitive kidneys in vertebrates]. / Sootnoshenie differentsirovki épiteliev provizornoi i definitivnoi pochek u pozvonochnykh

Opisthonephros-the primary kidney of the frog-has features similar in its development to both primary and secondary kidneys of the rabbit, and at the same time they greatly differ from the frog's pronephros in the course of its development. It is in the development of the frog's pronephros where the regularity of shortened and accelerated differentiation of tissue of provisory organs as compared with definitive ones formulated by P.P. Ivanov has distinct manifestation. It is in agreement with the fact that the pronephros of lower vertebrates is considerably more primitive in its anatomical and physiological features than the primary and secondary kidneys of higher vertebrates which are in general similar with each other though functioning in different developmental periods.

[Changes in the myocardium of fetuses and newborn infants as a result of hypoxia]. / Izmeneniia miokarda u plodov i novorozhdennykh detei v usloviiakh gipoksii.

Myocardium has been investigated in 68 human fetuses and newborns suffered from intrauterine acute and prolonged hypoxia, occurred as a result of various maternal, fetal and placental diseases. Under acute hypoxia only reactive changes of the contractile myocardium appear. They are demonstrated as degeneration of muscle fibers and appearance of scattered foci of necrosis in cardiomyocytes. Under a prolonged hypoxia, besides analogous reactive changes, compensatory hypertrophy of some part of cardiomyocytes is noted; this is manifestation of a compensatory-adaptive reaction of the myocardium.