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1.
Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist.
Proc Natl Acad Sci U S A
; 114(7): 1649-1654, 2017 02 14.
Artículo
Inglés
| MEDLINE | ID: mdl-28143939
2.
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase.
Nat Chem Biol
; 12(4): 218-25, 2016 Apr.
Artículo
Inglés
| MEDLINE | ID: mdl-26829472
3.
Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase.
Proc Natl Acad Sci U S A
; 110(24): 9728-33, 2013 Jun 11.
Artículo
Inglés
| MEDLINE | ID: mdl-23716694
4.
Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket.
J Biol Chem
; 289(7): 4432-43, 2014 Feb 14.
Artículo
Inglés
| MEDLINE | ID: mdl-24356970
5.
Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase.
J Biol Chem
; 289(30): 20583-93, 2014 Jul 25.
Artículo
Inglés
| MEDLINE | ID: mdl-24895126
6.
Development of Dihydroxyphenyl Sulfonylisoindoline Derivatives as Liver-Targeting Pyruvate Dehydrogenase Kinase Inhibitors.
J Med Chem
; 60(3): 1142-1150, 2017 02 09.
Artículo
Inglés
| MEDLINE | ID: mdl-28085286
7.
Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion.
mBio
; 8(2)2017 04 04.
Artículo
Inglés
| MEDLINE | ID: mdl-28377530
8.
Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties.
J Med Chem
; 57(9): 3746-54, 2014 May 08.
Artículo
Inglés
| MEDLINE | ID: mdl-24697290
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