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J Laryngol Otol ; 136(3): 256-260, 2022 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-34689844

RESUMEN

OBJECTIVES: Electrochemotherapy uses electric fields to facilitate the influx of chemotherapy into cancer cells, producing a targeted effect. For head and neck cancer, it is mainly used for palliation of non-skin-origin metastases. It is used infrequently in the UK. This paper presents our experience and a UK survey to identify its frequency of use. METHODS: Between 2016 and 2019, a prospective database was created and reviewed. Only patients with non-skin-origin metastatic head and neck cancer, with no other palliative options, were included. Survival length, complications and symptomatic benefit were assessed. The survey was conducted via e-mail. RESULTS: Five patients were included: three with squamous cell carcinoma, one with esthesioneuroblastoma and one with hepatocellular carcinoma. Survival ranged from 1 month to over 20 months. Minor complications were seen. Only 15 out of 69 UK head and neck multidisciplinary teams offer electrochemotherapy. CONCLUSION: Electrochemotherapy is a well-tolerated adjunct to standard palliation of metastatic head and neck cancer, and is offered by a limited number of UK multidisciplinary teams.


Asunto(s)
Carcinoma Hepatocelular/tratamiento farmacológico , Carcinoma de Células Escamosas/tratamiento farmacológico , Electroquimioterapia , Estesioneuroblastoma Olfatorio/tratamiento farmacológico , Neoplasias de Cabeza y Cuello/tratamiento farmacológico , Cuidados Paliativos , Adulto , Anciano , Carcinoma Hepatocelular/secundario , Carcinoma de Células Escamosas/secundario , Estesioneuroblastoma Olfatorio/secundario , Neoplasias de Cabeza y Cuello/secundario , Humanos , Masculino , Estudios Retrospectivos , Encuestas y Cuestionarios , Resultado del Tratamiento , Reino Unido
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