[Investigating the incidence of injection-site reactions associated with administration of oxaliplatin into a peripheral vein and management local adverse reactions].

In Aichi Cancer Center Hospital, we investigated the incidence of injection-site reactions associated with the administration of Oxaliplatin into a peripheral vein. We evaluated the frequency and severity of symptoms, and studied ways to manage its adverse reactions from September 2009 through March 2010. Oxaliplatin was injected into a peripheral vein in more than 90% of patients, suggesting that there would be a high risk of injection-site reactions. About 60% of patients had a numeric rating score of 5 or higher in this study, and more than 60% of injection-site reactions were improved by warming the injection site. Our results suggest that warming the injection site is one effective way to manage local adverse reactions when Oxaliplatin is administered into a peripheral vein.

Photoinitiated Marangoni flow morphing in a liquid crystalline polymer film directed by super-inkjet printing patterns.

Slight contaminations existing in a material lead to substantial defects in applied paint. Herein, we propose a strategy to convert this nuisance to a technologically useful process by using an azobenzene-containing side chain liquid crystalline (SCLCP) polymer. This method allows for a developer-free phototriggered surface fabrication. The mass migration is initiated by UV-light irradiation and directed by super-inkjet printed patterns using another polymer on the SCLCP film surface. UV irradiation results in a liquid crystal-to-isotropic phase transition, and this phase change immediately initiates a mass migration to form crater or trench structures due to the surface tension instability known as Marangoni flow. The transferred volume of the film reaches approximately 440-fold that of the polymer ink, and therefore, the printed ink pattern acts as a latent image towards the amplification of surface morphing. This printing-aided photoprocess for surface inscription is expected to provide a new platform of polymer microfabrication.