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Curr Opin Microbiol ; 39: 48-56, 2017 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-28964986

RESUMEN

The complex heterogeneous structure of biofilms confers to bacteria an important survival strategy. Biofilms are frequently involved in many chronic infections in consequence of their low susceptibility to antibiotics as well as resistance to host defences. The increasing need of novel and effective treatments to target these complex structures has led to a growing interest on bacteriophages (phages) as a strategy for biofilm control and prevention. Phages can be used alone, as a cocktail to broaden the spectra of activity, or in combination with other antimicrobials to improve their efficacy. Here, we summarize the studies involving the use of phages for the treatment or prevention of bacterial biofilms, highlighting the biofilm features that can be tackled with phages or combined therapy approaches.


Asunto(s)
Infecciones Bacterianas , Biopelículas , Terapia de Fagos , Infección de Heridas , Animales , Infecciones Bacterianas/prevención & control , Infecciones Bacterianas/terapia , Modelos Animales de Enfermedad , Humanos , Ratones , Porcinos , Infección de Heridas/prevención & control , Infección de Heridas/terapia
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