Study of dynamic characteristics of air cavity resonances from tyre-pavement interaction noise using single frequency filtering.

Air cavities in the tyre tread and the gap formed between tyre and pavement are excited during vehicle movement on a pavement. The former results in pipe resonance, and the latter results in horn resonance. These effects will be varying with speed of the vehicle and also because of conditions of tyre, pavement and, tyre-pavement interaction (TPI). The objective of this paper is to study the dynamic characteristics of air cavity resonances from the signals of the tyre-pavement interaction noise, which was collected by a pair of microphones, when a two wheeler is driven on a pavement at different speeds. The dynamic characteristics of the resonances are analysed using single frequency filtering (SFF) analysis of signals. The method gives spectral information at every sampling instant. The effects of impacts of the tyre treads, pavement characteristics, and TPI on the resulting cavity resonances are examined at four different vehicle speeds and for two different types of pavements. The analysis shows that the SFF spectra bring out the distinct characteristics of the pavements on the formation of air cavities and excitation of the resonances of these cavities. This analysis may help in determining the condition of the tyre and pavement.

Time-Frequency analysis of acoustic signals from tyre-pavement interaction.

The acoustic responses of a dynamical system reflect the characteristics of the external excitation and vibrating system. The objective in an identification problem is to characterise the system and excitation from the measured responses. This becomes challenging if the characteristics of the dynamical system are time-varying. The analysis of the acoustic signal generated as a result of the tyre-pavement interaction (TPI) is one such situation, where in order to study the time-varying nature there is a need to obtain the characteristics of the instantaneous response. This study explores the single frequency filtering analysis of signals to examine the time-varying characteristics of tyre-pavement interaction noise (TPIN). Field measurements of TPI acoustic signals were obtained for a two-wheeler driven at different speeds on asphalt and cement concrete pavements. The time-frequency characteristics of the tyre tread impact and of the air cavity resonances are analysed by investigating the effect of vehicular speed and pavement type on TPIN. The specific features of TPIN such as the harmonics due to periodic tread impact and the frequency response due to resonances of the air cavities are examined in detail. The analysis presented in this paper will be useful in developing methods for health monitoring of tyre and pavement systems.

Ultrasound-guided musculoskeletal interventions in American football: 18 years of experience.

OBJECTIVE: Myotendinous strains, contusions, and hematomas are common injuries in American football. Along with ligament sprains and inflammatory disorders, musculoskeletal injuries often result in lost participation time. This article summarizes 18 years of experience with 128 ultrasound-guided drainages and injections in 69 football players with 88 injuries. CONCLUSION: When performed by an operator with sufficient expertise in diagnostic and procedural skills, ultrasound-guided musculoskeletal interventions are minimally invasive, are safe, and can play an integral role in injury management.

Association of Periodontal Red Complex Bacteria With the Incidence of Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.

Porphyromonas gingivalis is the primary microbe in the "periodontal red complex" bacteria (PRCB) along with Tannerella forsythia and Treponema denticola, which are linked to periodontal disease (PD). These pathogens are also implicated in various systemic disorders, but their association with the incidence of gastrointestinal (GI) cancer is less explored. A systematic review followed by a meta-analysis was conducted as per standard guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2022) to find this association between GI cancers and PRCB after a literature search for full-text papers in the English language (between 2010 and 2023) in databases (Cochrane Library, PubMed, and Web of Science) with suitable keywords using the Boolean search strategy. Data extraction involved titles, abstracts, and full texts retrieved and scored by the modified Newcastle-Ottawa Scale. The data were analyzed by the Review Manager (RevMan 5.2, Cochrane Collaboration, Denmark). Standard Cochran Q test and I2 statistics (for heterogeneity) and a random effects model (pooled OR with 95% CI) were applied to report results. P. gingivalis among the PRCB was linked to GI cancers (OR: 2.16; 95% CI: 1.34-3.47). T. forsythia and T. denticola did not show meaningful associations as per existing evidence for GI cancers.

Residue dynamics of spirotetramat and imidacloprid in/on mango and soil.

Spirotetramat is a unique insecticide having both phloem and xylem mobility and imidacloprid, a neonicotinoid insecticide, is one of the most widely used in the world. The combination formulation is very effective against sucking pests of mango. Residue dynamics of spirotetramat and imidacloprid in/on mango and soil was studied following application of the combination formulation, spirotetramat 12% + imidacloprid 12% (240 SC) at 90 and 180 g a.i. ha(-1). Spirotetramat residues in/on mango fruits were 0.327 and 0.483 mg kg(-1) after giving 3 applications at 90 and 180 g a.i. ha(-1), respectively. The residues remained on mango fruits for 7 days and dissipated with the half-life of 3.3 and 5.2 days, respectively. Residues of spirotetramat-enol, the major metabolite of spirotetramat in plant, were not detected in mango fruits. Initial residues of imidacloprid on mango fruits from the two treatments were 0.329 and 0.536 mg kg(-1), respectively. Imidacloprid residues remained on mango fruits beyond 15 days and dissipated with the half-life of 5.2 and 8.2 days. The residues of spirotetramat, spirotetramat-enol and imidacloprid were found below quantifiable limit of 0.05 mg kg(-1) in mature mango fruits and field soil at harvest.

Comparative evaluation of oxygen saturation levels using pulse oxymeter during nonsurgical and surgical periodontal therapy in chronic periodontitis patients.

BACKGROUND AND AIM: Monitoring is the global method of observation and data recording in relation to body organ and system function that afford constant information to ensure continuous evalutation of the patient's physical condition. Basic monitoring provides essential information for assessing the vital signs, both circulatory and respiratory, and fundamentally comprises the control of blood pressure (BP) and heart rate (HR) and rhythm. Pulse oxymetry is used to record HR and oxygen saturation. The objective of the study was to assess and compare hemodynamic changes by monitoring oxygen saturation level changes during periodontal surgical and nonsurgical therapy. MATERIALS AND METHODS: A cross-sectional observational study was conducted in 30 chronic periodontitis patients. Patients were divided into two groups; Group A consisted of 15 patients undergoing surgical periodontal therapy, Group B consisted of 15 patients undergoing nonsurgical periodontal therapy. The hemodynamic changes were evaluated by monitoring HR and oxygen saturation level using pulse oxymeter (SaO2). HR and SaO2 were monitored continuously and registered pre-operatively, i.e. 10 minutes before the procedure, intra-operatively and postoperatively, i.e. 10 minutes after the procedure. One-way analysis of variance test (ANOVA) was performed for data analysis. RESULTS: Both the groups showed a slight fall in oxygen saturation levels intraoperatively, but within the normal range. More decrease in oxygen saturation levels was observed in nonsurgical periodontal therapy as compared to surgical periodontal therapy at intraoperative levels. The differences in the values were statistically significant. There was no statistical difference seen in the postoperative and preoperative values. CONCLUSION: Most of the hemodynamic changes induced during the periodontal therapy were within normal limits, taking into consideration the anxiety and stress produced by the surgical intervention. The hemodynamic change was more in nonsurgical as compared to surgical periodontal therapy.

Efficacy of low-dose caudal clonidine in reduction of sevoflurane-induced agitation in children undergoing urogenital and lower limb surgery: a prospective randomised double-blind study.

BACKGROUND: Sevoflurane is commonly used as an inhalational induction agent in paediatric patients. Emergence agitation is a common post-operative problem in young children who have received sevoflurane. Clonidine has proven to be effective in reducing the incidence of post-operative agitation at a higher dose (3 and 2 µg kg⁻¹). It has some dose-dependent disadvantages, prominently bradycardia, hypotension and respiratory impairment. OBJECTIVE: The authors conducted a study to evaluate the effectiveness of low-dose caudal clonidine (1 µg kg⁻¹) in reducing the incidence of sevoflurane-induced agitation in preschool children undergoing urogenital and lower limb surgery. METHODOLOGY: A double-blind study was conducted comparing 0.25% (0.75 ml kg⁻¹) bupivacaine and clonidine 1 µg kg⁻¹ (group 1), 0.25% bupivacaine (0.75 ml kg⁻¹) and clonidine 0.75 µg kg⁻¹ (group 2), with 0.25% bupivacaine (0.75 ml kg⁻¹) alone (group 3). Ninety children of 1-5 years of American Society of Anesthesiologists I and II were randomly assigned into three groups. Post-operatively, patients were monitored for 1 h to observe emergence agitation, which was assessed with the help of Pain and Discomfort Scale. RESULT: Post-anaesthetic agitation was observed in two patients (6.6%) in group 1, eight patients (26.6%) in group 2 as compared to 12 patients (40%) in group 3 after 15 min of post-operative observation. The mean scores in group 1 at 15 and 30 min were significantly lower than those in group 3 (P value <0.05). None of the groups had showed any haemodynamic and respiratory compromise, either clinically and statistically. CONCLUSION: Caudal clonidine at a lower dose (1 µg kg⁻¹) could be effective in reducing the incidence of sevoflurane-induced emergence agitation in children undergoing urogenital and lower limb surgery without any significant adverse effects.

Morbilliform Rash: An Uncommon Herald of SARS-CoV-2.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus first detected in Wuhan, China in 2019 after an outbreak of flu-like illness. The disease came to be known as the coronavirus disease of 2019 (COVID-19). It has spread quickly, spanning many countries, and has become a global pandemic. As this is a novel virus, its varied manifestations and symptomatology are coming to light daily. Although most threatening to the respiratory system, this virus has the propensity to affect multiple organ systems quickly leading to multi-organ dysfunction. Many dermatologic manifestations have been reported with no clear pattern. Most data have been anecdotal.  Here we present a 78-year-old male who tested positive for SARS-CoV-2 with no usual symptoms that would alert one of the possibilities of COVID-19. He did, however, have a diffuse morbilliform rash most notable on the trunk and back. He went on to develop fever thereafter but did not develop any respiratory complications. The rash was short-lived and was treated with topical steroids and oral antihistamines. It is important to know and report new findings of novel diseases not only for diagnosis and treatment but also to place appropriate isolation precautions and containment. Rash may be the initial and sometimes the only manifestation of COVID-19.

Persistence, dissipation and consumer risk assessment of a combination formulation of flubendiamide and deltamethrin on cucumber.

Multi-location supervised field trials were conducted in India at four locations of the All India Network Project (AINP) on Pesticide Residues to study the persistence, dissipation and risk assessment of flubendiamide and deltamethrin on cucumber (Cucumis sativus). Residues of flubendiamide and deltamethrin on cucumber resulting from three spray applications of a combination formulation (flubendiamide 90% + deltamethrin 60%, 150 SC) at recommended (22.5 + 15 g a.i./ha) and double the recommended (45 + 30 g a.i./ha) dose were analysed. On the basis of persistence and dissipation studies, the half- life (T1/2) of flubendiamide on cucumber varied from 1.40 to 2.98 (recommended dose) and 1.55 to 2.76 days (double the recommended dose), while that of deltamethrin ranged from 2.5 to 4.9 (recommended dose) and 2.7 to 3.9 days (double the recommended dose) at the four locations. On the basis of supervised field trial data and using OECD calculator, MRLs in the combination product of 3 mg kg-1 for flubendiamide and 1.5 mg kg-1 for deltamethrin has been proposed for consideration by the Food Safety and Standards Authority of India (FSSAI). Codex, EU and EPA have fixed MRL of 0.2 mg kg-1 for flubendiamide and deltamethrin.

Detection of Clostridium perfringens alpha toxin gene in lambs by loop mediated isothermal amplification.

AIM: The loop mediated isothermal amplification (LAMP) was standardized for rapid detection of Clostridium perfringens. MATERIALS AND METHODS: A total of 120 fecal samples were collected from enterotoxemia suspected lambs were used for screening of C. perfringens cpa gene by LAMP. The specificity of the LAMP amplified products was tested by digesting with restriction enzyme XmnI for alpha toxin gene. RESULTS: Out of 120 samples screened 112 (93.3%) samples were positive by both LAMP and polymerase chain reaction (PCR) for detection of cpa gene which indicated the equal sensitivity of both the tests. The enzyme produced single cut in 162 base pair amplified product of alpha toxin gene at 81 base pair resulting in a single band in gel electrophoresis. CONCLUSION: Both LAMP and PCR for detection of cpa gene indicated the equal sensitivity of both the tests. Standardization of LAMP reaction for amplification of epsilon and beta toxin genes will help to identify the C. perfringens toxin types from the clinical samples. The test could be a suitable alternative to the PCR in detection of toxin types without the help of sophisticated machinery like thermal cycler. Considering its simplicity in operation and high sensitivity, there is the potential use of this technique in clinical diagnosis and surveillance of infectious diseases.