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1.
Andrologia ; 49(7)2017 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-27596234

RESUMEN

Spermatozoa with a rare combination of two monomorphic sperm defects, dysplasia of the fibrous sheath (DFS) and alterations in head-mid-piece junction were analysed. The main focus was to explore the status of the centriole, a key organisation during fertilisation, using the centrin 1, a calcium-binding protein linked to this structure. The sperm quality was examined by light, scanning and transmission electron microscopy (SEM, TEM); immunocytochemistry was performed for tubulin, A-kinase anchor protein 4 (AKAP4) and centrin 1. Spermatozoa showed DFS defect associated with anomalies in head-tail attachment detected by SEM and TEM. Immunolocalisation of tubulin, AKAP4 and centrin 1 confirmed these alterations. Centrin 1 was visible in 67% of spermatozoa (in only 13% centrin localised in a normal position); in the majority of sperm centrin 1's location was altered, sometimes bent; often four spots, indicating the presence of two implantation fossae, were detected. At the centriolar level, immunoreactive fragments, frequently invading the entire short and thick tail, were observed. Centrin 1 is an essential component of the spermatozoa connecting piece and plays a role in centrosome dynamics during sperm morphogenesis and in zygotes and early embryos during spindle assembly. It is important to shed light on these rare conditions in order to better manage the patients during assisted reproductive technology.


Asunto(s)
Proteínas de Unión al Calcio/análisis , Proteínas de Ciclo Celular/análisis , Centriolos/ultraestructura , Cabeza del Espermatozoide/ultraestructura , Espermatozoides/anomalías , Espermatozoides/ultraestructura , Proteínas de Anclaje a la Quinasa A/análisis , Adulto , Humanos , Inmunohistoquímica , Infertilidad Masculina/patología , Italia , Masculino , Microscopía Electrónica de Rastreo , Microscopía Electrónica de Transmisión , Análisis de Semen , Cola del Espermatozoide/ultraestructura , Espermatozoides/química , Tubulina (Proteína)/análisis
2.
Andrologia ; 45(6): 392-6, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-23116262

RESUMEN

The cytotoxicity of Au/Ag nanoparticles (NPs) on human spermatozoa was investigated in vitro. Semen from donors were incubated (37 °C, 60'-120') with 30, 60, 125, 250 and 500 µM Au/Ag-NPs. Sperm motility was evaluated following WHO guidelines; sperm viability was assessed with eosin Y test. Au-NPs were characterised and localised with field emission gun-based scanning transmission electron microscope/energy dispersive spectroscopy and transmission electron microscopy. Both tested NPs exerted a significant dose-dependent effect on motility and viability of human spermatozoa (P < 0.001). Ag-NPs seem to show a slightly elevated toxicity although not significant (P > 0.05). Au-NPs were localised in spermatozoa, whereas Ag-NPs were undetectable. In conclusion, Au-NPs and Ag-NPs do not appear to be harmful for human spermatozoa up to high concentrations (250-500 µM) that are probably difficult to reach in vivo. It is mandatory to explore the genotoxic effect of NPs in germ cells.


Asunto(s)
Oro/efectos adversos , Nanopartículas del Metal/toxicidad , Plata/efectos adversos , Espermatozoides/efectos de los fármacos , Supervivencia Celular/efectos de los fármacos , Microanálisis por Sonda Electrónica , Humanos , Técnicas In Vitro , Masculino , Microscopía Electrónica de Transmisión , Motilidad Espermática/efectos de los fármacos
3.
J Cell Biol ; 88(1): 102-7, 1981 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-6451631

RESUMEN

Human spermatozoa with normal structure and with different axonemal deficiencies (absence of axoneme, of arms, or of central structures) were studied by electron microscopy, SDS-polyacrylamide gel electrophoresis, and ATPase activity measurements. Normal human sperm possess a complement of high molecular weight polypeptides with an electrophoretic migration similar to that of sea urchin and other mammalian sperm dyneins. Human high molecular weight bands are numbered one to four in order of increasing of electrophoretic mobility; all of them are absent in spermatozoa that lack axoneme. The absence of doublet arms, coincides with the absence of bands 2, 3, and 4; the absence of central structures coincides with a reduction in intensity of band 2. In the latter two abnormal conditions, band 1 has an increased intensity. The data are tentatively interpreted by attributing the polypeptides forming bands 3 and 4 to the arm structure, whereas band 2 is supposed to contain a mixture of polypeptides localized in the arms and in the central structures; these abnormal sperm contain modified polypeptides which gather in band 1. Histochemical ATPase stainings indicate that this enzyme is localized mainly in the doublet arms and, to a minor extent, in the central structures.


Asunto(s)
Adenosina Trifosfatasas/metabolismo , Dineínas/metabolismo , Infertilidad Masculina/patología , Espermatozoides/enzimología , Dineínas/análisis , Electroforesis en Gel de Poliacrilamida , Humanos , Masculino , Peso Molecular , Motilidad Espermática , Espermatozoides/ultraestructura
4.
J Androl ; 12(2): 104-11, 1991.
Artículo en Inglés | MEDLINE | ID: mdl-2050579

RESUMEN

A sperm defect causing infertility in two brothers is described. The malformation, named the "miniacrosome sperm defect," occurs in the total sperm population. It involves both the nuclei, which have a roundish apex, and the acrosomes, which are small, located in an apical position on the top of the nucleus, and sometimes ring-shaped. The midpiece and tail segments are normal, and the sperm are perfectly motile but fail to fertilize zona-free hamster ova in vitro. In spermatids, the absence of a microtubular manchette and reduction of the Golgi complex are evident.


Asunto(s)
Acrosoma/ultraestructura , Infertilidad Masculina/patología , Acrosoma/fisiología , Adulto , Animales , Núcleo Celular/ultraestructura , Cricetinae , Femenino , Humanos , Técnicas In Vitro , Infertilidad Masculina/genética , Infertilidad Masculina/fisiopatología , Masculino , Microscopía Electrónica , Microscopía Electrónica de Rastreo , Motilidad Espermática , Interacciones Espermatozoide-Óvulo
5.
Eur J Gastroenterol Hepatol ; 14(6): 663-9, 2002 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-12072601

RESUMEN

OBJECTIVE: To determine (1) the prevalence of Helicobacter pylori infection in male and female patients with reproductive disorders and controls; (2) the presence of anti-H. pylori antibodies in samples of follicular fluid, vaginal secretions and sperm; and (3) the existence of a structural homology between a major spermatozoa protein, tubulin, and H. pylori proteins. PATIENTS AND METHODS: Serum samples from 167 patients with infertility and 837 age- and gender-matched controls (blood donors) were examined by enzyme-linked immunosorbent assay (ELISA) and Western blotting to determine the seropositivity for H. pylori infection. The presence of anti-H. pylori antibodies in samples of follicular fluid, vaginal secretions and sperm was determined using the same techniques. The possible cross-reactivity with spermatozoa of anti-H. pylori hyperimmune sera and human antibodies was studied by immunofluorescence. The N-acid homology of human tubulin with the principal H. pylori proteins was assayed by the WU-blastp program available on the Internet. RESULTS: The prevalence of infection was significantly higher in patients than controls (49.1% v. 33.5%, P < 0.001). Follicular fluids from infected patients contained specific antibodies in all cases, sperm samples in about 50% of cases, and vaginal secretions in a minority of cases. Sera to H. pylori whole antigens and VacA reacted with the tails and the pericentriolar area of human spermatozoa (which are rich in tubulin); sera to urease and heat-shock protein (Hsp) did not. Follicular fluids with anti-H. pylori antibodies immune reacted with spermatozoa. A linear homology was found between beta-tubulin and three H. pylori proteins, flagellin, VacA and CagA. CONCLUSIONS: H. pylori infection may increase the risk of developing reproductive disorders or worsen the clinical expression of this syndrome.


Asunto(s)
Infecciones por Helicobacter/complicaciones , Helicobacter pylori/inmunología , Infertilidad/etiología , Adolescente , Adulto , Anticuerpos Antibacterianos/análisis , Western Blotting , Reacciones Cruzadas , Ensayo de Inmunoadsorción Enzimática , Femenino , Líquido Folicular/inmunología , Infecciones por Helicobacter/inmunología , Humanos , Infertilidad/inmunología , Masculino , Persona de Mediana Edad , Motilidad Espermática , Espermatozoides/inmunología , Tubulina (Proteína)/inmunología
6.
J Submicrosc Cytol Pathol ; 20(1): 209-24, 1988 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-3285991

RESUMEN

In this paper the Authors describe the localization of some significative proteins (acrosin, actin, tubulin, vimentin) detected by immunocytochemical methods in human infertile spermatozoa and correlate their distribution with the ultrastructural characteristics of the same spermatozoa, in order to clarify the structural bases of infertility.


Asunto(s)
Acrosoma/patología , Espermatozoides/patología , Acrosoma/anomalías , Acrosoma/ultraestructura , Microanálisis por Sonda Electrónica , Técnica del Anticuerpo Fluorescente , Humanos , Inmunohistoquímica , Infertilidad Masculina/patología , Masculino , Microscopía Electrónica , Proteínas/análisis , Espermatozoides/anomalías , Espermatozoides/análisis , Espermatozoides/ultraestructura
7.
J Submicrosc Cytol Pathol ; 21(2): 385-9, 1989 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-2752365

RESUMEN

The presence and localization of acrosin and hyaluronidase have been detected by immunocytochemistry in animals belonging to different phyla and characterized by the different structure of the acrosomal complex. Acrosin is widely distributed from Insecta to Echinodermata and Vertebrata; hyaluronidase has a similar diffusion, but seems to be absent from an Insect and from Echinodermata. The presence of extraacrosomal layer and perforatorium seems not to be related to that of the two enzymes, that are absent from Teleost species devoid of acrosome or having only a pseudoacrosome.


Asunto(s)
Acrosina/metabolismo , Acrosoma/enzimología , Artrópodos/enzimología , Equinodermos/enzimología , Hialuronoglucosaminidasa/metabolismo , Serina Endopeptidasas/metabolismo , Espermatozoides/enzimología , Vertebrados/metabolismo , Acrosoma/ultraestructura , Animales , Inmunohistoquímica , Masculino , Microscopía Electrónica , Microscopía Electrónica de Rastreo , Espermatozoides/ultraestructura
8.
J Submicrosc Cytol Pathol ; 23(2): 339-45, 1991 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-2070360

RESUMEN

In this paper the Authors describe the presence of HIV particles on and in mature spermatozoa either ejaculated by AIDS patients or incubated in vitro with HIV. Both kinds of spermatozoa have particles localized around the sperm organelles. In the first case, the nucleoid of the virus can be enveloped by a membrane-like coat or be devoid of it and form buddings in the plasma membrane. In the in vitro infected spermatozoa, only membrane enveloped nucleoids are present, and no process of budding can be found. The Authors conclude considering that the spermatozoa of the AIDS patients can be penetrated by the virus particles in different moments of their life, and show the HIV particles in different stages of their cycle: some of them have freshly penetrated the sperm, and are still contained in a membrane-like coat, others are replicated and are budding through the sperm plasma membrane. On the contrary, in vitro infected spermatozoa have only freshly penetrated virus particles, and lack buddings and membrane-free nucleoids. The presence of the HIV virus in spermatozoa is substantiated by labelling with monoclonal or polyclonal anti-HIV antibodies.


Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/microbiología , VIH/aislamiento & purificación , Espermatozoides/microbiología , Síndrome de Inmunodeficiencia Adquirida/patología , Membrana Celular/ultraestructura , VIH/inmunología , VIH/ultraestructura , Anticuerpos Anti-VIH/inmunología , Humanos , Masculino , Microscopía Electrónica , Microscopía Electrónica de Rastreo , Orgánulos/ultraestructura , Espermatozoides/patología , Espermatozoides/ultraestructura
9.
J Submicrosc Cytol Pathol ; 23(4): 659-65, 1991 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-1764692

RESUMEN

In this study we have selected a group of patients affected by a more or less severe condition of varicocele. After the evaluation of spermatogenesis and sperm function by electron microscopy we have demonstrated that the sperm malformations are mostly due to immaturity. Subsequently we have observed low FSH levels in the blood, concomitant with inhibin high contents, and we have studied Sertoli cells at submicroscopical level. In conclusion we suggest the following mode of action of varicocele in endocrinologically and spermatologically altered patients: varicocele----Sertoli cells----increased inhibin----hypophysis----decreased FSH----decreased testosterone----aberrant spermatogenesis----immature spermatozoa. The research will continue.


Asunto(s)
Hormona Folículo Estimulante/sangre , Inhibinas/sangre , Células de Sertoli/fisiología , Espermatozoides/fisiología , Varicocele/fisiopatología , Adulto , Humanos , Hormona Luteinizante/sangre , Masculino , Prolactina/sangre , Semen/citología , Recuento de Espermatozoides , Espermatozoides/ultraestructura , Tirotropina/sangre , Tiroxina/sangre , Varicocele/sangre , Varicocele/diagnóstico
10.
J Submicrosc Cytol Pathol ; 34(3): 241-53, 2002 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-12408357

RESUMEN

DU145 prostate carcinoma cells cultured on type III collagen possessed a highly migratory potential which was twice as much as HT-29 colon carcinoma cells. Prior to attachment to collagen, DU145 cells were highly reactive for fibronectin and after attachment clear zones between cells and collagen suggested protease activity. HT-29 cells attached to type III collagen forming dome-like polyps, however, tight and/or gap junctions were not observed. hFob osteoblasts were co-cultured with DU145 to establish a prostate cancer-collagen matrix barrier-bone cell metastasis model. Osteoblasts maintained their differentiated osteoblastic characteristics on one side of the collagen barrier, demonstrating high alkaline phosphatase, osteocalcin and insulin growth factor (IGF) activities. hFob cell growth was prominent adjacent to demineralized bone matrix particles (BMPs) embedded in type III collagen. The collagen matrix was deteriorated on the DU145 side of the collagen barrier. The DU145-collagen III-hFob model will allow an evaluation of the influence of the matrix on prostate cancer-bone cell interaction and regulation by growth factors.


Asunto(s)
Carcinoma/patología , Colágeno Tipo III/metabolismo , Células HT29/patología , Osteoblastos/patología , Neoplasias de la Próstata/patología , Fosfatasa Alcalina/metabolismo , Carcinoma/metabolismo , Carcinoma/ultraestructura , Técnicas de Cocultivo , ADN/análisis , Fibronectinas/metabolismo , Células HT29/metabolismo , Células HT29/ultraestructura , Humanos , Masculino , Modelos Biológicos , Osteoblastos/metabolismo , Osteoblastos/ultraestructura , Osteocalcina/metabolismo , Neoplasias de la Próstata/metabolismo , Neoplasias de la Próstata/ultraestructura , Somatomedinas/metabolismo
11.
Dev Biol ; 127(2): 443-51, 1988 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-3378674

RESUMEN

We studied the organization of the egg of a freshwater bivalve, Unio elongatulus. This egg is markedly polarized. At the vegetal pole there is a crater which constitutes the point of attachment of the growing oocyte to the ovarian wall. This has previously been interpreted as a micropyle. We show that the sperm does not enter the egg through the crater but in a differentiated region around it, mostly at its base. This region is characterized by a wrinkled surface and is the only site of the vitelline coat which specifically binds the lectin from Lotus tetragonolobus. The egg reacts explosively upon fertilization, ejecting vacuolar material from the crater. The role of this "egg reaction" in relation to the prevention of polyspermy is discussed.


Asunto(s)
Fertilización , Moluscos/embriología , Óvulo/fisiología , Interacciones Espermatozoide-Óvulo , Animales , Compartimento Celular , Femenino , Masculino , Microscopía Electrónica , Microscopía Electrónica de Rastreo , Moluscos/ultraestructura , Óvulo/ultraestructura
12.
Scan Electron Microsc ; 4: 151-6, 1981.
Artículo en Inglés | MEDLINE | ID: mdl-7347418

RESUMEN

This paper has been carried out in order to inquire whether some of the best known human malformations can be recognized by scanning electron microscopy. The SEM appearance of "straight tailed", "empty tailed", "short tailed", "round headed", "double", "old" human spermatozoa is described, and related to the inner structure. Straight tails and empty tails are quite evident at SEM. These defects are due to severe axonemal defects, related to dynein and tubulin deficiencies: "9+0", "arm less" and "axoneme less" spermatozoa are included in this category. Short tails and round heads are still more evident defects, due to complete absence of tail structures or acrosome and easily recognizable at SEM. Double spermatozoa are consistently in patients having abnormally high prolactin level and SEM is obviously sufficient for the diagnosis. Finally, spermatozoa in aged individuals show in SEM a peculiar shape due to absence of immature stages, reduced cytoplasm, disordered axoneme. It is concluded that SEM examination is a good tool for the identification of most of the best known human sperm abnormalities.


Asunto(s)
Espermatozoides/anomalías , Electroforesis , Humanos , Infertilidad Masculina/patología , Masculino , Microscopía Electrónica de Rastreo/métodos , Motilidad Espermática , Espermatozoides/ultraestructura
13.
Andrologia ; 9(4): 315-22, 1977.
Artículo en Inglés | MEDLINE | ID: mdl-596658

RESUMEN

Acrosome malformations of spermatids and spermatozoa in the testes of two infertile patients were investigated with the light and electron microscope. The first visible abnormalities appear at early spermatid stages. The detailed morphological analysis of the malformed spermatids shows that in most cases only the differentiation of the acrosome granule is interfered with. This may be the origin of the malformations of the mature spermatozoa. The fact that almost half the early spermatids lack the acrosome granule suggests that the original cause is genetic and that the genes are expressed in the haploid phase.


Asunto(s)
Acrosoma/ultraestructura , Infertilidad Masculina/patología , Espermatozoides/ultraestructura , Haploidia , Humanos , Masculino , Microscopía Electrónica , Espermátides/ultraestructura
14.
J Submicrosc Cytol ; 16(3): 585-600, 1984 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-6471151

RESUMEN

Semen and testicular biopsy samples from different aged human donors have been examined for any age related changes in sperm morphogenesis, structure and function. Various abnormalities and defects, some being unique to spermatozoon of elderly men, were observed at the light and electron microscope levels. In spite of this, the best fractions of ejaculated spermatozoa population maintains his function, as demonstrated by some complete egg penetrations observed with the 'zona free' hamster egg test system.


Asunto(s)
Espermatozoides/ultraestructura , Acrosoma/ultraestructura , Anciano , Animales , Biopsia , Cricetinae , Femenino , Grabado por Congelación , Humanos , Masculino , Microscopía Electrónica , Microscopía Electrónica de Rastreo , Morfogénesis , Semen/citología , Interacciones Espermatozoide-Óvulo , Testículo/citología , Testículo/crecimiento & desarrollo
15.
Andrologia ; 11(6): 437-43, 1979.
Artículo en Inglés | MEDLINE | ID: mdl-161145

RESUMEN

In this paper the peculiar case of an infertile man, possessing only normally shaped, but stiff and immotile spermatozoa is described. All the sperm are conventionally structured, with the constant characteristic of the absence of central tubules and projections forming the so-called central sheath. Electrophoretic analysis of the high molecular weight polypeptide chains attributed to dyneins shows the constant absence of one chain. The importance of the central structure, usually belonging to the "9 + 2" model spermatozoa, and the possible localization of a dynein chain in this region are discussed.


Asunto(s)
Infertilidad Masculina/diagnóstico , Motilidad Espermática , Espermatozoides/ultraestructura , Adulto , Dineínas/metabolismo , Electroforesis , Humanos , Masculino , Microscopía Electrónica , Microscopía Electrónica de Rastreo , Espermatozoides/anomalías
16.
Gamete Res ; 16(1): 10-21, 1987 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-3506897

RESUMEN

The action of gossypol on the acrosomal complex in rats has been investigated by microscopical and submicroscopical methods. The drug displays its morphological action only on spermatozoa during the transit through the epididymis, causing malformations and vesiculations. It appears to exert a primary action on the S-S groups formation, disturbing morphological molding occurring in this period and inhibiting capacitation.


Asunto(s)
Acrosoma/efectos de los fármacos , Gosipol/farmacología , Espermatozoides/efectos de los fármacos , Administración Oral , Animales , Histocitoquímica , Masculino , Microscopía Electrónica , Ratas
17.
Reproduction ; 125(6): 827-35, 2003 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-12773105

RESUMEN

Membrane vesicles were isolated from rabbit seminal plasma. Electron microscopy analyses showed the presence of numerous small, round vesicles with a diameter of about 70 nm. Determination of enzyme activities was carried out by high performance liquid chromatography and showed that the vesicles can degrade the diadenosine polyphosphates (ApnA), Ap3A and Ap4A and ATP and ADP, but not AMP. Studies of the degradation of diadenosine compounds by the vesicles present in seminal fluid showed an increasing production of AMP as the by-product and a time-dependent generation of dephosphorylated products consistent with the presence of ecto-ATP diphosphophosphatase (ecto-apyrase). In the presence of rabbit spermatozoa, AMP did not accumulate because 5'nucleotidase and adenosine deaminase, present at the surface of sperm cells, transformed AMP into adenosine and inosine. The effects of seminal fluid vesicles and diadenosine compounds on the acquisition of fertilizing capacity by rabbit spermatozoa were evaluated by Pisum sativum agglutinin fluorescein isothiocyanate conjugated staining. The results obtained with uncapacitated spermatozoa showed that the capacitating effector BSA could be substituted efficiently by the addition of diadenosine compounds and vesicles previously incubated for 2 h to the capacitative medium. Under these experimental conditions, the spontaneous acrosome reaction rate was not increased. Capacitated rabbit spermatozoa did not undergo acrosome reaction when l-alpha-lysophosphatidylcholine was substituted by diadenosine compounds previously incubated with vesicles. In conclusion, this study has shown that rabbit seminal fluid vesicles can degrade diadenosine compounds to AMP and that the addition of the vesicles and diadenosine compounds to uncapacitated rabbit spermatozoa favours the acquisition of the fertilizing capacity.


Asunto(s)
Reacción Acrosómica/efectos de los fármacos , Polifosfatos/farmacología , Vesículas Seminales/fisiología , Capacitación Espermática/efectos de los fármacos , 5'-Nucleotidasa/metabolismo , Adenosina/metabolismo , Adenosina Difosfato/farmacología , Adenosina Monofosfato/metabolismo , Adenosina Trifosfato/farmacología , Animales , Células Cultivadas , Cromatografía Líquida de Alta Presión/métodos , Fosfatos de Dinucleósidos/farmacología , Masculino , Microscopía Electrónica , Conejos , Vesículas Seminales/ultraestructura , Espermatozoides/metabolismo , Fosfolipasas de Tipo C/farmacología
18.
Andrologia ; 9(3): 255-64, 1977.
Artículo en Inglés | MEDLINE | ID: mdl-907211

RESUMEN

Sperm and testicular biopsies of an infertile human patient have been investigated using histochemical and electron microscopical technique. Spermiogram revealed a head defect, characterized with lacking acrosome and round and immature nucleoplasm, occuring in practically all cells and coiled tails in about a half of spermatozoa. EM study of spermatids has shown an abortive development of acrosome, whose primordium failed to attach the nucleus and expand, instead regressed. The nucleus failed in shaping and retarded in maturing, a disturbance apparently associated with the aplasia of hypoplasia of caudal manchette. The role of zinc in nuclear differentiation and the shape of head in the movement pattern are discussed.


Asunto(s)
Infertilidad Masculina/patología , Espermatozoides/ultraestructura , Acrosoma/ultraestructura , Núcleo Celular/ultraestructura , Humanos , Masculino , Cabeza del Espermatozoide/ultraestructura , Cola del Espermatozoide/ultraestructura , Espermátides/ultraestructura , Testículo/patología
19.
Andrologia ; 25(6): 325-9, 1993.
Artículo en Inglés | MEDLINE | ID: mdl-8279703

RESUMEN

In this note new consequences of the Kartagener's syndrome are described. In males the syndrome involved a diffused sperm immaturity; in one female severe skeletal defects were present probably resulting from bad organization of the renal apparatus.


Asunto(s)
Infertilidad Masculina/etiología , Síndrome de Kartagener/complicaciones , Adulto , Niño , Cilios/ultraestructura , Epitelio/ultraestructura , Femenino , Humanos , Síndrome de Kartagener/patología , Masculino , Mucosa Olfatoria/ultraestructura , Escoliosis/complicaciones , Situs Inversus/complicaciones , Espermatozoides/ultraestructura
20.
Andrologia ; 25(6): 331-5, 1993.
Artículo en Inglés | MEDLINE | ID: mdl-8279704

RESUMEN

In this note several cases of stunted tails involving the total sperm population in sterile humans are described. Half of the cases are classified as 'short tailed' spermatozoa, the other half as 'stump defect' previously described in bulls. Both defects are referred in details at electron microscopical level.


Asunto(s)
Infertilidad Masculina/patología , Cola del Espermatozoide/patología , Espermatozoides/anomalías , Acrosoma/fisiología , Adulto , Técnica del Anticuerpo Fluorescente , Humanos , Masculino , Microscopía Electrónica , Microscopía Electrónica de Rastreo , Mitocondrias/ultraestructura , Espermatozoides/ultraestructura , Infecciones Estafilocócicas/complicaciones , Staphylococcus epidermidis
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