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Am J Med ; 80(5): 770-6, 1986 May.
Artículo en Inglés | MEDLINE | ID: mdl-3635355

RESUMEN

Over a 15-month period, seven intravenous drug abusers had 10 admissions because of bacteremia due to methicillin-resistant Staphylococcus aureus. Seven episodes of probable bacterial endocarditis occurred in four patients; one patient had septic thrombophlebitis and two had soft tissue infections. All seven patients patronized a local "shooting gallery" where paraphernalia were provided and drugs were often administered by a "street doctor." All isolates were phage type 29/77/83A/84/85 and demonstrated resistance only to methicillin, oxacillin, and penicillin. This strain of methicillin-resistant S. aureus has a phage type and antibiogram that is distinct from nosocomial methicillin-resistant S. aureus and was probably acquired by intravenous drug abusers during visits to the "shooting gallery". The "shooting gallery" is an integral part of the drug culture and a likely source for the transmission of antibiotic-resistant organisms.


Asunto(s)
Dependencia de Heroína/complicaciones , Meticilina/antagonistas & inhibidores , Sepsis/microbiología , Infecciones Estafilocócicas/microbiología , Staphylococcus aureus/efectos de los fármacos , Adulto , Relación Dosis-Respuesta a Droga , Endocarditis Bacteriana/microbiología , Dependencia de Heroína/microbiología , Humanos , Masculino , Pruebas de Sensibilidad Microbiana , Persona de Mediana Edad , Osteomielitis/microbiología , Resistencia a las Penicilinas , Staphylococcus aureus/aislamiento & purificación
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