Detalles de la búsqueda
1.
Acylhydrazones as isoniazid derivatives with multi-target profiles for the treatment of Alzheimer's disease: Radical scavenging, myeloperoxidase/acetylcholinesterase inhibition and biometal chelation.
Bioorg Med Chem
; 28(10): 115470, 2020 05 15.
Artículo
Inglés
| MEDLINE | ID: mdl-32278712
2.
A novel mechanism of functional cooperativity regulation by thiol redox status in a dimeric inorganic pyrophosphatase.
Biochim Biophys Acta Gen Subj
; 1861(1 Pt A): 2922-2933, 2017 Jan.
Artículo
Inglés
| MEDLINE | ID: mdl-27664315
3.
Design and Synthesis of New Anthranyl Phenylhydrazides: Antileishmanial Activity and Structure-Activity Relationship.
Pharmaceuticals (Basel)
; 16(8)2023 Aug 09.
Artículo
Inglés
| MEDLINE | ID: mdl-37631035
4.
Synthesis and characterization of the atropisomeric relationships of a substituted N-phenyl-bipyrazole derivative with anti-inflammatory properties.
Chirality
; 24(6): 463-70, 2012 Jun.
Artículo
Inglés
| MEDLINE | ID: mdl-22544569
5.
Application of 4D-QSAR studies to a series of raloxifene analogs and design of potential selective estrogen receptor modulators.
Molecules
; 17(6): 7415-39, 2012 Jun 15.
Artículo
Inglés
| MEDLINE | ID: mdl-22706372
6.
(R)-(+)-Lasiodiplodin isolated from the endophytic fungus Sordaria tamaensis exhibits potent antimycobacterial and anti-inflammatory activities in vitro and in vivo: a dual approach for the treatment of severe pulmonary tuberculosis.
J Pharm Pharmacol
; 74(3): 446-457, 2022 Mar 03.
Artículo
Inglés
| MEDLINE | ID: mdl-34850064
7.
A Novel Protocol for the Synthesis of 1,2,4-Oxadiazoles Active against Trypanosomatids and Drug-Resistant Leukemia Cell Lines.
Trop Med Infect Dis
; 7(12)2022 Nov 28.
Artículo
Inglés
| MEDLINE | ID: mdl-36548658
8.
In vitro anti-HMPV activity of meroditerpenoids from marine alga Stypopodium zonale (Dictyotales).
Molecules
; 16(10): 8437-50, 2011 Oct 10.
Artículo
Inglés
| MEDLINE | ID: mdl-21986522
9.
Natural products from Brazilian biodiversity identified as potential inhibitors of PknA and PknB of M. tuberculosis using molecular modeling tools.
Comput Biol Med
; 136: 104694, 2021 09.
Artículo
Inglés
| MEDLINE | ID: mdl-34365277
10.
Inhibition of Aedes aegypti DNA topoisomerase II by etoposide: Impact on survival and morphology of larvae and pupae.
Comp Biochem Physiol C Toxicol Pharmacol
; 247: 109066, 2021 Sep.
Artículo
Inglés
| MEDLINE | ID: mdl-33930525
11.
Mechanism of resistance to acyclovir in thymidine kinase mutants from Herpes simplex virus type 1: a computational approach.
J Biomol Struct Dyn
; 38(7): 2116-2127, 2020 Apr.
Artículo
Inglés
| MEDLINE | ID: mdl-31190614
12.
Structural insights into IKKbeta inhibition by natural products staurosporine and quercetin.
Bioorg Med Chem Lett
; 19(24): 6907-10, 2009 Dec 15.
Artículo
Inglés
| MEDLINE | ID: mdl-19896375
13.
Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates.
Bioorg Med Chem
; 17(2): 641-52, 2009 Jan 15.
Artículo
Inglés
| MEDLINE | ID: mdl-19110434
14.
Discovery of novel analgesic and anti-inflammatory 3-arylamine-imidazo[1,2-a]pyridine symbiotic prototypes.
Bioorg Med Chem
; 17(1): 74-84, 2009 Jan 01.
Artículo
Inglés
| MEDLINE | ID: mdl-19059783
15.
Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally effective anti-inflammatory drug candidates.
Bioorg Med Chem
; 17(3): 1125-31, 2009 Feb 01.
Artículo
Inglés
| MEDLINE | ID: mdl-19135376
16.
Multi-target natural products as alternatives against oxidative stress in Chronic Obstructive Pulmonary Disease (COPD).
Eur J Med Chem
; 163: 911-931, 2019 Feb 01.
Artículo
Inglés
| MEDLINE | ID: mdl-30612088
17.
Virtual screening and drug repositioning as strategies for the discovery of new antifungal inhibitors of oxidosqualene cyclase.
J Steroid Biochem Mol Biol
; 185: 189-199, 2019 01.
Artículo
Inglés
| MEDLINE | ID: mdl-30193921
18.
The effects of Roundup® in embryo development and energy metabolism of the zebrafish (Danio rerio).
Comp Biochem Physiol C Toxicol Pharmacol
; 222: 74-81, 2019 Aug.
Artículo
Inglés
| MEDLINE | ID: mdl-30981909
19.
CNS-selective noncompetitive cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline.
Eur J Pharmacol
; 580(3): 339-49, 2008 Feb 12.
Artículo
Inglés
| MEDLINE | ID: mdl-18096154
20.
Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action.
Bioorg Med Chem Lett
; 18(3): 1162-6, 2008 Feb 01.
Artículo
Inglés
| MEDLINE | ID: mdl-18083513