[Several structural aspects of the interaction of yeast hexokinase with insulin]. / Nekotorye strukturnye aspekty vzaimodeistviia drozhzhevoi geksokinazy s insulinom

It has been noted that due to formation of the complex with insuline light and hear resistance of hexokinase from baker's yeast rises. Variation of luminescence parameters shows structural modification of enzyme upon complex formation. On the basis of comparison the photoinactivation data and hexokinase photolysis conclusion has been drawn that the tryptophanyl residues are not directly involved in the enzyme active site, although play an important role in supporting the specific structure.