RESUMEN
Data of 22 patients with primary double tumors are reviewed, collected from a total of 39.000 clinical protocols of which 1.168 were malignant. All were histologically verified. Criteria were those established by Warren & Gates i.e. a) each tumor must present clear signs of malignancy, b) each tumor must be different from the other, c) all possibility that one tumor may be a metastasis of the other must be excluded. Twelve of the cases were male and 10 female, representing 1.88% of the total with malignancies. In 6 cases both tumors appeared simultaneously, while the time interval was between 1 and 43 years in the remaining 16. Hematologic neoplasias are predominant with 12/44, followed by digestive and urogenital ones with 8/44 in each sub-group. Association between double tumors is assessed and causal factors which may influence or favor the appearance of two or more neoplasias are discussed.
Asunto(s)
Neoplasias Primarias Múltiples/patología , Adulto , Anciano , Femenino , Humanos , Leucemia/patología , Masculino , Persona de Mediana Edad , Neoplasias Primarias Múltiples/epidemiologíaRESUMEN
Epidemiological data from two series of patients in whom acute pancreatitis (AP) was diagnosed, with a chronological difference of four years between them, were compared. A total of 142 events of AP were analyzed from 128 clinical records. The mean age of incidence was significantly higher among the most recent series (61.04 +/- 17.83 years vs 51.66 +/- 14.06 years), and no differences were observed with regard to distribution by sex. The most frequent etiology in both series was biliary lithiasis, followed by ethylism, both of them clearly associated with female and male sex, respectively. In the AP of alcoholic etiology, the mean age at onset was smaller than in the other etiological groups and this observation was more evident in the second series. Finally, mortality was significantly reduced in the most recent series (12.3% for the first series vs 5.7% for the second series).