[Informational assets of glucose tolerance test in evaluation of endurance to psychoemotional stress]. / Informativnost' testa tolerantnosti k gliukoze v otsenke perenosimosti psikhoémotsional'nykh nagruzok.

Psychoemotional stresses were simulated in male volunteers in order to evaluate the predictive value of the glucose-tolerance test patterns. As was found, the predictive information is provided by the following parameters: Rafalsky and Boduen coefficients, glucose levels during 60-min testing, and the hypoinsulinemia coefficient. Operator's performance under the condition of time constraint is directly dependent on the insulin content. Based on results of the discriminative analysis key guidelines for classification of individuals by their resistance to the psychoemotional factor were proposed. In view of the informational assets the authors suggest that this approach should be more actively used in development of programs of functional testing of humans in extreme environments. Analysis of determined relationships gave rise to the supposition that desensitization of cell membrane receptors to insulin is the most probable cause for the detriment of the resistance to psychoemotional stresses.

[Biochemical evaluation of various respiration conditions during simulation of extended flight]. / Biokhimicheskaia otsenka razlichnykh rezhimov dykhaniia v usloviiakh modelirovaniia dlitel'nogo poleta.

During a simulated long-term mission with participation of male volunteers biochemical effects of various conditions of oxygen supply including breathing the cabin air at 2.4 km, pure oxygen, and intermittent hypoxia/hyperoxia, i.e. breathing the cabin air for 50 min and pure O2 for 10 min every hour in flight were studied. This assessment of respiration conditions by biochemical criteria allowed to recognize the combination of short hyperoxia and cabin air as the optimum to be taken into accounted in attacking the problem of oxygen supply of aviators in extended flights.

[Fat loading test: biochemical criteria and informative value of the physical endurance assessment]. / Biokhimicheskie kriterii zhirovoi nagruzochnoi proby i ee informativnost' v otsenke perenosimosti fizicheskikh nagruzok.

Biochemical criteria of the fat loading test (FLT) were established and the search for interrelations between FLT biochemical variables and physiological parameters of dynamic physical testing (bicycle ergometry) was conducted in the experiment with participation of male volunteers. Relative gain in glucose, triglycerides, total cholesterol concentrations in blood, atherogenicity factor and insulin decrease after 3-hr FLT and reduction in blood concentrations of total cholesterol, insulin, hydrocortisone and testosterone after 9-hr FLT were ranked as reliable criteria. Rise in blood glucose and decrease in blood insulin after 3-hr FLT, and decrease in serum testosterone after 9-hr FLT were found to have prognostic value. Correlation between the FLT biochemical variables and physiological parameters as well as the package of regression analysis equations allow prediction for physical endurance. Yet, analysis of the correlation suggested that desensitization to insulin of the cell membrane cells should be a pathogenic mechanism of physical endurance decrement.