Detalles de la búsqueda
1.
Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.
Ann Neurol
; 93(6): 1158-1172, 2023 06.
Artículo
Inglés
| MEDLINE | ID: mdl-36843330
2.
Predicting clinical progression trajectories of early Alzheimer's disease patients.
Alzheimers Dement
; 20(3): 1725-1738, 2024 Mar.
Artículo
Inglés
| MEDLINE | ID: mdl-38087949
3.
Plasma Aß42/Aß40 and phospho-tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.
Alzheimers Dement
; 20(2): 1214-1224, 2024 Feb.
Artículo
Inglés
| MEDLINE | ID: mdl-37932961
4.
Clinical validation of the PrecivityAD2 blood test: A mass spectrometry-based test with algorithm combining %p-tau217 and Aß42/40 ratio to identify presence of brain amyloid.
Alzheimers Dement
; 20(5): 3179-3192, 2024 May.
Artículo
Inglés
| MEDLINE | ID: mdl-38491912
5.
E2730, an uncompetitive γ-aminobutyric acid transporter-1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy.
Epilepsia
; 64(10): 2806-2817, 2023 10.
Artículo
Inglés
| MEDLINE | ID: mdl-37539645
6.
Correlative serum biomarker analyses in the phase 2 trial of lenvatinib-plus-everolimus in patients with metastatic renal cell carcinoma.
Br J Cancer
; 124(1): 237-246, 2021 01.
Artículo
Inglés
| MEDLINE | ID: mdl-33024271
7.
First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor.
Br J Cancer
; 123(4): 525-533, 2020 08.
Artículo
Inglés
| MEDLINE | ID: mdl-32523090
8.
Lenvatinib plus pembrolizumab in patients with advanced endometrial cancer: an interim analysis of a multicentre, open-label, single-arm, phase 2 trial.
Lancet Oncol
; 20(5): 711-718, 2019 05.
Artículo
Inglés
| MEDLINE | ID: mdl-30922731
9.
In vitro evaluation of PET radiotracers for imaging synaptic density, the acetylcholine transporter, AMPA-tarp-γ8 and muscarinic M4 receptors in Alzheimer's disease.
Am J Nucl Med Mol Imaging
; 14(1): 1-12, 2024.
Artículo
Inglés
| MEDLINE | ID: mdl-38500748
10.
Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.
Proc Natl Acad Sci U S A
; 107(51): 22255-9, 2010 Dec 21.
Artículo
Inglés
| MEDLINE | ID: mdl-21139054
11.
CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease.
Nat Med
; 29(8): 1954-1963, 2023 08.
Artículo
Inglés
| MEDLINE | ID: mdl-37443334
12.
CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.
J Biol Chem
; 286(37): 32188-97, 2011 Sep 16.
Artículo
Inglés
| MEDLINE | ID: mdl-21730065
13.
Systematic Analysis of Genetic and Pathway Determinants of Eribulin Sensitivity across 100 Human Cancer Cell Lines from the Cancer Cell Line Encyclopedia (CCLE).
Cancers (Basel)
; 14(18)2022 Sep 19.
Artículo
Inglés
| MEDLINE | ID: mdl-36139690
14.
Mapping the ligand-binding site on a G protein-coupled receptor (GPCR) using genetically encoded photocrosslinkers.
Biochemistry
; 50(17): 3411-3, 2011 May 03.
Artículo
Inglés
| MEDLINE | ID: mdl-21417335
15.
Direct interaction between an allosteric agonist pepducin and the chemokine receptor CXCR4.
J Am Chem Soc
; 133(40): 15878-81, 2011 Oct 12.
Artículo
Inglés
| MEDLINE | ID: mdl-21905700
16.
High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab.
Mol Cancer Res
; 19(9): 1510-1521, 2021 09.
Artículo
Inglés
| MEDLINE | ID: mdl-34039647
17.
First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers.
J Immunother Cancer
; 8(1)2020 06.
Artículo
Inglés
| MEDLINE | ID: mdl-32554609
18.
Lenvatinib Plus Pembrolizumab in Patients With Advanced Endometrial Cancer.
J Clin Oncol
; 38(26): 2981-2992, 2020 09 10.
Artículo
Inglés
| MEDLINE | ID: mdl-32167863
19.
A phase 2 study of lenvatinib in patients with RET fusion-positive lung adenocarcinoma.
Lung Cancer
; 138: 124-130, 2019 12.
Artículo
Inglés
| MEDLINE | ID: mdl-31710864
20.
Phase I Dose-Escalation Study of the Multikinase Inhibitor Lenvatinib in Patients with Advanced Solid Tumors and in an Expanded Cohort of Patients with Melanoma.
Clin Cancer Res
; 21(21): 4801-10, 2015 Nov 01.
Artículo
Inglés
| MEDLINE | ID: mdl-26169970