RESUMEN
Visceral Leishmaniasis (VL) is endemic in the Ganges and Brahmaputra plains of India. Leishmaniasis/HIV coinfection is on the rise in India and may pose a real diagnostic and therapeutic challenge. HIV-related immunosuppression increases the risk of reactivating leishmaniasis by 100 to 1000 times and it also increases the risk of drug resistant leishmaniasis. Immune reconstitution VL is not very well reported in literature. Hemophagocytosis is known to occur with various infectious agents like viruses, bacteria, and parasites, but is rare to occur with leishmaniasis. Here the authors describe a case of VL presenting as immune reconstitution disease and hemophagocytosis in an HIV infected patient coming from a nonendemic area.
Asunto(s)
Infecciones por VIH/complicaciones , Síndrome Inflamatorio de Reconstitución Inmune/etiología , Leishmaniasis Visceral/diagnóstico , Linfohistiocitosis Hemofagocítica/etiología , Adulto , Anemia/etiología , Médula Ósea/parasitología , Médula Ósea/patología , Recuento de Linfocito CD4 , Ferritinas/sangre , Fiebre/etiología , Humanos , Hipertrigliceridemia/etiología , Masculino , Esplenomegalia/etiología , Pérdida de PesoRESUMEN
Pseudothrombocytopenia (PTP) is defined by falsely low platelet counts on automated analyzers caused by in vitro phenomena including large platelet aggregates in blood samples. Diagnosis and resolution of PTP is crucial as it can lead to unwarranted interventions. We discuss a case of PTP in a pre-surgical setting, which was resolved using 37°C incubation and Kanamycin.