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BMC Musculoskelet Disord ; 19(1): 360, 2018 Oct 10.
Artículo en Inglés | MEDLINE | ID: mdl-30301459

RESUMEN

BACKGROUND: Local antibiotic therapy has gained increasing attraction in the prevention and treatment of fracture infection. However, no reports have used local antibiotic therapy in the management of early infection after fracture fixation with retention of implants. METHODS: The present surgical technique report the use of antibiotic impregnated bone cement in the management of early infection after fracture fixation. Initially, the fractures were fixed with plates. The average time from initial procedure to debridement was15 days (range 9 to 25 days). The infections were treated with irrigation, debridement, and retention of the implant. The lateral surface of the plates was coated with antibiotic cement and the bone defect was filled with antibiotic cement spacer after thorough debridement. RESULTS: Ten patients underwent this technique. The mean follow-up was 2.0 years (range 6 months to 4 years). The bone union rate was 100%, and the average time to bone healing was5.5 months.There was recurrence of infection in one patient before bone healing, but the implants were left in place until bone healed, and the infection was eradicated after implant removal. CONCLUSION: Coating the plate with antibiotic cement is a simple technique which may play a role in the management of early infection after fracture fixation.


Asunto(s)
Antibacterianos/uso terapéutico , Cementos para Huesos/uso terapéutico , Placas Óseas/efectos adversos , Materiales Biocompatibles Revestidos , Fijación de Fractura/instrumentación , Fracturas Óseas/cirugía , Infecciones Relacionadas con Prótesis/terapia , Adolescente , Adulto , Antibacterianos/efectos adversos , Cementos para Huesos/efectos adversos , Niño , Desbridamiento , Femenino , Fijación de Fractura/efectos adversos , Curación de Fractura , Fracturas Óseas/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Infecciones Relacionadas con Prótesis/diagnóstico , Infecciones Relacionadas con Prótesis/microbiología , Recurrencia , Factores de Riesgo , Irrigación Terapéutica , Factores de Tiempo , Resultado del Tratamiento , Adulto Joven
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