Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
1.
Emerg Infect Dis ; 20(3): 456-9, 2014 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-24572297

RESUMEN

An urban epidemic of dengue in Senegal during 2009 affected 196 persons and included 5 cases of dengue hemorrhagic fever and 1 fatal case of dengue shock syndrome. Dengue virus serotype 3 was identified from all patients, and Aedes aegypti mosquitoes were identified as the primary vector of the virus.


Asunto(s)
Virus del Dengue/clasificación , Dengue/epidemiología , Población Urbana , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Niño , Preescolar , Dengue/historia , Virus del Dengue/genética , Femenino , Historia del Siglo XXI , Humanos , Lactante , Masculino , Persona de Mediana Edad , Filogenia , Senegal/epidemiología , Serotipificación , Dengue Grave/epidemiología , Dengue Grave/historia , Adulto Joven
2.
Jpn J Infect Dis ; 61(4): 307-9, 2008 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-18653976

RESUMEN

From May 2004 to October 2006, a prospective study was carried out in Dakar, Senegal, to update information about the antimicrobial susceptibility of Shigella spp. isolated from stool specimens. Among the 165 non-duplicate strains collected, 81 (49%) were identified as Shigella flexneri, 75 (45%) as Shigella sonnei, 5 (3%) as Shigella boydii, and 4 (2%) as Shigella dysenteriae. Disk diffusion testing revealed that the majority of isolates were resistant to sulphonamides, trimethoprim-sulfamethoxazole, streptomycin, and tetracycline (respective overall resistance rates: 90, 90, 96, and 94%). More than half of the S. flexneri isolates were resistant to amoxicillin, amoxicillin-clavulanic acid, and chloramphenicol (respective resistance rates: 59, 58, and 52%), and almost all of the S. sonnei isolates were susceptible to these antimicrobials (respective resistance rates: 4, 1, and 4%). Only one isolate (belonging to the species S. sonnei) was resistant to nalidixic acid and displayed reduced susceptibility to ciprofloxacin.


Asunto(s)
Antibacterianos/farmacología , Farmacorresistencia Bacteriana , Disentería Bacilar , Shigella/clasificación , Shigella/efectos de los fármacos , Adolescente , Adulto , Anciano , Niño , Preescolar , Pruebas Antimicrobianas de Difusión por Disco , Disentería Bacilar/epidemiología , Disentería Bacilar/microbiología , Heces/microbiología , Humanos , Lactante , Persona de Mediana Edad , Senegal/epidemiología , Shigella/aislamiento & purificación , Shigella boydii/efectos de los fármacos , Shigella boydii/aislamiento & purificación , Shigella dysenteriae/efectos de los fármacos , Shigella dysenteriae/aislamiento & purificación , Shigella flexneri/efectos de los fármacos , Shigella flexneri/aislamiento & purificación , Shigella sonnei/efectos de los fármacos , Shigella sonnei/aislamiento & purificación , Especificidad de la Especie
3.
Diagn Microbiol Infect Dis ; 47(4): 595-600, 2003 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-14711481

RESUMEN

To assess antibiotic susceptibility among Enterobacteriaceae isolated in urine from outpatients in Dakar, Senegal, a prospective multicenter study involving 3 laboratories had been conducted between June and October 2001. During this period, 300 strains were isolated and susceptibility testing was performed against antibiotics commonly used in treatment of community-acquired urinary tract infections (UTI). E. coli and K. pneumoniae represented 89% of isolates. The overall resistance rates of ampicillin, amoxicillin-clavulanic acid, nalidixic acid, fluoroquinolones and cotrimoxazole were respectively 77.3%, 34.7%, 14.7%, 13.3%, and 55%. In the light of these results, a re-evaluation of first line therapies and prudent use of fluoroquinolones is advised. At the same time a continued surveillance of antimicrobial resistance should be developed in Senegal in order to control the emergence of multidrug resistant strains and to establish a national therapeutic guideline for treatment of UTI.


Asunto(s)
Antibacterianos/farmacología , Farmacorresistencia Bacteriana Múltiple , Infecciones por Enterobacteriaceae/tratamiento farmacológico , Enterobacteriaceae/efectos de los fármacos , Infecciones Urinarias/tratamiento farmacológico , Adolescente , Adulto , Intervalos de Confianza , Enterobacteriaceae/aislamiento & purificación , Infecciones por Enterobacteriaceae/diagnóstico , Infecciones por Enterobacteriaceae/epidemiología , Femenino , Humanos , Masculino , Pruebas de Sensibilidad Microbiana , Prevalencia , Probabilidad , Estudios Prospectivos , Medición de Riesgo , Senegal/epidemiología , Población Urbana , Infecciones Urinarias/epidemiología , Infecciones Urinarias/microbiología
5.
J Infect Dev Ctries ; 1(3): 263-8, 2007 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-19734603

RESUMEN

BACKGROUND: Data regarding the evolution of antimicrobial resistance are needed to suggest appropriate empirical treatment of urinary tract infections (UTI) in developing countries. To assess the antimicrobial susceptibility of Escherichia coli, the predominant pathogen in community-acquired UTI, a prospective multicenter study was carried out in Dakar, Senegal. METHODOLOGY: From February 2004 to October 2006, 1010 non-duplicate E. coli strains were collected from four centres. Antimicrobial susceptibility testing was performed using disk diffusion method according to the recommendations of the CA-SFM (2004). RESULTS: Most of the isolates were resistant to amoxicillin (73.1%), amoxicillin-clavulanic acid (67.5%), cephalothin (55.8%), and trimethoprim/sulfamethoxazole (68.1%). Extended spectrum beta-lactamase was detected in 38 strains. The overall resistance rates to nalidixic acid, norfloxacin and ciprofloxacin were 23.9%, 16.4% and 15.5%, respectively. Most of the strains were susceptible to gentamicin, nitrofurantoin and fosfomycin (respective susceptibility rates, 93.8%, 89.9%, and 99.3%). During this period, a significant decrease in sensitivity was observed for cephalothin, fluoroquinolones and trimethoprim/sulfamethoxazole (p<0.001). CONCLUSIONS: These data suggest that trimethoprim/sulfamethoxazole may no longer be used as empirical treatment for community-acquired UTI in Dakar. In order to preserve the activity of fluoroquinolones for future years, alternatives such as fosfomycin or nitrofurantoin should be considered.


Asunto(s)
Farmacorresistencia Bacteriana Múltiple , Infecciones por Escherichia coli/microbiología , Escherichia coli/efectos de los fármacos , Infecciones Urinarias/microbiología , Adolescente , Adulto , Infecciones Comunitarias Adquiridas/tratamiento farmacológico , Infecciones Comunitarias Adquiridas/epidemiología , Infecciones Comunitarias Adquiridas/microbiología , Escherichia coli/aislamiento & purificación , Infecciones por Escherichia coli/tratamiento farmacológico , Infecciones por Escherichia coli/epidemiología , Femenino , Humanos , Incidencia , Masculino , Pruebas de Sensibilidad Microbiana , Persona de Mediana Edad , Pacientes Ambulatorios , Embarazo , Estudios Prospectivos , Senegal/epidemiología , Infecciones Urinarias/tratamiento farmacológico , Infecciones Urinarias/epidemiología , Adulto Joven
SELECCIÓN DE REFERENCIAS
Detalles de la búsqueda